iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Lch-049686

Ensembl Protein ID

ENSLACP00000002955.1

UniProt Accession

H2ZZY4; H2ZZY4_LATCH

Genbank Protein ID

ENSLACP00000002955

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AFYH01247752

Gene Name

SOCS5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLACG00000002644.1	ENSLACT00000002980.1	ENSLACP00000002955.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	5.40e-14	52.0	476	522

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box

   S: 4    lwllrseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlyedyq 53
            +l r+ p+SLq++CR +I+++++++++   d+LPLP+ L+d+L++++y+
   Q: 476  VPLNRTFPFSLQYICRAVICSHTTYDGI---DALPLPSILQDFLKEYHYK 522
           5678999*********************...****************985 PP

Organism

Latimeria chalumnae

Protein Sequence
(Fasta)

MDKVAKMWNN LKYRCQNLFS HENGHQSDNL DVNSYRCSLD KDKTLGSCDL PQQQPSSPLR 60
DNPAISTVLL NASQSSIRRN QNCVSEIPQV VEVTVEKENE ELCAATGTRL ARRDSYSRHA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGATAAAG TAGCAAAGAT GTGGAACAAC TTGAAATATA GATGCCAAAA CCTTTTCAGC 60
CATGAAAATG GACATCAAAG TGACAATCTT GATGTAAACT CTTATAGGTG CTCTTTGGAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000980--SH2
IPR022252--SOCS4/SOCS5_dom
IPR028420--SOCS5
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2
PF12610--SOCS
PF07525--SOCS_box

SMART

SM00252--SH2
SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0005622--C:intracellular
GO:0007173--P:epidermal growth factor receptor signaling pathway
GO:0007259--P:JAK-STAT cascade
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0016567--P:protein ubiquitination

KEGG

lcm:102352925

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000371	Aegilops tauschii	34.69	1.10e-02	32.70
IUUC-Apl-003815	Anas platyrhynchos	80.89	0.00e+00	880.00
IUUC-Aca-004504	Anolis carolinensis	77.68	0.00e+00	774.00
IUUC-Ame-010677	Astyanax mexicanus	62.96	0.00e+00	640.00
IUUC-Bta-012338	Bos taurus	79.59	0.00e+00	841.00
IUUC-Cja-019828	Callithrix jacchus	79.59	0.00e+00	825.00
IUUC-Cfa-020369	Canis familiaris	78.85	0.00e+00	838.00
IUUC-Cpo-021397	Cavia porcellus	78.85	0.00e+00	856.00
IUUC-Csa-023856	Chlorocebus sabaeus	79.22	0.00e+00	839.00
IUUC-Dre-028262	Danio rerio	63.24	2.00e-168	585.00
IUUC-Dno-029019	Dasypus novemcinctus	79.59	0.00e+00	867.00
IUUC-Dme-031965	Drosophila melanogaster	68.60	7.00e-71	261.00
IUUC-Ete-032972	Echinops telfairi	58.99	3.00e-99	354.00
IUUC-Eca-033867	Equus caballus	79.78	0.00e+00	870.00
IUUC-Fca-035806	Felis catus	78.66	0.00e+00	842.00
IUUC-Fal-037117	Ficedula albicollis	80.52	0.00e+00	869.00
IUUC-Gmo-039066	Gadus morhua	84.33	3.00e-109	388.00
IUUC-Gga-040876	Gallus gallus	80.71	0.00e+00	861.00
IUUC-Gac-042149	Gasterosteus aculeatus	65.75	0.00e+00	630.00
IUUC-Ggo-045169	Gorilla gorilla	78.48	0.00e+00	836.00
IUUC-Hsa-045805	Homo sapiens	79.41	0.00e+00	840.00
IUUC-Itr-049048	Ictidomys tridecemlineatus	78.66	0.00e+00	855.00
IUUC-Loc-051745	Lepisosteus oculatus	70.72	0.00e+00	701.00
IUUC-Laf-054124	Loxodonta africana	79.41	0.00e+00	861.00
IUUC-Mcc-055175	Macaca mulatta	79.22	0.00e+00	839.00
IUUC-Meu-056557	Macropus eugenii	78.93	0.00e+00	857.00
IUUC-Mga-059214	Meleagris gallopavo	80.52	0.00e+00	877.00
IUUC-Mvi-060418	Microbotryum violaceum	30.86	9.00e-02	30.00
IUUC-Mmr-060613	Microcebus murinus	66.36	0.00e+00	644.00
IUUC-Mdo-062788	Monodelphis domestica	79.11	0.00e+00	830.00
IUUC-Mmu-064333	Mus musculus	78.66	0.00e+00	833.00
IUUC-Mpu-066048	Mustela putorius furo	79.41	0.00e+00	844.00
IUUC-Mlu-067430	Myotis lucifugus	79.22	0.00e+00	828.00
IUUC-Nle-069086	Nomascus leucogenys	79.22	0.00e+00	863.00
IUUC-Opr-070312	Ochotona princeps	77.92	0.00e+00	820.00
IUUC-Ont-072299	Oreochromis niloticus	64.10	0.00e+00	631.00
IUUC-Ocu-074123	Oryctolagus cuniculus	78.29	0.00e+00	823.00
IUUC-Ola-086934	Oryzias latipes	67.71	0.00e+00	657.00
IUUC-Oga-088535	Otolemur garnettii	80.15	0.00e+00	873.00
IUUC-Oar-089875	Ovis aries	79.59	0.00e+00	845.00
IUUC-Ptr-090541	Pan troglodytes	79.41	0.00e+00	840.00
IUUC-Pan-092416	Papio anubis	79.22	0.00e+00	839.00
IUUC-Psi-092960	Pelodiscus sinensis	78.29	0.00e+00	849.00
IUUC-Pma-094222	Petromyzon marinus	51.52	2.00e-133	469.00
IUUC-Pfo-096930	Poecilia formosa	63.29	0.00e+00	640.00
IUUC-Pab-098659	Pongo abelii	79.41	0.00e+00	841.00
IUUC-Pca-100222	Procavia capensis	76.81	0.00e+00	832.00
IUUC-Pva-102387	Pteropus vampyrus	79.41	0.00e+00	840.00
IUUC-Rno-105698	Rattus norvegicus	78.85	0.00e+00	833.00
IUUC-Sha-107234	Sarcophilus harrisii	78.56	0.00e+00	827.00
IUUC-Sar-113698	Sorex araneus	76.25	0.00e+00	760.00
IUUC-Ssc-115985	Sus scrofa	78.48	0.00e+00	854.00
IUUC-Tgu-116676	Taeniopygia guttata	80.33	0.00e+00	868.00
IUUC-Tru-118441	Takifugu rubripes	59.06	3.00e-148	518.00
IUUC-Tsy-119163	Tarsius syrichta	75.51	0.00e+00	814.00
IUUC-Tni-120436	Tetraodon nigroviridis	66.00	0.00e+00	630.00
IUUC-Tca-121131	Theobroma cacao	30.77	6.60e-02	31.60
IUUC-Tae-124846	Triticum aestivum	34.69	1.70e-02	32.30
IUUC-Tbe-127353	Tupaia belangeri	79.96	0.00e+00	845.00
IUUC-Ttr-128907	Tursiops truncatus	79.59	0.00e+00	827.00
IUUC-Vpa-130140	Vicugna pacos	79.96	0.00e+00	845.00
IUUC-Xtr-132817	Xenopus tropicalis	75.56	0.00e+00	807.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence