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Tag Content
UUCD2 ID IUUC-Bta-012911
UUCD1 version UUC-BoT-01114
Ensembl Protein ID ENSBTAP00000011820.2
UniProt Accession E1BGQ9; E1BGQ9_BOVIN
Genbank Protein ID ENSBTAP00000011820
Protein Name Ubiquitinyl hydrolase 1
Genbank Nucleotide ID DAAA02055061
Gene Name USP49
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSBTAG00000008981.3 ENSBTAT00000011820.2 ENSBTAP00000011820.2
Status Unreviewed
Classification
Family E-Value Score Start End
DUB/USP 2.20e-98 329.7 247 651
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   DUB/USP
   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenp............................................... 42
           tGl+NlgNtCYmNS+LQ+Ls+++++re++l+ +++k+++  p                                               
   Q: 247  TGLRNLGNTCYMNSILQVLSHLRKFRECFLNLDPSKTEQLFPraangkaplsgrpasssatelsstrsdgaeacereglclnggtslsr 335
           7******************************7777777777777788888*************************************** PP
   S: 43   ..........kepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeqqDaqEflaflldqleeelkkeknkpkeeeeee 121
                     ++++ +l+++l++lf+ +w++k+  vsp ++l++++++ + f+gy+qqDaqEfl+ ll+++++el         e+e++
   Q: 336  sleliqnkepSSKHISLCHELHTLFRVMWSGKWALVSPFAMLHSVWSLIPAFRGYDQQDAQEFLCELLHKVQQEL---------ESEGT 415
           ****99999999999************************************************************.........66888 PP
   S: 122  dkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkke..........slqdcLesftkeeel 200
           +++ l   +++k +k+  ++++++F+gql sq++c +c+ +s++ epf+dlsl++p++ ++ ++           l+++L++ft++e l
   Q: 416  TRRILIPFSQRKLTKQVLKVVNTIFHGQLLSQVTCVSCNYKSNTIEPFWDLSLEFPERYHCIEKgfvplnqtecLLTEMLAKFTETEAL 504
           88999999***************************************************998879************************ PP
   S: 201  egenkyycekckkkqe...........aekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfctspeekqke..kk 276
           eg+  y c++c++k++           a+k+l++ +lP+vL lhLkRf++s + ++reki  +v f + L+++p+c+++  ++ +  + 
   Q: 505  EGRI-YACDQCNSKRRksnpkplvlseARKQLMIYRLPQVLRLHLKRFRWSGR-NHREKIGVHVVFDQVLTMEPYCCRDMLSSLDkeTF 591
           *965.*******9999999*******************************997.8889********************87665443399 PP
   S: 277  kYeLiavvvHsG.slssGHYvayvknekgk.WllfdDskVtevkeeevleetgstaYvlfYkr 337
            Y+L+avv+H+G +++sGHY+ay++n++g+ W++++Dsk ++++ eev++   ++aY+lfY++
   Q: 592  AYDLSAVVMHHGkGFGSGHYTAYCYNTEGGfWVHCNDSKLNVCSVEEVCK---TQAYILFYTQ 651
           9*************************9999********************...********98 PP
   
Organism Bos taurus
Protein Sequence
(Fasta)
MDRCKHVGRL RLAQDHSILN PQKWYCRECA TTESVWACLK CSHVACGRYI EDHALKHFEE 60
TRHPLAMEVR DLYVFCYLCK DYVLNDNPEG DLKLLRSSLL AVRGQTQDPP LRRGRTLRSM 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Bta-012911|DUB,USP|Bos taurus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGGATAGAT GCAAACATGT AGGGCGGTTG CGGCTCGCCC AGGACCACTC CATCCTGAAC 60
CCGCAGAAGT GGTACTGCCG GGAGTGCGCC ACCACCGAGT CGGTGTGGGC TTGTCTCAAG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Bta-012911|DUB,USP|Bos taurus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP
PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP
Pfam

PF00443--UCH
PF02148--zf-UBP
SMART

SM00290--ZnF_UBP
Gene Ontology

GO:0004197--F:cysteine-type endopeptidase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008270--F:zinc ion binding
GO:0035616--P:histone H2B conserved C-terminal lysine deubiquitination
GO:0000398--P:mRNA splicing, via spliceosome
GO:0006511--P:ubiquitin-dependent protein catabolic process
KEGG bta:517349
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002395 Ailuropoda melanoleuca 96.50 0.00e+00 863.00
IUUC-Apl-003658 Anas platyrhynchos 78.34 0.00e+00 1046.00
IUUC-Aca-005278 Anolis carolinensis 78.83 0.00e+00 1068.00
IUUC-Cja-019171 Callithrix jacchus 90.84 0.00e+00 1199.00
IUUC-Cfa-020408 Canis familiaris 94.87 0.00e+00 1204.00
IUUC-Cpo-022233 Cavia porcellus 84.03 0.00e+00 1060.00
IUUC-Csa-024272 Chlorocebus sabaeus 89.97 0.00e+00 950.00
IUUC-Cho-025051 Choloepus hoffmanni 90.60 0.00e+00 657.00
IUUC-Dno-029856 Dasypus novemcinctus 88.27 0.00e+00 1165.00
IUUC-Ete-032761 Echinops telfairi 74.28 0.00e+00 821.00
IUUC-Eca-033851 Equus caballus 84.10 0.00e+00 1023.00
IUUC-Fca-035919 Felis catus 95.52 0.00e+00 801.00
IUUC-Fal-037290 Ficedula albicollis 75.47 0.00e+00 925.00
IUUC-Gmo-039249 Gadus morhua 77.67 4.00e-146 511.00
IUUC-Gac-042595 Gasterosteus aculeatus 60.20 0.00e+00 753.00
IUUC-Ggo-044979 Gorilla gorilla 91.28 0.00e+00 1182.00
IUUC-Hsa-046743 Homo sapiens 91.13 0.00e+00 1177.00
IUUC-Itr-048251 Ictidomys tridecemlineatus 90.96 0.00e+00 1196.00
IUUC-Lch-050294 Latimeria chalumnae 75.75 0.00e+00 949.00
IUUC-Loc-051961 Lepisosteus oculatus 68.35 0.00e+00 809.00
IUUC-Laf-053819 Loxodonta africana 94.41 0.00e+00 852.00
IUUC-Mcc-055048 Macaca mulatta 91.13 0.00e+00 1179.00
IUUC-Meu-055971 Macropus eugenii 66.00 4.00e-142 498.00
IUUC-Mmr-061253 Microcebus murinus 86.67 3.00e-156 545.00
IUUC-Mdo-062073 Monodelphis domestica 80.95 0.00e+00 1081.00
IUUC-Mmu-064095 Mus musculus 88.34 0.00e+00 1155.00
IUUC-Mpu-066318 Mustela putorius furo 95.44 0.00e+00 875.00
IUUC-Mlu-067090 Myotis lucifugus 90.63 0.00e+00 1155.00
IUUC-Nle-069486 Nomascus leucogenys 91.72 0.00e+00 1188.00
IUUC-Opr-070563 Ochotona princeps 88.81 0.00e+00 1166.00
IUUC-Oan-073245 Ornithorhynchus anatinus 89.43 0.00e+00 627.00
IUUC-Ocu-074851 Oryctolagus cuniculus 89.57 0.00e+00 940.00
IUUC-Ola-086413 Oryzias latipes 57.93 0.00e+00 699.00
IUUC-Oga-088862 Otolemur garnettii 89.70 0.00e+00 1162.00
IUUC-Oar-089462 Ovis aries 94.52 0.00e+00 848.00
IUUC-Ptr-091525 Pan troglodytes 91.07 0.00e+00 1059.00
IUUC-Pan-092363 Papio anubis 91.40 0.00e+00 1134.00
IUUC-Psi-093353 Pelodiscus sinensis 79.69 0.00e+00 1057.00
IUUC-Pma-094155 Petromyzon marinus 59.18 1.00e-81 296.00
IUUC-Pfo-096413 Poecilia formosa 60.89 0.00e+00 773.00
IUUC-Pab-098592 Pongo abelii 90.14 0.00e+00 952.00
IUUC-Pca-100449 Procavia capensis 89.44 0.00e+00 1160.00
IUUC-Pva-102868 Pteropus vampyrus 92.39 0.00e+00 1180.00
IUUC-Rno-105190 Rattus norvegicus 87.32 0.00e+00 1149.00
IUUC-Sha-107337 Sarcophilus harrisii 81.29 0.00e+00 1065.00
IUUC-Sar-113561 Sorex araneus 95.21 5.00e-95 341.00
IUUC-Ssc-115735 Sus scrofa 96.78 0.00e+00 1202.00
IUUC-Tgu-117025 Taeniopygia guttata 71.32 0.00e+00 851.00
IUUC-Tru-117585 Takifugu rubripes 61.47 0.00e+00 758.00
IUUC-Tsy-118814 Tarsius syrichta 91.00 0.00e+00 1165.00
IUUC-Tni-120600 Tetraodon nigroviridis 60.12 0.00e+00 727.00
IUUC-Vpa-130263 Vicugna pacos 97.19 0.00e+00 790.00
IUUC-Xtr-132090 Xenopus tropicalis 69.79 0.00e+00 913.00
Created Date 25-Jun-2017

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