iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-053395

UUCD1 version

UUC-LoA-00368

Ensembl Protein ID

ENSLAFP00000009079.2

UniProt Accession

G3T6D8; G3T6D8_LOXAF

Protein Name

Uncharacterized protein

Gene Name

RNF5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000010849.2	ENSLAFT00000010848.2	ENSLAFP00000009079.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	4.90e-07	30.5	35	76

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C iCle  ++  +v  CgH+++  Cl++w         ++ CP+C+
   Q: 35   CNICLETARE-AVVSVCGHLYCWPCLHQW---LETRPDRQECPVCK 76
           99******88.888***************...556889999****7 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

PGGEIESAMA AAEEEDGGPE GPNRERGGGG ATFECNICLE TAREAVVSVC GHLYCWPCLH 60
QWLETRPDRQ ECPVCKAGIS REKVVPLYGR GSQKPQDPRL KTPPRPQGQR PAPESRGGFQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCCGGGGGTG AAATAGAATC GGCAATGGCA GCAGCGGAGG AGGAGGACGG GGGCCCCGAA 60
GGGCCAAATC GTGAGCGGGG CGGGGGGGGC GCGACCTTCG AATGTAATAT ATGTTTGGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2

SMART

SM00184--RING

Gene Ontology

GO:0036513--C:Derlin-1 retrotranslocation complex
GO:0016021--C:integral component of membrane
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0071712--P:ER-associated misfolded protein catabolic process
GO:0010507--P:negative regulation of autophagy
GO:0031648--P:protein destabilization
GO:0070936--P:protein K48-linked ubiquitination
GO:0070534--P:protein K63-linked ubiquitination
GO:2000785--P:regulation of autophagosome assembly
GO:0009617--P:response to bacterium

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001155	Aegilops tauschii	48.54	5.00e-24	104.00
IUUC-Aml-001417	Ailuropoda melanoleuca	95.35	6.00e-70	256.00
IUUC-Aca-004254	Anolis carolinensis	77.01	2.00e-36	144.00
IUUC-Ame-011316	Astyanax mexicanus	70.73	1.00e-57	215.00
IUUC-Bta-013109	Bos taurus	96.45	1.00e-77	281.00
IUUC-Bdi-014313	Brachypodium distachyon	54.65	2.00e-23	102.00
IUUC-Bra-017631	Brassica rapa	48.62	1.00e-26	112.00
IUUC-Cja-019902	Callithrix jacchus	95.74	1.00e-76	278.00
IUUC-Cfa-020079	Canis familiaris	95.74	1.00e-76	278.00
IUUC-Cpo-021320	Cavia porcellus	91.25	1.00e-81	295.00
IUUC-Csa-023595	Chlorocebus sabaeus	95.74	3.00e-77	280.00
IUUC-Dre-027716	Danio rerio	73.33	2.00e-41	162.00
IUUC-Dno-029843	Dasypus novemcinctus	82.98	2.00e-54	204.00
IUUC-Dor-030170	Dipodomys ordii	98.39	1.00e-69	254.00
IUUC-Eca-033642	Equus caballus	96.18	3.00e-86	310.00
IUUC-Eeu-034778	Erinaceus europaeus	96.58	2.00e-62	230.00
IUUC-Fca-036326	Felis catus	95.74	1.00e-77	281.00
IUUC-Fso-038195	Fusarium solani	40.00	5.00e-10	58.90
IUUC-Gac-042258	Gasterosteus aculeatus	78.57	5.00e-55	206.00
IUUC-Ggo-045474	Gorilla gorilla	96.45	2.00e-77	281.00
IUUC-Hsa-046046	Homo sapiens	96.45	2.00e-77	281.00
IUUC-Hvu-047124	Hordeum vulgare	48.54	1.00e-23	103.00
IUUC-Itr-048037	Ictidomys tridecemlineatus	96.00	3.00e-82	296.00
IUUC-Lch-050367	Latimeria chalumnae	73.55	3.00e-46	176.00
IUUC-Lpe-051034	Leersia perrieri	45.26	3.00e-25	108.00
IUUC-Mcc-054833	Macaca mulatta	95.74	3.00e-77	280.00
IUUC-Meu-055984	Macropus eugenii	83.54	5.00e-35	140.00
IUUC-Mdo-062437	Monodelphis domestica	86.62	2.00e-77	280.00
IUUC-Mmu-064159	Mus musculus	97.89	6.00e-79	286.00
IUUC-Mac-065053	Musa acuminata	57.65	2.00e-23	102.00
IUUC-Mlu-067689	Myotis lucifugus	90.12	2.00e-81	294.00
IUUC-Nle-069705	Nomascus leucogenys	96.45	2.00e-77	281.00
IUUC-Opr-070392	Ochotona princeps	76.27	7.00e-20	89.40
IUUC-Ont-072482	Oreochromis niloticus	73.43	2.00e-57	214.00
IUUC-Ocu-074208	Oryctolagus cuniculus	96.45	4.00e-77	280.00
IUUC-Oba-075461	Oryza barthii	51.65	1.00e-23	103.00
IUUC-Obr-076382	Oryza brachyantha	56.98	1.00e-24	106.00
IUUC-Ogl-077553	Oryza glaberrima	57.29	1.00e-26	112.00
IUUC-Ogu-078463	Oryza glumaepatula	57.29	1.00e-26	112.00
IUUC-Oin-080177	Oryza indica	57.29	1.00e-26	112.00
IUUC-Olo-080378	Oryza longistaminata	54.65	2.00e-23	102.00
IUUC-Ome-081605	Oryza meridionalis	57.29	1.00e-26	112.00
IUUC-Oni-082458	Oryza nivara	57.29	3.00e-26	112.00
IUUC-Opu-083362	Oryza punctata	58.14	2.00e-25	109.00
IUUC-Oru-084757	Oryza rufipogon	56.00	4.00e-27	114.00
IUUC-Osa-086198	Oryza sativa	56.00	5.00e-27	114.00
IUUC-Ola-086507	Oryzias latipes	71.07	2.00e-60	224.00
IUUC-Olu-087623	Ostreococcus lucimarinus	50.00	9.00e-17	79.70
IUUC-Oga-088912	Otolemur garnettii	97.16	5.00e-78	283.00
IUUC-Oar-090284	Ovis aries	96.83	2.00e-69	254.00
IUUC-Ptr-090919	Pan troglodytes	96.83	3.00e-69	253.00
IUUC-Pan-092843	Papio anubis	95.74	3.00e-77	280.00
IUUC-Pfo-096818	Poecilia formosa	70.66	1.00e-57	215.00
IUUC-Pab-098244	Pongo abelii	95.74	4.00e-77	280.00
IUUC-Pop-099595	Populus trichocarpa	43.54	5.00e-27	114.00
IUUC-Pca-100319	Procavia capensis	97.89	5.00e-80	289.00
IUUC-Pva-102249	Pteropus vampyrus	91.49	1.00e-70	258.00
IUUC-Rno-106042	Rattus norvegicus	97.89	6.00e-79	286.00
IUUC-Smo-109079	Selaginella moellendorffii	55.22	9.00e-22	97.80
IUUC-Sit-109934	Setaria italica	54.65	3.00e-23	101.00
IUUC-Sly-110917	Solanum lycopersicum	47.66	6.00e-25	107.00
IUUC-Sbi-114275	Sorghum bicolor	54.65	4.00e-23	100.00
IUUC-Ssc-115934	Sus scrofa	97.16	5.00e-78	283.00
IUUC-Tru-118679	Takifugu rubripes	61.73	5.00e-23	99.80
IUUC-Tsy-119615	Tarsius syrichta	93.33	2.00e-70	257.00
IUUC-Tca-121830	Theobroma cacao	48.78	1.00e-25	109.00
IUUC-Tae-124655	Triticum aestivum	48.54	7.00e-24	103.00
IUUC-Tur-126198	Triticum urartu	48.54	8.00e-24	103.00
IUUC-Tbe-127773	Tupaia belangeri	94.33	3.00e-74	270.00
IUUC-Ttr-128690	Tursiops truncatus	94.87	1.00e-61	228.00
IUUC-Vvi-131225	Vitis vinifera	60.00	1.00e-25	108.00
IUUC-Xtr-132608	Xenopus tropicalis	80.83	2.00e-45	174.00
IUUC-Xma-134225	Xiphophorus maculatus	68.45	2.00e-56	211.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence