iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Bta-012516

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

DAAA02020220

Gene Name

CDC34

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000002098.4	ENSBTAT00000002707.4	ENSBTAP00000002707.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	4.50e-48	162.7	18	156

Active Site

Position(s)	Description	Evidence
96	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 4    kelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilk..... 87
            elk l+++p+eg+++++vde dl++wev+i+Gp++t+Yegg+Fk++++fp dYP++PP ++fltk++hPn+ye+G+vC+sil+     
   Q: 18   LELKGLQEEPVEGFRVTLVDEGDLYNWEVAIFGPPNTYYEGGYFKARLKFPIDYPYSPPAFRFLTKMWHPNIYETGDVCISILHppvdd 106
           599********************************************************************************999999 PP
   S: 88   ......eeekWspalsvesvllsiqsllaepnpesplneeaaellkknre 131
                 ++e+W+p+++v+++lls++sll+epn+ sp+n++a+ +++k++e
   Q: 107  pqsgelPSERWNPTQNVRTILLSVISLLNEPNTFSPANVDASVMYRKWKE 156
           999*9******************************************998 PP

Organism

Bos taurus

Protein Sequence
(Fasta)

AAAMARPLVP SSQKALLLEL KGLQEEPVEG FRVTLVDEGD LYNWEVAIFG PPNTYYEGGY 60
FKARLKFPID YPYSPPAFRF LTKMWHPNIY ETGDVCISIL HPPVDDPQSG ELPSERWNPT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCCGCCGCCA TGGCCCGGCC GCTGGTGCCC AGCTCGCAGA AGGCGTTGTT GCTGGAGCTC 60
AAGGGGCTGC AAGAGGAGCC GGTGGAGGGC TTCCGGGTGA CCCTGGTGGA CGAGGGCGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0016607--C:nuclear speck
GO:0005524--F:ATP binding
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0031625--F:ubiquitin protein ligase binding
GO:0035458--P:cellular response to interferon-beta
GO:0043951--P:negative regulation of cAMP-mediated signaling
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0070936--P:protein K48-linked ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001600	Ailuropoda melanoleuca	98.68	1.00e-130	458.00
IUUC-Ate-010563	Aspergillus terreus	42.53	1.00e-36	145.00
IUUC-Ame-011425	Astyanax mexicanus	87.02	2.00e-108	384.00
IUUC-Cja-018852	Callithrix jacchus	89.52	4.00e-103	367.00
IUUC-Cfa-020203	Canis familiaris	99.51	2.00e-120	424.00
IUUC-Cpo-022139	Cavia porcellus	92.48	1.00e-121	428.00
IUUC-Csa-023371	Chlorocebus sabaeus	94.64	5.00e-121	426.00
IUUC-Dre-028367	Danio rerio	89.05	4.00e-108	383.00
IUUC-Dor-030875	Dipodomys ordii	94.67	1.00e-121	428.00
IUUC-Fca-035832	Felis catus	97.59	2.00e-93	333.00
IUUC-Gmo-039414	Gadus morhua	90.05	2.00e-109	387.00
IUUC-Gga-040694	Gallus gallus	91.95	2.00e-121	427.00
IUUC-Gac-042485	Gasterosteus aculeatus	88.06	8.00e-109	385.00
IUUC-Ggo-044806	Gorilla gorilla	94.71	7.00e-123	432.00
IUUC-Hsa-046245	Homo sapiens	94.64	5.00e-121	426.00
IUUC-Lch-049845	Latimeria chalumnae	90.05	2.00e-109	387.00
IUUC-Loc-052932	Lepisosteus oculatus	86.90	2.00e-111	394.00
IUUC-Mcc-054665	Macaca mulatta	91.07	4.00e-114	403.00
IUUC-Mga-060075	Meleagris gallopavo	90.76	2.00e-121	427.00
IUUC-Mmr-061165	Microcebus murinus	95.52	3.00e-121	427.00
IUUC-Mdo-061825	Monodelphis domestica	99.03	7.00e-120	422.00
IUUC-Mmu-064168	Mus musculus	99.51	2.00e-120	424.00
IUUC-Mpu-066009	Mustela putorius furo	98.66	5.00e-129	452.00
IUUC-Opr-070826	Ochotona princeps	90.23	7.00e-109	386.00
IUUC-Ont-071745	Oreochromis niloticus	89.66	2.00e-110	391.00
IUUC-Oan-073287	Ornithorhynchus anatinus	89.83	9.00e-117	412.00
IUUC-Ocu-074902	Oryctolagus cuniculus	95.63	2.00e-116	411.00
IUUC-Ola-086976	Oryzias latipes	88.89	1.00e-107	382.00
IUUC-Oga-088845	Otolemur garnettii	96.90	3.00e-127	447.00
IUUC-Ptr-090916	Pan troglodytes	94.17	3.00e-117	414.00
IUUC-Pan-092577	Papio anubis	94.64	5.00e-121	426.00
IUUC-Psi-093039	Pelodiscus sinensis	89.33	4.00e-87	313.00
IUUC-Pfo-096435	Poecilia formosa	89.05	2.00e-109	388.00
IUUC-Pab-098200	Pongo abelii	94.15	6.00e-110	389.00
IUUC-Pca-100169	Procavia capensis	85.71	2.00e-65	241.00
IUUC-Pva-102875	Pteropus vampyrus	99.32	1.00e-84	304.00
IUUC-Rno-106079	Rattus norvegicus	99.51	2.00e-120	424.00
IUUC-Ssc-115699	Sus scrofa	92.43	2.00e-90	324.00
IUUC-Tgu-117466	Taeniopygia guttata	89.83	3.00e-119	421.00
IUUC-Tru-117589	Takifugu rubripes	83.90	3.00e-103	367.00
IUUC-Tni-120864	Tetraodon nigroviridis	86.07	3.00e-105	374.00
IUUC-Xtr-132285	Xenopus tropicalis	85.71	2.00e-115	407.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence