iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cpo-021343

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAKN02007164

Gene Name

USP30

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000013022.3	ENSCPOT00000013148.2	ENSCPOP00000011722.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	6.80e-72	242.4	92	524

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw...kskkkavsprellkalkkeaeefsgy 87
           Gl NlgNtC+mNS+LQ Ls++p + + l e +++ ++++ ++ p+++l+ +l +l+++l     +++++ + + ll++l+++  ++s++
   Q: 92   GLVNLGNTCFMNSLLQGLSACPAFIRWLEEFTTQYTRDQREPPPHQHLSLTLLHLLKALScqeVTEDEVLDASCLLDVLRMYRWQISSF 180
           9*****************************77777777778899***************888899999********************* PP
   S: 88   eqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde..........aeekkkkknkslisdlFqgqlksqikclecdnvs.sr 165
           e+qDa+E+++++ ++le+e    ++ +++++++ ++ e+++e          + + ++++n+   ++ F+g+l+s+++c++c+++s +r
   Q: 181  EEQDAHELFHVITSSLEDER--DRQPRVTHLFDVHSLEQQSEitpkqitcrtRGSPHPMSNHWKSQHPFHGRLTSNMVCKHCEHQSpVR 267
           *******************9..668888889998888888888999999999999********************************** PP
   S: 166  eepfldlslpvpgkeetkkeslqdcLesftkeeelegenkyycekck...............kkqeaekklklkklPevLilhLkRfsf 239
           +++f +lsl++p  +  ++++l++cL++f + e++++   + c++c+               ++++ +k+lkl klP++L++hL+R s+
   Q: 268  FDTFDSLSLSIPAATWGHPLTLDHCLHHFISSESVRD---VVCDNCTkieakgalnrekvehQRTTFVKQLKLGKLPQCLCIHLQRLSW 353
           ***********************************97...9******8888888888888777777*********************** PP
   S: 240  seeqksrekinkkvefpleLdlspfcts...............................peekqke....................... 274
           s++ + + k +++v+f++ L ++ +  +                               p     +                       
   Q: 354  SSH-GTPLKRHEHVQFNEFLMMDIYKYRllghkpsqpnaklsenpravlelqdgpsapkP-----Vlnqpggpktqifmngacspsllp 436
           998.8888*********9888886666666777777666666655555555555555550.....055555555555566666666666 PP
   S: 275  ...................kkkYeLiavvvHsGslssGHYvayvkn.........ekgkWllfdDskVtevkeeevleetgstaYvlfY 335
                              ++ ++L+avvvH+G ++sGH+v+y ++         ++++Wl ++D++V++ + +evl+   s+aY+lfY
   Q: 437  tltptmpfplpavpdysssTYLFRLMAVVVHHGDMHSGHFVTYRRSppstkhpfsTSNQWLWISDDTVRKASLQEVLS---SSAYLLFY 522
           66666666666666666559999***********************9999888888999*******************...******** PP
   S: 336  kr 337
           +r
   Q: 523  ER 524
           98 PP

Organism

Cavia porcellus

Protein Sequence
(Fasta)

LSVRLPRRRR RWRGRRRASR AAAMLRSRAE AAMTAADRAI QRFLRAGAAV RYKVMKNWGV 60
IGGIAAALAA GIYVIWGPIT ERKKRRKGLV PGLVNLGNTC FMNSLLQGLS ACPAFIRWLE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTCTCGGTCC GGCTTCCACG GAGGCGGCGG AGGTGGCGTG GGCGGCGACG GGCCTCCCGC 60
GCTGCCGCGA TGCTGCGCTC CCGGGCCGAG GCGGCGATGA CAGCGGCTGA CAGGGCCATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0005741--C:mitochondrial outer membrane
GO:0004197--F:cysteine-type endopeptidase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008053--P:mitochondrial fusion
GO:0000422--P:mitophagy
GO:0035871--P:protein K11-linked deubiquitination
GO:0044313--P:protein K6-linked deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000204	Aegilops tauschii	26.56	7.00e-18	85.10
IUUC-Aml-001733	Ailuropoda melanoleuca	90.52	0.00e+00	837.00
IUUC-Atr-002510	Amborella trichopoda	26.16	2.00e-20	94.40
IUUC-Apl-003645	Anas platyrhynchos	71.84	2.00e-106	378.00
IUUC-Aca-004583	Anolis carolinensis	68.42	1.00e-24	103.00
IUUC-Aly-005754	Arabidopsis lyrata	24.79	4.00e-23	102.00
IUUC-Ath-007622	Arabidopsis thaliana	27.07	5.00e-25	108.00
IUUC-Ame-010896	Astyanax mexicanus	62.32	5.00e-155	540.00
IUUC-Bgr-012133	Blumeria graminis	22.73	5.00e-11	63.20
IUUC-Bta-012321	Bos taurus	89.82	0.00e+00	834.00
IUUC-Bdi-014795	Brachypodium distachyon	27.60	2.00e-18	87.00
IUUC-Bol-015637	Brassica oleracea	27.45	4.00e-22	99.40
IUUC-Bra-016801	Brassica rapa	23.90	2.00e-18	86.70
IUUC-Cel-018308	Caenorhabditis elegans	27.69	7.00e-38	151.00
IUUC-Cja-018826	Callithrix jacchus	93.01	0.00e+00	904.00
IUUC-Cfa-021206	Canis familiaris	89.36	0.00e+00	853.00
IUUC-Csa-023419	Chlorocebus sabaeus	93.39	0.00e+00	907.00
IUUC-Cho-024475	Choloepus hoffmanni	86.55	3.00e-133	468.00
IUUC-Cgl-026621	Colletotrichum gloeosporioides	21.60	8.00e-13	68.90
IUUC-Cne-027061	Cryptococcus neoformans	24.90	5.00e-10	59.70
IUUC-Dre-027563	Danio rerio	59.07	2.00e-158	552.00
IUUC-Dno-029929	Dasypus novemcinctus	90.47	0.00e+00	873.00
IUUC-Dor-030166	Dipodomys ordii	81.52	0.00e+00	728.00
IUUC-Dme-031627	Drosophila melanogaster	34.48	9.00e-35	141.00
IUUC-Ete-032634	Echinops telfairi	78.40	0.00e+00	673.00
IUUC-Eca-033968	Equus caballus	92.04	0.00e+00	827.00
IUUC-Eeu-035279	Erinaceus europaeus	82.93	9.00e-59	221.00
IUUC-Fca-036525	Felis catus	91.63	0.00e+00	873.00
IUUC-Fal-036606	Ficedula albicollis	74.87	4.00e-159	553.00
IUUC-Gmo-038726	Gadus morhua	56.39	7.00e-142	497.00
IUUC-Gga-040718	Gallus gallus	75.19	3.00e-162	564.00
IUUC-Gac-042645	Gasterosteus aculeatus	57.68	5.00e-152	530.00
IUUC-Gma-042890	Glycine max	26.18	4.00e-26	112.00
IUUC-Ggo-045021	Gorilla gorilla	93.39	0.00e+00	904.00
IUUC-Hsa-045832	Homo sapiens	93.39	0.00e+00	904.00
IUUC-Itr-048392	Ictidomys tridecemlineatus	94.29	0.00e+00	852.00
IUUC-Lch-050662	Latimeria chalumnae	70.13	6.00e-178	617.00
IUUC-Lpe-051078	Leersia perrieri	26.61	3.00e-30	126.00
IUUC-Loc-052611	Lepisosteus oculatus	65.16	2.00e-177	615.00
IUUC-Lma-053048	Leptosphaeria maculans	19.88	4.00e-15	76.60
IUUC-Laf-053752	Loxodonta africana	91.22	0.00e+00	826.00
IUUC-Mcc-054892	Macaca mulatta	93.77	0.00e+00	910.00
IUUC-Meu-056673	Macropus eugenii	73.44	4.00e-160	557.00
IUUC-Mor-057143	Magnaporthe oryzae	21.50	1.00e-08	55.50
IUUC-Mtr-057976	Medicago truncatula	27.06	3.00e-32	133.00
IUUC-Mga-059543	Meleagris gallopavo	77.04	0.00e+00	668.00
IUUC-Mmr-061534	Microcebus murinus	92.41	0.00e+00	877.00
IUUC-Mdo-062140	Monodelphis domestica	67.98	2.00e-166	578.00
IUUC-Mmu-063673	Mus musculus	88.72	0.00e+00	830.00
IUUC-Mpu-066328	Mustela putorius furo	91.37	0.00e+00	845.00
IUUC-Mlu-067938	Myotis lucifugus	91.63	0.00e+00	891.00
IUUC-Nle-069426	Nomascus leucogenys	92.76	0.00e+00	822.00
IUUC-Opr-070796	Ochotona princeps	83.66	4.00e-121	428.00
IUUC-Ont-072248	Oreochromis niloticus	59.60	2.00e-156	545.00
IUUC-Oan-072916	Ornithorhynchus anatinus	78.56	0.00e+00	751.00
IUUC-Ocu-074459	Oryctolagus cuniculus	84.87	0.00e+00	650.00
IUUC-Oba-075765	Oryza barthii	26.86	2.00e-29	123.00
IUUC-Obr-076005	Oryza brachyantha	27.18	3.00e-31	129.00
IUUC-Ogl-077916	Oryza glaberrima	27.25	1.00e-32	134.00
IUUC-Ogu-078263	Oryza glumaepatula	27.40	7.00e-30	125.00
IUUC-Oin-080096	Oryza indica	27.58	2.00e-23	103.00
IUUC-Ome-081928	Oryza meridionalis	27.45	6.00e-31	128.00
IUUC-Oni-082424	Oryza nivara	27.40	8.00e-30	124.00
IUUC-Oru-085117	Oryza rufipogon	27.40	8.00e-30	124.00
IUUC-Ola-087429	Oryzias latipes	57.14	1.00e-145	509.00
IUUC-Oga-087981	Otolemur garnettii	92.22	0.00e+00	867.00
IUUC-Oar-089927	Ovis aries	89.82	0.00e+00	833.00
IUUC-Ptr-090878	Pan troglodytes	93.39	0.00e+00	904.00
IUUC-Pan-092698	Papio anubis	93.77	0.00e+00	910.00
IUUC-Psi-093451	Pelodiscus sinensis	77.64	0.00e+00	720.00
IUUC-Ppa-096015	Physcomitrella patens	24.85	6.00e-13	69.30
IUUC-Pfo-096096	Poecilia formosa	58.60	3.00e-153	535.00
IUUC-Pab-098676	Pongo abelii	92.22	0.00e+00	883.00
IUUC-Pca-100418	Procavia capensis	95.79	7.00e-129	453.00
IUUC-Ppe-101898	Prunus persica	24.32	4.00e-23	102.00
IUUC-Pva-103018	Pteropus vampyrus	89.28	0.00e+00	846.00
IUUC-Pgr-103423	Puccinia graminis	26.02	3.00e-10	60.80
IUUC-Pte-104330	Pyrenophora teres	21.18	1.00e-13	71.60
IUUC-Pyt-104518	Pyrenophora triticirepentis	21.23	1.00e-16	82.00
IUUC-Rno-105708	Rattus norvegicus	87.74	0.00e+00	817.00
IUUC-Sha-106971	Sarcophilus harrisii	81.08	0.00e+00	767.00
IUUC-Sit-110442	Setaria italica	27.77	4.00e-29	122.00
IUUC-Stu-112223	Solanum tuberosum	22.57	1.00e-15	77.80
IUUC-Ssc-116397	Sus scrofa	89.49	0.00e+00	828.00
IUUC-Tgu-117446	Taeniopygia guttata	70.60	0.00e+00	642.00
IUUC-Tru-118268	Takifugu rubripes	58.60	6.00e-144	504.00
IUUC-Tsy-119484	Tarsius syrichta	86.61	1.00e-51	197.00
IUUC-Tni-119735	Tetraodon nigroviridis	54.95	1.00e-122	433.00
IUUC-Tca-121660	Theobroma cacao	25.42	3.00e-28	120.00
IUUC-Tae-125383	Triticum aestivum	27.87	2.00e-28	120.00
IUUC-Tur-126458	Triticum urartu	27.41	4.00e-26	112.00
IUUC-Tbe-127740	Tupaia belangeri	85.80	0.00e+00	775.00
IUUC-Ttr-129273	Tursiops truncatus	88.62	0.00e+00	820.00
IUUC-Uma-129375	Ustilago maydis	26.85	3.00e-14	73.60
IUUC-Vvi-131177	Vitis vinifera	26.16	6.00e-27	115.00
IUUC-Xtr-132374	Xenopus tropicalis	68.43	2.00e-172	598.00
IUUC-Xma-133267	Xiphophorus maculatus	59.88	2.00e-155	541.00
IUUC-Yli-134571	Yarrowia lipolytica	23.81	9.00e-12	65.10

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence