iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Lch-049517

Ensembl Protein ID

ENSLACP00000017430.1

UniProt Accession

H3B6A9; H3B6A9_LATCH

Genbank Protein ID

ENSLACP00000017430

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AFYH01024694

Gene Name

ARHGEF6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLACG00000015353.1	ENSLACT00000017558.1	ENSLACP00000017430.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	4.90e-17	61.9	162	216

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           +v++ ++++++n+deL++ kGd+++v     +++gW++g  +l+gk+G fP+n+v++++
   Q: 162  VVKARFNFKPTNEDELSFSKGDIIYVS--RVEEGGWWEG--TLNGKKGWFPSNYVREVK 216
           6899**********************7..9999******..8**************997 PP

Organism

Latimeria chalumnae

Protein Sequence
(Fasta)

MNPEEQTVTW LISLGVLNSP KKTISDPEDF LKSSLKDGVV LCKLLDRVSP GSLQNKYCPE 60
PKTEAACLSN IKEFLRGCVS LKLETFEAND LYTGENFSRV LNTLAALNRS TQESAAERTC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAATCCAG AAGAGCAAAC TGTAACATGG TTAATATCAT TGGGGGTTTT AAATTCGCCT 60
AAAAAGACTA TTTCAGATCC CGAAGATTTC TTGAAGTCCT CTCTGAAGGA CGGAGTGGTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0344--Guanine-nucleotide releasing factor
KW-1185--Reference proteome

Interpro

IPR001715--CH-domain
IPR000219--DH-domain
IPR001331--GDS_CDC24_CS
IPR032409--GEF_CC
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR001452--SH3_domain

PROSITE

PS50021--CH
PS00741--DH_1
PS50010--DH_2
PS50003--PH_DOMAIN
PS50002--SH3

Pfam

PF16523--betaPIX_CC
PF00307--CH
PF00169--PH
PF00621--RhoGEF
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00033--CH
SM00233--PH
SM00325--RhoGEF
SM00326--SH3

Gene Ontology

GO:0005622--C:intracellular
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0035556--P:intracellular signal transduction
GO:0035023--P:regulation of Rho protein signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001631	Ailuropoda melanoleuca	61.64	0.00e+00	984.00
IUUC-Apl-003960	Anas platyrhynchos	73.53	0.00e+00	1129.00
IUUC-Aca-004988	Anolis carolinensis	70.27	0.00e+00	1052.00
IUUC-Aly-005591	Arabidopsis lyrata	39.34	1.00e-08	53.50
IUUC-Ago-008003	Ashbya gossypii	26.02	6.00e-14	72.80
IUUC-Ame-011546	Astyanax mexicanus	67.95	0.00e+00	1011.00
IUUC-Bta-013527	Bos taurus	69.07	0.00e+00	1075.00
IUUC-Cja-018935	Callithrix jacchus	68.43	0.00e+00	1040.00
IUUC-Cfa-021269	Canis familiaris	68.39	0.00e+00	1048.00
IUUC-Cpo-021620	Cavia porcellus	67.22	0.00e+00	1010.00
IUUC-Csa-023415	Chlorocebus sabaeus	68.56	0.00e+00	1047.00
IUUC-Cho-024736	Choloepus hoffmanni	47.75	7.00e-105	374.00
IUUC-Cin-025535	Ciona intestinalis	43.61	5.00e-85	308.00
IUUC-Cgl-026676	Colletotrichum gloeosporioides	41.67	2.00e-11	65.10
IUUC-Cne-026866	Cryptococcus neoformans	54.00	3.00e-13	71.20
IUUC-Dre-028580	Danio rerio	68.74	0.00e+00	1060.00
IUUC-Dno-029201	Dasypus novemcinctus	65.30	0.00e+00	1020.00
IUUC-Dor-030868	Dipodomys ordii	57.60	0.00e+00	801.00
IUUC-Dme-032219	Drosophila melanogaster	44.24	2.00e-98	353.00
IUUC-Ete-032236	Echinops telfairi	52.52	8.00e-148	517.00
IUUC-Eca-033500	Equus caballus	68.81	0.00e+00	1047.00
IUUC-Eeu-035269	Erinaceus europaeus	61.32	2.00e-123	436.00
IUUC-Fca-035683	Felis catus	67.74	0.00e+00	1031.00
IUUC-Fal-037611	Ficedula albicollis	73.71	0.00e+00	1124.00
IUUC-Gmo-038980	Gadus morhua	65.67	0.00e+00	988.00
IUUC-Gga-040940	Gallus gallus	74.09	0.00e+00	1124.00
IUUC-Gac-042203	Gasterosteus aculeatus	64.27	0.00e+00	1011.00
IUUC-Ggo-044755	Gorilla gorilla	68.43	0.00e+00	1042.00
IUUC-Hsa-046210	Homo sapiens	68.43	0.00e+00	1042.00
IUUC-Kpa-049278	Komagataella pastoris	28.45	8.00e-19	89.40
IUUC-Loc-052393	Lepisosteus oculatus	69.82	0.00e+00	1093.00
IUUC-Laf-054196	Loxodonta africana	68.13	0.00e+00	1013.00
IUUC-Mcc-055716	Macaca mulatta	68.43	0.00e+00	1045.00
IUUC-Meu-056285	Macropus eugenii	61.99	3.00e-168	585.00
IUUC-Mtr-058576	Medicago truncatula	37.93	1.00e-12	67.40
IUUC-Mga-060029	Meleagris gallopavo	74.04	0.00e+00	1140.00
IUUC-Mmr-060803	Microcebus murinus	68.30	0.00e+00	1036.00
IUUC-Mdo-062654	Monodelphis domestica	69.96	0.00e+00	1076.00
IUUC-Mmu-063479	Mus musculus	68.00	0.00e+00	1021.00
IUUC-Mpu-066065	Mustela putorius furo	68.30	0.00e+00	1026.00
IUUC-Mlu-068222	Myotis lucifugus	67.05	0.00e+00	1011.00
IUUC-Ncr-068791	Neurospora crassa	30.16	5.00e-12	67.00
IUUC-Nle-069379	Nomascus leucogenys	68.43	0.00e+00	1043.00
IUUC-Opr-070687	Ochotona princeps	53.38	4.00e-174	604.00
IUUC-Ont-072240	Oreochromis niloticus	61.21	0.00e+00	984.00
IUUC-Oan-073067	Ornithorhynchus anatinus	74.29	0.00e+00	1159.00
IUUC-Ocu-074852	Oryctolagus cuniculus	67.65	0.00e+00	1029.00
IUUC-Ola-086766	Oryzias latipes	53.58	0.00e+00	783.00
IUUC-Oga-089048	Otolemur garnettii	65.02	0.00e+00	913.00
IUUC-Oar-089339	Ovis aries	68.94	0.00e+00	1070.00
IUUC-Ptr-091162	Pan troglodytes	60.03	0.00e+00	747.00
IUUC-Pan-092666	Papio anubis	67.10	0.00e+00	1009.00
IUUC-Psi-093116	Pelodiscus sinensis	74.23	0.00e+00	1156.00
IUUC-Pma-094701	Petromyzon marinus	57.35	9.00e-121	426.00
IUUC-Pfo-097394	Poecilia formosa	67.48	0.00e+00	1009.00
IUUC-Pab-098567	Pongo abelii	68.43	0.00e+00	1042.00
IUUC-Pca-100997	Procavia capensis	60.13	0.00e+00	844.00
IUUC-Pva-102500	Pteropus vampyrus	67.01	0.00e+00	1004.00
IUUC-Rno-104974	Rattus norvegicus	68.56	0.00e+00	997.00
IUUC-Sha-106845	Sarcophilus harrisii	62.55	0.00e+00	853.00
IUUC-Sly-111123	Solanum lycopersicum	45.10	3.00e-09	55.80
IUUC-Stu-112434	Solanum tuberosum	45.10	3.00e-09	55.80
IUUC-Sar-113420	Sorex araneus	66.88	0.00e+00	980.00
IUUC-Ssc-115679	Sus scrofa	68.60	0.00e+00	922.00
IUUC-Tgu-117069	Taeniopygia guttata	73.17	0.00e+00	1102.00
IUUC-Tru-118488	Takifugu rubripes	60.21	0.00e+00	892.00
IUUC-Tsy-119243	Tarsius syrichta	62.60	0.00e+00	719.00
IUUC-Tni-120584	Tetraodon nigroviridis	63.96	0.00e+00	967.00
IUUC-Tre-121917	Trichoderma reesei	40.00	7.00e-12	66.60
IUUC-Tbe-127994	Tupaia belangeri	55.28	0.00e+00	820.00
IUUC-Ttr-128839	Tursiops truncatus	67.40	0.00e+00	1010.00
IUUC-Vpa-130144	Vicugna pacos	63.58	0.00e+00	918.00
IUUC-Xtr-132624	Xenopus tropicalis	68.53	0.00e+00	1069.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence