iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Laf-054126

Ensembl Protein ID

ENSLAFP00000024544.1

UniProt Accession

G3U9N6; G3U9N6_LOXAF

Protein Name

Inhibitor of growth protein

Gene Name

ING1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000032747.1	ENSLAFT00000025593.1	ENSLAFP00000024544.1
ENSLAFG00000032747.1	ENSLAFT00000027517.1	ENSLAFP00000021507.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	6.10e-09	36.3	211	258

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCek..Cr.ewfHpaClklsveeelpnsekwiCpkCrs 53
           ++C +C + + +e  ++ C++  C  ewfH+ C++l+    +p+ + w+CpkCr 
   Q: 211  TYC-LCNQVSYGE--MIGCDNdeCPiEWFHFSCVGLN---HKPKGK-WYCPKCRG 258
           69*.*******99..******9**99***********...999997.******85 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MLSPANGEQI HLVNYVEDYL DSIESLPFDL QRNVSLMREI DAKYQEILKE LDDYYERFKR 60
ETDGTQKRRV LHCIQRALIR SQELGDEKIQ IVSQMVELVE NRTRQVDSHV ELFEAHQEIS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTTGAGTC CTGCAAACGG GGAGCAGATC CACCTGGTGA ACTATGTGGA GGATTATCTG 60
GACTCCATCG AGTCTTTGCC TTTCGACCTG CAGAGAAACG TCTCGCTGAT GAGGGAGATA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR028643--ING1
IPR028651--ING_fam
IPR024610--ING_N_histone_binding
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF12998--ING

SMART

SM01408--ING
SM00249--PHD

Gene Ontology

GO:0005634--C:nucleus
GO:0008270--F:zinc ion binding
GO:0016569--P:covalent chromatin modification
GO:0008285--P:negative regulation of cell proliferation
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0006606--P:protein import into nucleus
GO:0010941--P:regulation of cell death

KEGG

lav:100655373

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001945	Ailuropoda melanoleuca	96.06	7.00e-134	469.00
IUUC-Apl-003910	Anas platyrhynchos	95.32	7.00e-131	459.00
IUUC-Aca-004874	Anolis carolinensis	93.93	3.00e-128	450.00
IUUC-Ame-011262	Astyanax mexicanus	67.93	2.00e-96	345.00
IUUC-Bta-013507	Bos taurus	90.60	1.00e-94	338.00
IUUC-Cja-018925	Callithrix jacchus	91.76	5.00e-127	446.00
IUUC-Cfa-020947	Canis familiaris	95.70	2.00e-132	464.00
IUUC-Cpo-022286	Cavia porcellus	93.64	3.00e-104	371.00
IUUC-Csa-023825	Chlorocebus sabaeus	91.40	1.00e-126	445.00
IUUC-Cho-024577	Choloepus hoffmanni	97.85	5.00e-107	379.00
IUUC-Cne-027005	Cryptococcus neoformans	45.95	2.00e-16	79.30
IUUC-Dre-028562	Danio rerio	59.19	1.00e-75	275.00
IUUC-Dno-029834	Dasypus novemcinctus	97.85	2.00e-135	474.00
IUUC-Dor-030315	Dipodomys ordii	92.31	3.00e-113	401.00
IUUC-Ete-032408	Echinops telfairi	94.47	7.00e-102	363.00
IUUC-Eca-034244	Equus caballus	96.58	5.00e-108	383.00
IUUC-Fca-035391	Felis catus	90.35	6.00e-113	399.00
IUUC-Fal-036838	Ficedula albicollis	94.27	4.00e-130	457.00
IUUC-Fox-037925	Fusarium oxysporum	69.57	1.00e-19	90.90
IUUC-Gmo-038748	Gadus morhua	55.26	3.00e-77	281.00
IUUC-Gga-040619	Gallus gallus	94.62	4.00e-130	456.00
IUUC-Gac-041996	Gasterosteus aculeatus	64.89	1.00e-96	345.00
IUUC-Ggo-045481	Gorilla gorilla	88.98	1.00e-99	356.00
IUUC-Hsa-046170	Homo sapiens	88.98	1.00e-99	356.00
IUUC-Itr-048440	Ictidomys tridecemlineatus	97.44	1.00e-107	381.00
IUUC-Lch-050397	Latimeria chalumnae	89.96	4.00e-125	440.00
IUUC-Loc-052038	Lepisosteus oculatus	81.01	4.00e-101	360.00
IUUC-Mcc-055031	Macaca mulatta	89.36	3.00e-99	355.00
IUUC-Meu-056248	Macropus eugenii	94.12	2.00e-104	372.00
IUUC-Mga-059217	Meleagris gallopavo	93.56	9.00e-102	362.00
IUUC-Mmr-061581	Microcebus murinus	96.71	8.00e-113	399.00
IUUC-Mdo-062452	Monodelphis domestica	96.42	2.00e-132	464.00
IUUC-Mmu-063412	Mus musculus	96.42	2.00e-133	468.00
IUUC-Mpu-066479	Mustela putorius furo	95.30	3.00e-106	377.00
IUUC-Mlu-067586	Myotis lucifugus	81.85	2.00e-122	431.00
IUUC-Nle-069122	Nomascus leucogenys	91.04	7.00e-126	442.00
IUUC-Opr-070835	Ochotona princeps	86.70	3.00e-88	317.00
IUUC-Ont-071606	Oreochromis niloticus	61.76	8.00e-92	330.00
IUUC-Oan-073023	Ornithorhynchus anatinus	93.19	7.00e-127	446.00
IUUC-Ocu-073779	Oryctolagus cuniculus	90.42	1.00e-98	352.00
IUUC-Ola-086891	Oryzias latipes	66.07	1.00e-97	349.00
IUUC-Oga-087954	Otolemur garnettii	95.70	5.00e-133	466.00
IUUC-Oar-090006	Ovis aries	92.47	6.00e-128	449.00
IUUC-Ptr-090589	Pan troglodytes	91.40	2.00e-126	444.00
IUUC-Pan-091896	Papio anubis	89.36	2.00e-99	355.00
IUUC-Psi-093266	Pelodiscus sinensis	95.34	2.00e-131	461.00
IUUC-Pma-094265	Petromyzon marinus	75.34	7.00e-34	135.00
IUUC-Pfo-097531	Poecilia formosa	61.69	3.00e-94	338.00
IUUC-Pab-098253	Pongo abelii	91.40	2.00e-126	444.00
IUUC-Pva-102753	Pteropus vampyrus	85.71	1.00e-96	346.00
IUUC-Rno-105964	Rattus norvegicus	94.87	6.00e-95	339.00
IUUC-Sha-107270	Sarcophilus harrisii	95.70	7.00e-131	459.00
IUUC-Tgu-116822	Taeniopygia guttata	94.62	2.00e-130	458.00
IUUC-Tru-118262	Takifugu rubripes	57.47	1.00e-78	285.00
IUUC-Tni-119980	Tetraodon nigroviridis	57.65	2.00e-83	301.00
IUUC-Tre-121950	Trichoderma reesei	64.29	2.00e-19	91.30
IUUC-Tvi-122341	Trichoderma virens	62.50	3.00e-16	77.40
IUUC-Ttr-128672	Tursiops truncatus	93.62	2.00e-104	371.00
IUUC-Xtr-132200	Xenopus tropicalis	86.02	9.00e-118	416.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence