iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Details
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

iUUCD ID

IUUC-Cel-018460

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

UBiquitin Conjugating enzyme

Genbank Nucleotide ID

BX284601

Gene Name

ubc-3; CELE_Y71G12B.15; Y71G12B.15

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
WBGene00006702	Y71G12B.15a.1	Y71G12B.15a.1

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
microRNA	RAID2
Protein-protein Interaction
IID
Protein Expression/Proteomics

Status

Reviewed

Details

Family	Domain	References (PMIDs)
E2/UBC	E2_UBC	15530417

Classification

Family	E-value	Score	Start	End
E2/UBC	9.60e-47	158.5	15	155

Active Site

Position(s)	Description	Evidence
94	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 2    lkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilk.......... 87
           l+ elk+l+++p+eg++++++++ +l+ w v i Gp++t Y+gg+Fk++i+fp++YP++PP++kf+tk++hPnvyenG++C+sil+          
   Q: 15   LTMELKNLQSQPVEGFTIDVNED-NLFVWTVGIYGPPKTLYQGGYFKASIRFPSNYPYSPPSMKFTTKVWHPNVYENGDLCISILHspiddpqsge 109
           5679*******************.9************************************************************98999999999 PP
   S: 88   .eeekWspalsvesvllsiqsllaepnpesplneeaaellkknree 132
              e+W+p++sv+++lls++sll+epn++sp+n++a+ +++k++e+
   Q: 110  lACERWNPTQSVRTILLSVISLLNEPNTSSPANVDASVMYRKWKED 155
           999**********************************999998873 PP

Organism

Caenorhabditis elegans

Protein Sequence
(Fasta)

MDSKASTSSG ALRALTMELK NLQSQPVEGF TIDVNEDNLF VWTVGIYGPP KTLYQGGYFK 60
ASIRFPSNYP YSPPSMKFTT KVWHPNVYEN GDLCISILHS PIDDPQSGEL ACERWNPTQS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGTCGCTTCG TTCAGTGTGT GTGTGTGTGT TTGCCATTTC TCTGCGTTTC CGTCGCACTC 60
TTTCCTCTCT TCAGCACCAC CAGTGTCAGA CTCTTCTCTC CAACCTTTCC TCTTCCTTCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005524--F:ATP binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0031625--F:ubiquitin protein ligase binding
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process

KEGG

cel:CELE_Y71G12B.15

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001600	Ailuropoda melanoleuca	64.14	2.00e-72	264.00
IUUC-Apl-003563	Anas platyrhynchos	66.90	2.00e-57	213.00
IUUC-Aca-004589	Anolis carolinensis	65.13	6.00e-76	275.00
IUUC-Acl-008052	Aspergillus clavatus	52.02	5.00e-39	152.00
IUUC-Afl-008620	Aspergillus flavus	50.00	3.00e-36	143.00
IUUC-Ani-009262	Aspergillus nidulans	46.97	2.00e-39	154.00
IUUC-Ang-009716	Aspergillus niger	56.43	8.00e-35	139.00
IUUC-Aor-009930	Aspergillus oryzae	50.00	3.00e-36	143.00
IUUC-Ate-010563	Aspergillus terreus	48.69	2.00e-40	157.00
IUUC-Ame-011425	Astyanax mexicanus	66.49	7.00e-74	268.00
IUUC-Bta-012968	Bos taurus	66.31	7.00e-74	268.00
IUUC-Cja-018764	Callithrix jacchus	65.97	2.00e-75	273.00
IUUC-Cfa-020955	Canis familiaris	65.97	2.00e-75	273.00
IUUC-Cpo-021451	Cavia porcellus	65.97	2.00e-75	273.00
IUUC-Csa-024239	Chlorocebus sabaeus	65.97	2.00e-75	273.00
IUUC-Cin-025344	Ciona intestinalis	65.41	2.00e-73	267.00
IUUC-Csv-025954	Ciona savignyi	64.65	2.00e-75	273.00
IUUC-Dre-028367	Danio rerio	65.45	4.00e-74	269.00
IUUC-Dno-029368	Dasypus novemcinctus	66.31	7.00e-74	268.00
IUUC-Dor-030686	Dipodomys ordii	65.97	2.00e-75	273.00
IUUC-Dme-032106	Drosophila melanogaster	69.57	5.00e-76	276.00
IUUC-Eca-034221	Equus caballus	67.36	3.00e-57	213.00
IUUC-Fca-036381	Felis catus	67.12	7.00e-58	214.00
IUUC-Fal-037135	Ficedula albicollis	65.97	4.00e-75	272.00
IUUC-Gmo-039565	Gadus morhua	65.13	7.00e-75	271.00
IUUC-Gga-040477	Gallus gallus	65.46	3.00e-75	273.00
IUUC-Gac-041909	Gasterosteus aculeatus	64.68	1.00e-74	271.00
IUUC-Ggo-045150	Gorilla gorilla	65.97	2.00e-75	273.00
IUUC-Hsa-046611	Homo sapiens	65.97	2.00e-75	273.00
IUUC-Itr-047984	Ictidomys tridecemlineatus	57.07	2.00e-63	233.00
IUUC-Kpa-049316	Komagataella pastoris	42.69	4.00e-32	129.00
IUUC-Lch-050173	Latimeria chalumnae	64.04	5.00e-75	272.00
IUUC-Loc-052932	Lepisosteus oculatus	64.92	2.00e-73	266.00
IUUC-Laf-053860	Loxodonta africana	65.97	2.00e-75	273.00
IUUC-Mcc-054820	Macaca mulatta	65.97	2.00e-75	273.00
IUUC-Meu-056681	Macropus eugenii	58.97	7.00e-68	248.00
IUUC-Mga-060075	Meleagris gallopavo	65.45	3.00e-73	266.00
IUUC-Mmr-060666	Microcebus murinus	65.97	2.00e-75	273.00
IUUC-Mdo-062804	Monodelphis domestica	64.04	3.00e-75	273.00
IUUC-Mmu-063472	Mus musculus	65.97	2.00e-75	273.00
IUUC-Mpu-066009	Mustela putorius furo	64.14	2.00e-72	263.00
IUUC-Mlu-067163	Myotis lucifugus	65.13	2.00e-72	263.00
IUUC-Nfi-068322	Neosartorya fischeri	50.61	8.00e-37	145.00
IUUC-Nle-070152	Nomascus leucogenys	74.07	1.00e-46	176.00
IUUC-Opr-070826	Ochotona princeps	64.57	1.00e-63	234.00
IUUC-Ont-071627	Oreochromis niloticus	66.32	5.00e-75	272.00
IUUC-Oan-073287	Ornithorhynchus anatinus	65.45	1.00e-73	267.00
IUUC-Ocu-074229	Oryctolagus cuniculus	66.14	2.00e-74	270.00
IUUC-Ola-086587	Oryzias latipes	65.13	8.00e-75	271.00
IUUC-Oga-089161	Otolemur garnettii	66.31	7.00e-74	268.00
IUUC-Oar-089383	Ovis aries	65.97	2.00e-75	273.00
IUUC-Ptr-091096	Pan troglodytes	65.97	2.00e-75	273.00
IUUC-Pan-092560	Papio anubis	66.31	7.00e-74	268.00
IUUC-Psi-093263	Pelodiscus sinensis	67.36	5.00e-57	212.00
IUUC-Pma-094368	Petromyzon marinus	68.28	4.00e-57	211.00
IUUC-Pfo-096974	Poecilia formosa	63.18	9.00e-75	271.00
IUUC-Pab-098344	Pongo abelii	65.97	2.00e-75	273.00
IUUC-Pca-100169	Procavia capensis	65.38	4.00e-46	176.00
IUUC-Pva-102875	Pteropus vampyrus	67.61	1.00e-54	204.00
IUUC-Rno-105821	Rattus norvegicus	65.97	2.00e-75	273.00
IUUC-Sha-107364	Sarcophilus harrisii	64.04	3.00e-75	273.00
IUUC-Sar-112992	Sorex araneus	63.54	4.00e-69	252.00
IUUC-Ssc-115699	Sus scrofa	64.33	1.00e-57	214.00
IUUC-Tgu-117074	Taeniopygia guttata	65.97	4.00e-75	272.00
IUUC-Tru-118641	Takifugu rubripes	64.32	6.00e-74	268.00
IUUC-Tsy-118797	Tarsius syrichta	67.91	2.00e-53	199.00
IUUC-Tni-119817	Tetraodon nigroviridis	64.18	2.00e-74	270.00
IUUC-Tme-127042	Tuber melanosporum	48.23	2.00e-34	137.00
IUUC-Tbe-128014	Tupaia belangeri	65.97	2.00e-75	273.00
IUUC-Ttr-129037	Tursiops truncatus	66.48	1.00e-70	257.00
IUUC-Vpa-130680	Vicugna pacos	67.61	2.00e-56	209.00
IUUC-Xtr-131819	Xenopus tropicalis	67.96	2.00e-73	267.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence