iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cpo-022253

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAKN02003305

Gene Name

TRIM35

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000000053.3	ENSCPOT00000000053.2	ENSCPOP00000000046.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	4.60e-10	39.4	16	85
E3 activity/RING/RING	1.90e-07	31.5	21	61

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 3    peeflCpIslelMrdPvvlpsGitydrssIekwlasggk.tcPvtrqplteedlvPnltlrrliqawcee 71
            ee+lC++ ++++rd v+l++G+ + r ++ ++ + + + tcPv++++ ++ dl  n+tl +l+++ + e
   Q: 16   KEELLCAVCFDPFRDAVTLQCGHNFCRGCVSRCWEVQTTpTCPVCKAHASPADLRTNHTLNNLVEKLLRE 85
           689******************************9888888***********************9987765 PP

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkwpglknssskefrCPlCr 46
           Ca+C+++f+d  ++l+CgH f++ C+  +w     + +++ +CP+C+
   Q: 21   CAVCFDPFRD-AVTLQCGHNFCRGCVsRCW-----EVQTTPTCPVCK 61
           *********9.999************9999.....899********7 PP

Organism

Cavia porcellus

Protein Sequence
(Fasta)

MEFSPVPLSG PAGSFKEELL CAVCFDPFRD AVTLQCGHNF CRGCVSRCWE VQTTPTCPVC 60
KAHASPADLR TNHTLNNLVE KLLREEAELG FFCLEDKELL CCLCQADPRH QGHRVQPVKD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGTTCA GTCCGGTGCC GTTGTCTGGG CCTGCTGGCT CCTTCAAGGA GGAGCTCCTC 60
TGCGCCGTCT GCTTCGATCC CTTCCGTGAC GCGGTGACGC TGCAGTGTGG CCACAACTTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR000315--Znf_B-box
IPR018957--Znf_C3HC4_RING-type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13765--PRY
PF00622--SPRY
PF00097--zf-C3HC4

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00589--PRY
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0005622--C:intracellular
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:0045930--P:negative regulation of mitotic cell cycle
GO:1902187--P:negative regulation of viral release from host cell
GO:0043065--P:positive regulation of apoptotic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001788	Ailuropoda melanoleuca	79.51	0.00e+00	817.00
IUUC-Apl-003958	Anas platyrhynchos	52.14	1.00e-127	449.00
IUUC-Aca-005199	Anolis carolinensis	45.01	9.00e-121	427.00
IUUC-Ame-011964	Astyanax mexicanus	33.54	4.00e-67	248.00
IUUC-Bta-013359	Bos taurus	78.96	0.00e+00	796.00
IUUC-Cja-018900	Callithrix jacchus	69.82	0.00e+00	695.00
IUUC-Cfa-020685	Canis familiaris	78.70	0.00e+00	811.00
IUUC-Csa-023777	Chlorocebus sabaeus	81.14	0.00e+00	832.00
IUUC-Dre-028677	Danio rerio	29.11	1.00e-59	223.00
IUUC-Dno-029065	Dasypus novemcinctus	77.11	0.00e+00	780.00
IUUC-Dor-030248	Dipodomys ordii	60.84	3.00e-94	337.00
IUUC-Ete-033183	Echinops telfairi	65.25	0.00e+00	634.00
IUUC-Eca-033263	Equus caballus	77.21	0.00e+00	710.00
IUUC-Eeu-034699	Erinaceus europaeus	72.38	2.00e-104	372.00
IUUC-Fca-036366	Felis catus	77.89	0.00e+00	802.00
IUUC-Fal-037257	Ficedula albicollis	54.85	5.00e-147	514.00
IUUC-Gmo-038512	Gadus morhua	33.12	4.00e-64	238.00
IUUC-Gga-041125	Gallus gallus	51.46	4.00e-100	357.00
IUUC-Gac-042136	Gasterosteus aculeatus	34.00	3.00e-68	252.00
IUUC-Ggo-045233	Gorilla gorilla	83.54	1.00e-160	558.00
IUUC-Hsa-046042	Homo sapiens	81.54	0.00e+00	834.00
IUUC-Itr-048751	Ictidomys tridecemlineatus	79.75	0.00e+00	798.00
IUUC-Lch-049548	Latimeria chalumnae	34.24	6.00e-79	288.00
IUUC-Loc-051729	Lepisosteus oculatus	33.68	1.00e-76	280.00
IUUC-Laf-054322	Loxodonta africana	79.50	0.00e+00	794.00
IUUC-Mcc-055555	Macaca mulatta	79.16	0.00e+00	813.00
IUUC-Meu-055900	Macropus eugenii	74.31	0.00e+00	737.00
IUUC-Mga-059380	Meleagris gallopavo	52.02	3.00e-94	338.00
IUUC-Mmr-061296	Microcebus murinus	78.90	0.00e+00	795.00
IUUC-Mdo-062811	Monodelphis domestica	74.42	0.00e+00	741.00
IUUC-Mmu-063718	Mus musculus	72.63	0.00e+00	724.00
IUUC-Mpu-066219	Mustela putorius furo	78.96	0.00e+00	791.00
IUUC-Mlu-067033	Myotis lucifugus	76.88	0.00e+00	784.00
IUUC-Nle-069806	Nomascus leucogenys	81.56	0.00e+00	781.00
IUUC-Opr-070248	Ochotona princeps	73.51	0.00e+00	703.00
IUUC-Ont-071392	Oreochromis niloticus	33.12	8.00e-63	234.00
IUUC-Oan-073364	Ornithorhynchus anatinus	58.69	1.00e-97	348.00
IUUC-Ocu-074572	Oryctolagus cuniculus	81.30	0.00e+00	833.00
IUUC-Oga-088378	Otolemur garnettii	77.28	0.00e+00	780.00
IUUC-Oar-089516	Ovis aries	78.54	0.00e+00	786.00
IUUC-Ptr-091313	Pan troglodytes	81.54	0.00e+00	834.00
IUUC-Pan-092877	Papio anubis	81.34	0.00e+00	833.00
IUUC-Psi-093928	Pelodiscus sinensis	57.77	5.00e-157	547.00
IUUC-Pfo-096690	Poecilia formosa	33.26	7.00e-66	244.00
IUUC-Pab-098624	Pongo abelii	81.34	0.00e+00	827.00
IUUC-Pca-100469	Procavia capensis	74.21	0.00e+00	746.00
IUUC-Pva-103227	Pteropus vampyrus	77.89	0.00e+00	802.00
IUUC-Rno-105778	Rattus norvegicus	72.43	0.00e+00	724.00
IUUC-Sha-107392	Sarcophilus harrisii	64.11	2.00e-180	625.00
IUUC-Sar-113297	Sorex araneus	68.55	7.00e-47	180.00
IUUC-Ssc-115739	Sus scrofa	78.33	0.00e+00	781.00
IUUC-Tru-117718	Takifugu rubripes	30.51	2.00e-59	223.00
IUUC-Tni-120490	Tetraodon nigroviridis	33.61	2.00e-67	249.00
IUUC-Tbe-127926	Tupaia belangeri	77.58	2.00e-125	442.00
IUUC-Ttr-129293	Tursiops truncatus	77.89	0.00e+00	793.00
IUUC-Vpa-130379	Vicugna pacos	79.19	1.00e-140	492.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence