iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

iUUCD ID

IUUC-Rno-105513

Ensembl Protein ID

ENSRNOP00000066186.2

UniProt Accession

M0R9L3; M0R9L3_RAT

Genbank Protein ID

ENSRNOP00000066186

Protein Name

Sorting nexin

Genbank Nucleotide ID

AABR07001481

Gene Name

Snx9

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSRNOG00000046874.2	ENSRNOT00000075268.2	ENSRNOP00000066186.2

Annotation

mRNA Expression
GEO
DNA & RNA Element
RAID2
Post-translational Modifications (PTMs)
CPLM
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	6.60e-11	42.4	3	59

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaq.nddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekl 62
           k +v+yd+ a+  ++eLt ++G+++++  + +  +gWl+g k+ +g +Gl+P ++ve l
   Q: 3    KARVMYDFAAEpGNNELTVNEGEIITIT-NPNVGGGWLEG-KNSKGEQGLVPTDYVEIL 59
           6789******95689************8.9**********.7**************865 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

VTKARVMYDF AAEPGNNELT VNEGEIITIT NPNVGGGWLE GKNSKGEQGL VPTDYVEILP 60
NDGKDPFSCG NSVADQAFLD SLSASTAQAN SSSANSNNQV GGGSDPWSAW NAPRSGNWDS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTCACCAAGG CCAGCATCTG TTTCTGACCA CATGAAGGGT GAGGCTTTTT CTTTCTTAGT 60
GAAGCAGGTG TGTTTGGGAT TGTGTTTTAG GATCAACCTC TATACATGCA GCATGTGCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0968--Cytoplasmic vesicle
KW-0472--Membrane
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR027267--AH/BAR-dom
IPR001683--Phox
IPR001452--SH3_domain
IPR028644--SNX9
IPR014536--Snx9_subfam
IPR019497--Sorting_nexin_WASP-bd-dom

PROSITE

PS50195--PX
PS50002--SH3

Pfam

PF10456--BAR_3_WASP_bdg
PF00787--PX
PF00018--SH3_1

SMART

SM00312--PX
SM00326--SH3

Gene Ontology

GO:0030136--C:clathrin-coated vesicle
GO:0031410--C:cytoplasmic vesicle
GO:0030659--C:cytoplasmic vesicle membrane
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0031234--C:extrinsic component of cytoplasmic side of plasma membrane
GO:0005802--C:trans-Golgi network
GO:0005545--F:1-phosphatidylinositol binding
GO:0036089--P:cleavage furrow formation
GO:0016197--P:endosomal transport
GO:0006886--P:intracellular protein transport
GO:0060988--P:lipid tube assembly
GO:0000281--P:mitotic cytokinesis
GO:0007067--P:mitotic nuclear division
GO:0097320--P:plasma membrane tubulation
GO:0043547--P:positive regulation of GTPase activity
GO:0051044--P:positive regulation of membrane protein ectodomain proteolysis
GO:0045860--P:positive regulation of protein kinase activity
GO:0032461--P:positive regulation of protein oligomerization
GO:0006898--P:receptor-mediated endocytosis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001493	Ailuropoda melanoleuca	89.34	0.00e+00	1048.00
IUUC-Apl-003889	Anas platyrhynchos	81.67	0.00e+00	971.00
IUUC-Ame-011163	Astyanax mexicanus	60.42	0.00e+00	724.00
IUUC-Bta-013027	Bos taurus	87.67	0.00e+00	1033.00
IUUC-Cel-018605	Caenorhabditis elegans	33.76	2.00e-61	230.00
IUUC-Cja-019428	Callithrix jacchus	86.87	0.00e+00	1043.00
IUUC-Cfa-021208	Canis familiaris	89.36	0.00e+00	1050.00
IUUC-Cpo-021353	Cavia porcellus	89.23	0.00e+00	1056.00
IUUC-Cho-025020	Choloepus hoffmanni	97.34	7.00e-156	543.00
IUUC-Cin-025695	Ciona intestinalis	39.59	5.00e-84	305.00
IUUC-Csv-025870	Ciona savignyi	34.05	1.00e-89	323.00
IUUC-Dre-027983	Danio rerio	60.19	0.00e+00	738.00
IUUC-Dme-031845	Drosophila melanogaster	37.60	3.00e-70	259.00
IUUC-Fca-036506	Felis catus	88.72	0.00e+00	1034.00
IUUC-Fal-037443	Ficedula albicollis	75.16	0.00e+00	921.00
IUUC-Gmo-039464	Gadus morhua	57.31	0.00e+00	637.00
IUUC-Gac-041835	Gasterosteus aculeatus	56.44	0.00e+00	648.00
IUUC-Ggo-045438	Gorilla gorilla	83.08	0.00e+00	978.00
IUUC-Hsa-046762	Homo sapiens	86.70	0.00e+00	1038.00
IUUC-Itr-048294	Ictidomys tridecemlineatus	88.34	0.00e+00	1043.00
IUUC-Lch-049906	Latimeria chalumnae	66.23	4.00e-164	570.00
IUUC-Loc-052748	Lepisosteus oculatus	63.85	0.00e+00	756.00
IUUC-Lma-053062	Leptosphaeria maculans	44.83	3.00e-06	47.00
IUUC-Laf-053373	Loxodonta africana	88.38	0.00e+00	1048.00
IUUC-Mcc-054953	Macaca mulatta	86.70	0.00e+00	1033.00
IUUC-Mga-059536	Meleagris gallopavo	80.63	0.00e+00	986.00
IUUC-Mmr-061000	Microcebus murinus	87.90	0.00e+00	1042.00
IUUC-Mdo-061885	Monodelphis domestica	82.89	0.00e+00	1000.00
IUUC-Mmu-063532	Mus musculus	91.92	0.00e+00	1095.00
IUUC-Mlu-067143	Myotis lucifugus	85.40	0.00e+00	1011.00
IUUC-Ont-072028	Oreochromis niloticus	62.82	0.00e+00	756.00
IUUC-Oan-073741	Ornithorhynchus anatinus	75.32	1.00e-56	211.00
IUUC-Ola-086919	Oryzias latipes	61.75	0.00e+00	743.00
IUUC-Oga-088465	Otolemur garnettii	87.88	0.00e+00	1006.00
IUUC-Oar-089562	Ovis aries	86.99	0.00e+00	1029.00
IUUC-Ptr-090632	Pan troglodytes	86.70	0.00e+00	1038.00
IUUC-Pan-092192	Papio anubis	86.70	0.00e+00	1029.00
IUUC-Psi-093346	Pelodiscus sinensis	80.70	0.00e+00	976.00
IUUC-Pma-094619	Petromyzon marinus	41.10	1.00e-76	280.00
IUUC-Pno-094868	Phaeosphaeria nodorum	44.83	3.00e-06	46.60
IUUC-Pfo-096634	Poecilia formosa	61.17	0.00e+00	741.00
IUUC-Pab-097866	Pongo abelii	86.97	0.00e+00	1036.00
IUUC-Pva-102273	Pteropus vampyrus	88.49	0.00e+00	1034.00
IUUC-Pte-104168	Pyrenophora teres	44.83	3.00e-06	46.60
IUUC-Pyt-104443	Pyrenophora triticirepentis	44.83	3.00e-06	46.60
IUUC-Ssc-116184	Sus scrofa	88.16	0.00e+00	1040.00
IUUC-Tgu-117370	Taeniopygia guttata	81.00	0.00e+00	990.00
IUUC-Tru-117764	Takifugu rubripes	60.10	0.00e+00	722.00
IUUC-Tni-119947	Tetraodon nigroviridis	63.70	0.00e+00	757.00
IUUC-Ttr-128700	Tursiops truncatus	84.18	0.00e+00	987.00
IUUC-Xtr-132466	Xenopus tropicalis	67.17	0.00e+00	776.00
IUUC-Xma-134033	Xiphophorus maculatus	61.13	0.00e+00	723.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence