iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Apl-003910

Ensembl Protein ID

ENSAPLP00000006316.1

UniProt Accession

U3IGE4; U3IGE4_ANAPL

Genbank Protein ID

ENSAPLP00000006316

Protein Name

Inhibitor of growth protein

Genbank Nucleotide ID

ADON01148359

Gene Name

ING1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAPLG00000006713.1	ENSAPLT00000006959.1	ENSAPLP00000006316.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	3.60e-09	36.4	220	267

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCek..Cr.ewfHpaClklsveeelpnsekwiCpkCrs 53
           ++C +C + + +e  ++ C++  C  ewfH+ C++l+    +p+ + w+CpkCr 
   Q: 220  TYC-LCNQVSYGE--MIGCDNdeCPiEWFHFSCVGLN---HKPKGK-WYCPKCRG 267
           69*.*******99..******9**99***********...999997.******85 PP

Organism

Anas platyrhynchos

Protein Sequence
(Fasta)

LLLPSRRMKM LSPANGEQLH LVNYVEDYLD SIESMPFDLQ RNVSLMREID AKYQEILKDL 60
DDYYEKFKRE TDAVQKRRML HCIQRALIRS QELGDEKIQI VSQMVELVEN RTRQVDSHVE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTCCTCCTTC CTTCTCGCCG GATGAAAATG TTGAGTCCTG CGAACGGCGA GCAGCTGCAC 60
CTCGTGAACT ATGTGGAGGA TTACCTGGAC TCCATCGAGT CGATGCCCTT CGATCTGCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR028643--ING1
IPR028651--ING_fam
IPR024610--ING_N_histone_binding
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF12998--ING

SMART

SM01408--ING
SM00249--PHD

Gene Ontology

GO:0005634--C:nucleus
GO:0008270--F:zinc ion binding
GO:0016569--P:covalent chromatin modification
GO:0008285--P:negative regulation of cell proliferation
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0006606--P:protein import into nucleus
GO:0010941--P:regulation of cell death

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001945	Ailuropoda melanoleuca	93.88	2.00e-129	454.00
IUUC-Aca-004874	Anolis carolinensis	95.34	4.00e-130	456.00
IUUC-Aly-005815	Arabidopsis lyrata	80.00	1.00e-28	119.00
IUUC-Acl-008091	Aspergillus clavatus	52.11	7.00e-19	89.00
IUUC-Ame-011262	Astyanax mexicanus	67.13	2.00e-95	342.00
IUUC-Bta-013507	Bos taurus	88.84	3.00e-92	330.00
IUUC-Cja-018925	Callithrix jacchus	90.65	7.00e-124	436.00
IUUC-Cfa-020947	Canis familiaris	93.88	8.00e-129	452.00
IUUC-Cpo-022286	Cavia porcellus	91.06	2.00e-99	355.00
IUUC-Csa-023825	Chlorocebus sabaeus	90.29	2.00e-123	434.00
IUUC-Cho-024577	Choloepus hoffmanni	93.97	1.00e-100	358.00
IUUC-Cne-027005	Cryptococcus neoformans	47.76	5.00e-16	78.20
IUUC-Dre-028562	Danio rerio	58.82	6.00e-75	273.00
IUUC-Dno-029834	Dasypus novemcinctus	94.96	2.00e-130	457.00
IUUC-Dor-030315	Dipodomys ordii	90.13	2.00e-109	388.00
IUUC-Ete-032408	Echinops telfairi	91.03	6.00e-96	343.00
IUUC-Eca-034244	Equus caballus	93.56	2.00e-102	364.00
IUUC-Fca-035391	Felis catus	88.03	2.00e-109	387.00
IUUC-Fal-036838	Ficedula albicollis	98.93	7.00e-138	482.00
IUUC-Fox-037925	Fusarium oxysporum	69.57	1.00e-19	90.50
IUUC-Gmo-038748	Gadus morhua	54.51	2.00e-76	278.00
IUUC-Gga-040619	Gallus gallus	98.58	5.00e-138	483.00
IUUC-Gac-041996	Gasterosteus aculeatus	63.96	3.00e-97	347.00
IUUC-Ggo-045481	Gorilla gorilla	87.66	1.00e-96	346.00
IUUC-Hsa-046170	Homo sapiens	87.66	1.00e-96	346.00
IUUC-Itr-048440	Ictidomys tridecemlineatus	95.71	5.00e-104	369.00
IUUC-Lch-050397	Latimeria chalumnae	89.93	7.00e-126	442.00
IUUC-Loc-052038	Lepisosteus oculatus	79.46	4.00e-100	357.00
IUUC-Laf-054126	Loxodonta africana	95.32	8.00e-131	459.00
IUUC-Mcc-055031	Macaca mulatta	88.03	4.00e-96	344.00
IUUC-Meu-056248	Macropus eugenii	94.94	4.00e-106	377.00
IUUC-Mga-059217	Meleagris gallopavo	97.42	3.00e-107	380.00
IUUC-Mmr-061581	Microcebus murinus	94.63	5.00e-108	382.00
IUUC-Mdo-062452	Monodelphis domestica	96.04	8.00e-133	465.00
IUUC-Mmu-063412	Mus musculus	92.45	9.00e-127	445.00
IUUC-Mpu-066479	Mustela putorius furo	93.56	2.00e-102	365.00
IUUC-Mlu-067586	Myotis lucifugus	80.00	3.00e-118	417.00
IUUC-Nle-069122	Nomascus leucogenys	89.93	8.00e-123	432.00
IUUC-Opr-070835	Ochotona princeps	83.62	1.00e-82	298.00
IUUC-Ont-071606	Oreochromis niloticus	60.66	2.00e-90	325.00
IUUC-Oan-073023	Ornithorhynchus anatinus	93.17	3.00e-126	444.00
IUUC-Ocu-073779	Oryctolagus cuniculus	87.45	3.00e-93	333.00
IUUC-Ola-086891	Oryzias latipes	65.23	4.00e-97	347.00
IUUC-Olu-087851	Ostreococcus lucimarinus	69.23	9.00e-20	89.70
IUUC-Oga-087954	Otolemur garnettii	92.09	2.00e-126	444.00
IUUC-Oar-090006	Ovis aries	89.93	5.00e-123	432.00
IUUC-Ptr-090589	Pan troglodytes	90.29	2.00e-123	434.00
IUUC-Pan-091896	Papio anubis	88.03	2.00e-96	345.00
IUUC-Psi-093266	Pelodiscus sinensis	96.79	1.00e-134	471.00
IUUC-Pma-094265	Petromyzon marinus	71.95	1.00e-34	138.00
IUUC-Pfo-096633	Poecilia formosa	56.44	3.00e-71	261.00
IUUC-Pab-098253	Pongo abelii	90.29	3.00e-123	434.00
IUUC-Pva-102753	Pteropus vampyrus	83.33	2.00e-91	328.00
IUUC-Rno-105964	Rattus norvegicus	91.42	1.00e-90	325.00
IUUC-Sha-107270	Sarcophilus harrisii	95.68	1.00e-131	461.00
IUUC-Tgu-116822	Taeniopygia guttata	99.28	5.00e-137	479.00
IUUC-Tru-118262	Takifugu rubripes	56.35	3.00e-77	281.00
IUUC-Tni-119980	Tetraodon nigroviridis	57.84	6.00e-84	303.00
IUUC-Tre-121950	Trichoderma reesei	64.29	2.00e-19	90.50
IUUC-Tvi-122341	Trichoderma virens	62.50	3.00e-16	77.40
IUUC-Ttr-128672	Tursiops truncatus	91.03	1.00e-99	355.00
IUUC-Xtr-132200	Xenopus tropicalis	86.33	2.00e-118	418.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence