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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Ath-007255
Ensembl Protein ID AT3G55360.1
UniProt Accession Q9M2U2; TECR_ARATH
Genbank Protein ID CAB75894.1; AEE79372.1; AAL38312.1; AAM10145.1; AAM65988.1
Protein Name Very-long-chain enoyl-CoA reductase; Enoyl-CoA reductase; Protein ECERIFERUM 10; Synaptic glycoprotein SC2-like protein
Genbank Nucleotide ID AL132975; CP002686; AY065136; AY081583; AY088452
Gene Name ECR; AtTSC13; CER10; At3g55360; T22E16.20
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
AT3G55360 AT3G55360.1 AT3G55360.1
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
TRANSFAC
Protein-protein Interaction
Mentha
Post-translational Modifications (PTMs)
dbPPT
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
ULD/UDP/UBQ/UBQ_Other 34.07 3.00e-35 143.00 IUUC-Spo-108110
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Arabidopsis thaliana
Functional Description
(View)

Functional Description


     Catalyzes the last of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme reduces the trans-2,3-enoyl-CoA fatty acid intermediate to an acyl-CoA that can be further elongated by entering a new cycle of elongation. Thereby, it participates in the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. Required for the elongation of fatty acids precursors of sphingolipids, storage lipids and cuticular waxes.
 Catalyzes the last of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme reduces the trans-2,3-enoyl-CoA fatty acid intermediate to an acyl-CoA that can be further elongated by entering a new cycle of elongation. Thereby, it participates in the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. Required for the elongation of fatty acids precursors of sphingolipids, storage lipids and cuticular waxes.
Protein Sequence
(Fasta)
MKVTVVSRSG REVLKAPLDL PDSATVADLQ EAFHKRAKKF YPSRQRLTLP VTPGSKDKPV 60
VLNSKKSLKE YCDGNNNSLT VVFKDLGAQV SYRTLFFFEY LGPLLIYPVF YYFPVYKFLG 120
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Protein Fasta Sequence


>IUUC-Ath-007255|ULD,UBQ_Other|Arabidopsis thaliana
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Nucleotide Sequence
(Fasta)
AACAAATGTT TTTGTTTGGA GTAAAAACCA AAAAAAAAAT GATGGGGAGC AACTAAAAAT 60
GTAAAATGGT CCCAATCTAA TCGCATAAGT TGGGAAGATA GTTAGTAGTT CTCCTACTCC 120
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Nucleotide Fasta Sequence


>IUUC-Ath-007255|ULD,UBQ_Other|Arabidopsis thaliana
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Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0256--Endoplasmic reticulum
KW-0275--Fatty acid biosynthesis
KW-0276--Fatty acid metabolism
KW-0444--Lipid biosynthesis
KW-0443--Lipid metabolism
KW-0472--Membrane
KW-0521--NADP
KW-0560--Oxidoreductase
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
Interpro

IPR001104--3-oxo-5_a-steroid_4-DH_C
PROSITE

PS50244--S5A_REDUCTASE
Pfam

PF02544--Steroid_dh
Gene Ontology

GO:0005783--C:endoplasmic reticulum
GO:0005789--C:endoplasmic reticulum membrane
GO:0009923--C:fatty acid elongase complex
GO:0016021--C:integral component of membrane
GO:0005886--C:plasma membrane
GO:0009922--F:fatty acid elongase activity
GO:0016627--F:oxidoreductase activity, acting on the CH-CH group of donors
GO:0042335--P:cuticle development
GO:0006665--P:sphingolipid metabolic process
GO:0010091--P:trichome branching
GO:1905499--P:trichome papilla formation
GO:0042761--P:very long-chain fatty acid biosynthetic process
GO:0010025--P:wax biosynthetic process
KEGG ath:AT3G55360
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000125 Aegilops tauschii 80.44 2.00e-134 470.00
IUUC-Aml-001579 Ailuropoda melanoleuca 42.15 2.00e-48 185.00
IUUC-Atr-002693 Amborella trichopoda 74.83 5.00e-124 436.00
IUUC-Apl-004113 Anas platyrhynchos 36.68 3.00e-47 181.00
IUUC-Aca-004681 Anolis carolinensis 41.14 3.00e-54 204.00
IUUC-Aly-005795 Arabidopsis lyrata 97.10 2.00e-174 603.00
IUUC-Ago-007822 Ashbya gossypii 26.23 1.00e-20 92.80
IUUC-Acl-008131 Aspergillus clavatus 35.35 6.00e-32 130.00
IUUC-Afl-008670 Aspergillus flavus 31.12 3.00e-26 111.00
IUUC-Afu-009058 Aspergillus fumigatus 34.92 2.00e-30 125.00
IUUC-Ani-009299 Aspergillus nidulans 36.73 5.00e-28 117.00
IUUC-Ang-009520 Aspergillus niger 34.18 2.00e-29 122.00
IUUC-Aor-010023 Aspergillus oryzae 34.29 7.00e-37 146.00
IUUC-Ate-010593 Aspergillus terreus 33.12 9.00e-31 126.00
IUUC-Ame-011087 Astyanax mexicanus 39.60 3.00e-52 197.00
IUUC-Bgr-012251 Blumeria graminis 31.02 4.00e-32 130.00
IUUC-Bta-013170 Bos taurus 39.93 3.00e-52 198.00
IUUC-Bci-013894 Botrytis cinerea 32.82 3.00e-38 151.00
IUUC-Bdi-015014 Brachypodium distachyon 81.91 6.00e-149 519.00
IUUC-Bol-015761 Brassica oleracea 96.77 5.00e-174 602.00
IUUC-Bra-016894 Brassica rapa 96.45 1.00e-173 600.00
IUUC-Cel-018599 Caenorhabditis elegans 37.32 1.00e-49 189.00
IUUC-Cja-019333 Callithrix jacchus 39.26 1.00e-48 186.00
IUUC-Cfa-020709 Canis familiaris 39.93 4.00e-52 197.00
IUUC-Cpo-022353 Cavia porcellus 39.60 6.00e-52 196.00
IUUC-Cre-023020 Chlamydomonas reinhardtii 49.35 2.00e-85 308.00
IUUC-Csa-023716 Chlorocebus sabaeus 39.93 5.00e-52 197.00
IUUC-Csv-025915 Ciona savignyi 37.04 7.00e-52 196.00
IUUC-Cgl-026580 Colletotrichum gloeosporioides 36.55 1.00e-34 139.00
IUUC-Cne-027086 Cryptococcus neoformans 33.23 5.00e-31 127.00
IUUC-Cme-027185 Cyanidioschyzon merolae 44.04 1.00e-57 216.00
IUUC-Dre-028710 Danio rerio 39.60 2.00e-52 198.00
IUUC-Dno-029631 Dasypus novemcinctus 31.56 5.00e-37 147.00
IUUC-Dor-030220 Dipodomys ordii 39.93 2.00e-52 198.00
IUUC-Dse-031218 Dothistroma septosporum 34.75 2.00e-38 152.00
IUUC-Dme-031792 Drosophila melanogaster 38.76 8.00e-45 173.00
IUUC-Ete-032441 Echinops telfairi 47.68 4.00e-30 124.00
IUUC-Eca-033372 Equus caballus 39.93 4.00e-52 197.00
IUUC-Eeu-035351 Erinaceus europaeus 33.33 3.00e-31 127.00
IUUC-Fca-035630 Felis catus 39.93 4.00e-52 197.00
IUUC-Fal-037646 Ficedula albicollis 37.55 6.00e-38 150.00
IUUC-Fox-037721 Fusarium oxysporum 30.70 4.00e-28 117.00
IUUC-Fso-038379 Fusarium solani 30.25 4.00e-31 127.00
IUUC-Gmo-039616 Gadus morhua 42.24 1.00e-50 192.00
IUUC-Ggr-039727 Gaeumannomyces graminis 30.86 2.00e-34 138.00
IUUC-Gga-040786 Gallus gallus 39.03 2.00e-39 155.00
IUUC-Gac-041971 Gasterosteus aculeatus 36.79 7.00e-47 180.00
IUUC-Gma-043815 Glycine max 81.29 3.00e-142 497.00
IUUC-Ggo-045138 Gorilla gorilla 32.42 2.00e-33 135.00
IUUC-Hsa-045822 Homo sapiens 39.93 4.00e-52 197.00
IUUC-Hvu-047496 Hordeum vulgare 82.13 1.00e-147 514.00
IUUC-Itr-048022 Ictidomys tridecemlineatus 40.65 3.00e-48 184.00
IUUC-Kpa-049334 Komagataella pastoris 29.81 5.00e-29 120.00
IUUC-Lch-050175 Latimeria chalumnae 38.49 5.00e-49 187.00
IUUC-Lpe-051290 Leersia perrieri 80.44 6.00e-135 472.00
IUUC-Loc-052055 Lepisosteus oculatus 39.47 1.00e-52 199.00
IUUC-Lma-053284 Leptosphaeria maculans 34.84 4.00e-39 154.00
IUUC-Laf-053677 Loxodonta africana 40.27 2.00e-52 198.00
IUUC-Mcc-055371 Macaca mulatta 37.79 7.00e-47 180.00
IUUC-Meu-056786 Macropus eugenii 38.13 4.00e-43 167.00
IUUC-Mor-057062 Magnaporthe oryzae 28.48 8.00e-31 126.00
IUUC-Mpo-057319 Magnaporthe poae 31.40 2.00e-34 138.00
IUUC-Mtr-058159 Medicago truncatula 81.35 8.00e-142 495.00
IUUC-Mla-058998 Melampsora laricipopulina 32.48 2.00e-31 129.00
IUUC-Mga-059715 Meleagris gallopavo 36.99 1.00e-47 182.00
IUUC-Mvi-060498 Microbotryum violaceum 34.95 5.00e-34 137.00
IUUC-Mmr-061604 Microcebus murinus 40.27 3.00e-52 197.00
IUUC-Mdo-062723 Monodelphis domestica 40.13 6.00e-53 200.00
IUUC-Mmu-064423 Mus musculus 44.20 6.00e-47 180.00
IUUC-Mac-064557 Musa acuminata 79.35 7.00e-146 508.00
IUUC-Mpu-065790 Mustela putorius furo 39.93 5.00e-52 197.00
IUUC-Mlu-067323 Myotis lucifugus 39.93 2.00e-52 198.00
IUUC-Nfi-068303 Neosartorya fischeri 35.11 2.00e-32 131.00
IUUC-Ncr-068930 Neurospora crassa 31.53 1.00e-32 132.00
IUUC-Nle-069641 Nomascus leucogenys 39.93 5.00e-52 197.00
IUUC-Opr-070264 Ochotona princeps 33.15 2.00e-23 102.00
IUUC-Ont-072619 Oreochromis niloticus 39.60 4.00e-52 197.00
IUUC-Oan-072871 Ornithorhynchus anatinus 40.80 6.00e-54 203.00
IUUC-Ocu-074116 Oryctolagus cuniculus 31.68 6.00e-39 154.00
IUUC-Oba-075519 Oryza barthii 79.59 2.00e-144 504.00
IUUC-Obr-076026 Oryza brachyantha 79.52 3.00e-144 503.00
IUUC-Ogl-077299 Oryza glaberrima 80.41 7.00e-146 508.00
IUUC-Ogu-078328 Oryza glumaepatula 79.93 3.00e-133 467.00
IUUC-Oin-079058 Oryza indica 80.41 7.00e-146 508.00
IUUC-Olo-080760 Oryza longistaminata 79.92 2.00e-120 424.00
IUUC-Ome-081290 Oryza meridionalis 79.59 2.00e-144 504.00
IUUC-Oni-082116 Oryza nivara 73.80 2.00e-140 491.00
IUUC-Opu-083484 Oryza punctata 79.59 3.00e-143 500.00
IUUC-Oru-085234 Oryza rufipogon 73.80 2.00e-140 491.00
IUUC-Osa-085723 Oryza sativa 80.41 7.00e-146 508.00
IUUC-Ola-087142 Oryzias latipes 38.93 2.00e-51 195.00
IUUC-Olu-087663 Ostreococcus lucimarinus 55.67 1.00e-91 328.00
IUUC-Oga-088511 Otolemur garnettii 39.93 3.00e-52 197.00
IUUC-Oar-090337 Ovis aries 47.17 9.00e-38 149.00
IUUC-Ptr-090829 Pan troglodytes 39.73 2.00e-51 195.00
IUUC-Pan-091853 Papio anubis 40.22 4.00e-47 181.00
IUUC-Psi-093244 Pelodiscus sinensis 45.31 8.00e-49 186.00
IUUC-Pno-094768 Phaeosphaeria nodorum 35.57 9.00e-40 157.00
IUUC-Ppa-095402 Physcomitrella patens 55.31 5.00e-106 376.00
IUUC-Pfo-096308 Poecilia formosa 39.27 6.00e-52 197.00
IUUC-Pab-098622 Pongo abelii 39.69 6.00e-44 169.00
IUUC-Pop-099770 Populus trichocarpa 82.58 3.00e-147 513.00
IUUC-Pca-100732 Procavia capensis 40.27 8.00e-53 199.00
IUUC-Ppe-102094 Prunus persica 81.61 2.00e-155 540.00
IUUC-Pva-103208 Pteropus vampyrus 39.93 4.00e-52 197.00
IUUC-Pgr-103639 Puccinia graminis 25.71 2.00e-18 85.50
IUUC-Ptt-103851 Puccinia triticina 30.77 2.00e-27 115.00
IUUC-Pte-104134 Pyrenophora teres 37.16 2.00e-43 168.00
IUUC-Pyt-104660 Pyrenophora triticirepentis 36.91 5.00e-44 170.00
IUUC-Rno-104826 Rattus norvegicus 39.60 2.00e-51 195.00
IUUC-Sce-106237 Saccharomyces cerevisiae 31.17 8.00e-31 126.00
IUUC-Sha-107453 Sarcophilus harrisii 40.47 7.00e-54 203.00
IUUC-Sja-107686 Schizosaccharomyces japonicus 34.29 4.00e-37 147.00
IUUC-Spo-108110 Schizosaccharomyces pombe 34.07 1.00e-37 149.00
IUUC-Smo-108765 Selaginella moellendorffii 68.27 1.00e-123 435.00
IUUC-Sit-110416 Setaria italica 82.26 8.00e-158 549.00
IUUC-Sly-111184 Solanum lycopersicum 80.97 2.00e-157 547.00
IUUC-Stu-112187 Solanum tuberosum 81.29 1.00e-157 547.00
IUUC-Sar-113576 Sorex araneus 35.63 3.00e-09 55.10
IUUC-Sbi-114251 Sorghum bicolor 81.94 6.00e-158 548.00
IUUC-Sre-114975 Sporisorium reilianum 35.91 1.00e-44 172.00
IUUC-Ssc-115522 Sus scrofa 42.15 4.00e-48 184.00
IUUC-Tgu-116610 Taeniopygia guttata 38.33 2.00e-45 175.00
IUUC-Tru-118204 Takifugu rubripes 39.26 3.00e-52 197.00
IUUC-Tsy-119153 Tarsius syrichta 28.19 3.00e-29 122.00
IUUC-Tni-119738 Tetraodon nigroviridis 38.49 9.00e-51 192.00
IUUC-Tca-120950 Theobroma cacao 83.55 2.00e-160 557.00
IUUC-Tre-122109 Trichoderma reesei 32.41 2.00e-35 142.00
IUUC-Tvi-122473 Trichoderma virens 32.11 1.00e-34 139.00
IUUC-Tae-123617 Triticum aestivum 81.57 2.00e-148 517.00
IUUC-Tur-126035 Triticum urartu 79.41 2.00e-115 408.00
IUUC-Tme-127040 Tuber melanosporum 31.56 2.00e-28 119.00
IUUC-Tbe-127888 Tupaia belangeri 31.30 6.00e-13 67.80
IUUC-Ttr-128486 Tursiops truncatus 39.93 2.00e-52 198.00
IUUC-Uma-129516 Ustilago maydis 36.65 1.00e-45 176.00
IUUC-Vda-129861 Verticillium dahliae 31.44 3.00e-28 118.00
IUUC-Vpa-130704 Vicugna pacos 29.38 2.00e-34 139.00
IUUC-Vvi-131375 Vitis vinifera 81.29 3.00e-158 550.00
IUUC-Xtr-132795 Xenopus tropicalis 40.79 2.00e-53 201.00
IUUC-Xma-133866 Xiphophorus maculatus 38.94 1.00e-51 196.00
IUUC-Yli-134568 Yarrowia lipolytica 31.78 6.00e-36 144.00
IUUC-Zma-134891 Zea mays 80.44 3.00e-154 537.00
Created Date 25-Jun-2017

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