iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
miRNAMap	RAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
dbPAF	PhosphositePlus
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/SCF/F-box	88.63	0.00e+00	715.00	IUUC-Hsa-046558

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MSHSGPPRPG AAPSRPAWLV PAGRAETEAE RLGNRCARPC LAEPAAMAGS EPRGAGSPPP 60
ASDWGRLEAA ILSGWRTFWN SVGKERATRT ASRKEEAEET SALTRLPIDV QLYILSFLSP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGTCAGCCAA GGTCAATGTC ATTAATAACA GATGGGACTT TTTGGAGCAC TTTAGTTCCA 60
CAGGCTCTTG ATCGTCTCCA TGTTTTTGCT AAACTCCAGT AAAGCGGTAG ATTGCTGATT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR001810--F-box_dom

PROSITE

PS50181--FBOX

Pfam

PF12937--F-box-like

SMART

SM00256--FBOX

Gene Ontology

GO:0005737--C:cytoplasm
GO:0019005--C:SCF ubiquitin ligase complex
GO:0061630--F:ubiquitin protein ligase activity
GO:0007568--P:aging
GO:0019725--P:cellular homeostasis
GO:0071479--P:cellular response to ionizing radiation
GO:0035726--P:common myeloid progenitor cell proliferation
GO:0048147--P:negative regulation of fibroblast proliferation
GO:1900181--P:negative regulation of protein localization to nucleus
GO:1902916--P:positive regulation of protein polyubiquitination
GO:0010608--P:posttranscriptional regulation of gene expression
GO:0031648--P:protein destabilization
GO:0000209--P:protein polyubiquitination
GO:2000001--P:regulation of DNA damage checkpoint
GO:0031146--P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

KEGG

rno:310363

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001232	Ailuropoda melanoleuca	91.06	0.00e+00	685.00
IUUC-Apl-004129	Anas platyrhynchos	62.07	2.00e-109	388.00
IUUC-Aca-005076	Anolis carolinensis	48.68	3.00e-109	388.00
IUUC-Aly-005608	Arabidopsis lyrata	33.85	1.00e-02	34.30
IUUC-Ath-007114	Arabidopsis thaliana	33.33	4.00e-03	35.40
IUUC-Ame-011122	Astyanax mexicanus	47.02	5.00e-85	307.00
IUUC-Bta-012449	Bos taurus	88.11	0.00e+00	672.00
IUUC-Bol-015278	Brassica oleracea	22.56	2.00e-03	36.60
IUUC-Cja-019890	Callithrix jacchus	88.89	0.00e+00	693.00
IUUC-Cfa-021134	Canis familiaris	89.92	0.00e+00	680.00
IUUC-Cpo-021693	Cavia porcellus	89.51	2.00e-169	588.00
IUUC-Csa-023540	Chlorocebus sabaeus	88.37	0.00e+00	677.00
IUUC-Dre-028667	Danio rerio	47.55	4.00e-86	311.00
IUUC-Dno-028997	Dasypus novemcinctus	89.62	0.00e+00	667.00
IUUC-Dor-030135	Dipodomys ordii	80.81	2.00e-155	541.00
IUUC-Ete-033149	Echinops telfairi	84.01	0.00e+00	638.00
IUUC-Eca-033292	Equus caballus	91.67	6.00e-175	606.00
IUUC-Eeu-034504	Erinaceus europaeus	73.15	1.00e-129	455.00
IUUC-Fca-036476	Felis catus	90.70	0.00e+00	732.00
IUUC-Fal-036711	Ficedula albicollis	63.36	2.00e-120	425.00
IUUC-Gmo-039592	Gadus morhua	48.62	1.00e-86	313.00
IUUC-Gga-040924	Gallus gallus	61.85	2.00e-121	428.00
IUUC-Gac-041791	Gasterosteus aculeatus	50.93	4.00e-85	308.00
IUUC-Ggo-044736	Gorilla gorilla	88.37	0.00e+00	673.00
IUUC-Hsa-046558	Homo sapiens	88.11	0.00e+00	675.00
IUUC-Itr-048956	Ictidomys tridecemlineatus	89.41	0.00e+00	681.00
IUUC-Lch-049817	Latimeria chalumnae	64.53	8.00e-128	449.00
IUUC-Loc-052226	Lepisosteus oculatus	50.95	1.00e-105	375.00
IUUC-Laf-054371	Loxodonta africana	88.11	0.00e+00	677.00
IUUC-Mcc-054904	Macaca mulatta	88.11	0.00e+00	676.00
IUUC-Meu-056192	Macropus eugenii	54.94	1.00e-89	322.00
IUUC-Mmr-061692	Microcebus murinus	88.37	0.00e+00	692.00
IUUC-Mdo-062666	Monodelphis domestica	76.23	2.00e-160	558.00
IUUC-Mmu-064223	Mus musculus	96.10	0.00e+00	773.00
IUUC-Mpu-066290	Mustela putorius furo	89.92	0.00e+00	679.00
IUUC-Mlu-067882	Myotis lucifugus	88.11	0.00e+00	677.00
IUUC-Nle-070162	Nomascus leucogenys	88.63	0.00e+00	680.00
IUUC-Opr-070789	Ochotona princeps	86.30	6.00e-75	274.00
IUUC-Ont-071690	Oreochromis niloticus	44.68	6.00e-80	291.00
IUUC-Oan-072928	Ornithorhynchus anatinus	72.31	2.00e-112	398.00
IUUC-Ocu-073857	Oryctolagus cuniculus	91.33	0.00e+00	654.00
IUUC-Ogu-078061	Oryza glumaepatula	30.26	5.60e-01	31.20
IUUC-Oni-083091	Oryza nivara	30.65	7.70e-01	30.40
IUUC-Ola-086607	Oryzias latipes	45.57	1.00e-86	313.00
IUUC-Oga-088929	Otolemur garnettii	90.16	0.00e+00	652.00
IUUC-Oar-089305	Ovis aries	91.98	3.00e-176	610.00
IUUC-Ptr-090813	Pan troglodytes	84.24	0.00e+00	641.00
IUUC-Pan-092924	Papio anubis	87.19	2.00e-177	614.00
IUUC-Psi-093237	Pelodiscus sinensis	65.96	5.00e-130	457.00
IUUC-Pfo-096259	Poecilia formosa	46.61	2.00e-87	315.00
IUUC-Pab-098292	Pongo abelii	88.63	0.00e+00	680.00
IUUC-Pva-102221	Pteropus vampyrus	90.70	0.00e+00	707.00
IUUC-Sha-106998	Sarcophilus harrisii	76.15	1.00e-160	559.00
IUUC-Sar-113033	Sorex araneus	79.46	7.00e-172	596.00
IUUC-Sbi-113808	Sorghum bicolor	26.00	2.00e-04	39.70
IUUC-Ssc-115507	Sus scrofa	88.11	0.00e+00	643.00
IUUC-Tgu-116502	Taeniopygia guttata	62.76	2.00e-117	415.00
IUUC-Tru-118203	Takifugu rubripes	47.65	5.00e-76	278.00
IUUC-Tni-120249	Tetraodon nigroviridis	45.70	5.00e-79	287.00
IUUC-Tbe-128100	Tupaia belangeri	66.20	4.00e-121	427.00
IUUC-Ttr-128299	Tursiops truncatus	80.36	2.00e-177	614.00
IUUC-Vpa-130394	Vicugna pacos	77.00	2.00e-161	561.00
IUUC-Xtr-131825	Xenopus tropicalis	54.67	1.00e-119	422.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence