iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-053819

UUCD1 version

UUC-LoA-01087

Ensembl Protein ID

ENSLAFP00000014393.3

UniProt Accession

G3TIC6; G3TIC6_LOXAF

Protein Name

Uncharacterized protein

Gene Name

USP49

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000017166.3	ENSLAFT00000017164.3	ENSLAFP00000014393.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.90e-92	309.8	1	397

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 9    tCYmNSvLQcLsnipelrelllekkkeklneenp....................................................... 42
           tCYmNS+LQ+Ls+++++re++l+ +++k+++  p                                                       
   Q: 1    TCYMNSILQVLSHLQKFRECFLNLDPSKTEQLFPkatngkahlsskpasssatevsargdkaelcdreglclnggasisrsleliqnke 89
           9**********************777777777777777888899999999999999999999999999999999999999999999999 PP
   S: 43   .kepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdea 130
            ++++ +l+++l++lf+ +w++k+  vsp ++l++++++ + f+gy+qqDaqEfl+ ll+++++el         e+e+++++ l   +
   Q: 90   pSSKHISLCHELHTLFRVMWSGKWALVSPFAMLHSVWSLIPAFRGYDQQDAQEFLCELLHKVQQEL---------EAEGTTHRILIPFS 169
           889999************************************************************.........7788888999999* PP
   S: 131  eekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkke..........slqdcLesftkeeelegenkyyce 209
           ++k +k+  ++++++F+gql sq++c +c+ +s++ epf+dlsl++p++ ++ ++           l+++L++ft++e leg+  y c+
   Q: 170  QRKLTKQVLKVVNTIFHGQLLSQVTCIACNYKSNTIEPFWDLSLEFPERYHCIEKgfvplnqtecLLTEMLAKFTETEALEGRI-YACD 257
           **************************************************998879*************************965.**** PP
   S: 210  kckkkqe...........aekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfctspeekqke..kkkYeLiavvv 285
           +c++k++           a+k+l++ +lP+vL lhLkRf++s + ++reki  +v f + L+++p+c+++  ++ +  +  Y+L+avv+
   Q: 258  QCNSKRRksnpkplvlseARKQLMIYRLPQVLRLHLKRFRWSGR-NHREKIGVHVVFDQVLTMEPYCCRDMLSSLDkeTFAYDLSAVVM 345
           ***9999999*******************************997.8889********************876654433999******** PP
   S: 286  HsG.slssGHYvayvknekgk.WllfdDskVtevkeeevleetgstaYvlfYkrr 338
           H+G +++sGHY+ay++n++g+ W++++Dsk ++++ eev++   ++aY+lfY++r
   Q: 346  HHGkGFGSGHYTAYCYNTEGGfWVHCNDSKLNVCSVEEVCK---TQAYILFYTQR 397
           *****************9999********************...********985 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

TCYMNSILQV LSHLQKFREC FLNLDPSKTE QLFPKATNGK AHLSSKPASS SATEVSARGD 60
KAELCDREGL CLNGGASISR SLELIQNKEP SSKHISLCHE LHTLFRVMWS GKWALVSPFA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACCTGCTACA TGAACTCCAT CCTCCAGGTC CTCAGCCACC TCCAGAAGTT CCGAGAATGT 60
TTTTTGAACC TTGACCCTTC CAAAACGGAA CAACTGTTTC CCAAAGCGAC CAACGGGAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002395	Ailuropoda melanoleuca	94.85	0.00e+00	851.00
IUUC-Bta-012911	Bos taurus	94.17	0.00e+00	830.00
IUUC-Cja-019171	Callithrix jacchus	93.91	0.00e+00	843.00
IUUC-Cfa-020408	Canis familiaris	94.38	0.00e+00	840.00
IUUC-Cpo-022233	Cavia porcellus	89.02	0.00e+00	790.00
IUUC-Cho-025051	Choloepus hoffmanni	92.57	0.00e+00	672.00
IUUC-Dno-029856	Dasypus novemcinctus	95.79	0.00e+00	863.00
IUUC-Fca-035919	Felis catus	94.51	0.00e+00	799.00
IUUC-Gmo-039249	Gadus morhua	76.73	7.00e-145	507.00
IUUC-Gga-040383	Gallus gallus	84.42	0.00e+00	730.00
IUUC-Ggo-044979	Gorilla gorilla	94.61	0.00e+00	848.00
IUUC-Hsa-046743	Homo sapiens	94.38	0.00e+00	846.00
IUUC-Itr-048251	Ictidomys tridecemlineatus	94.63	0.00e+00	853.00
IUUC-Loc-051961	Lepisosteus oculatus	76.34	3.00e-178	618.00
IUUC-Mcc-055048	Macaca mulatta	94.61	0.00e+00	849.00
IUUC-Mga-059720	Meleagris gallopavo	84.15	0.00e+00	727.00
IUUC-Mmu-064095	Mus musculus	90.19	0.00e+00	812.00
IUUC-Mpu-066318	Mustela putorius furo	93.69	0.00e+00	844.00
IUUC-Mlu-067090	Myotis lucifugus	91.59	0.00e+00	823.00
IUUC-Nle-069486	Nomascus leucogenys	94.61	0.00e+00	849.00
IUUC-Opr-070563	Ochotona princeps	90.44	0.00e+00	812.00
IUUC-Oan-073245	Ornithorhynchus anatinus	88.86	3.00e-180	624.00
IUUC-Oga-088862	Otolemur garnettii	93.46	0.00e+00	825.00
IUUC-Oar-089462	Ovis aries	89.51	0.00e+00	791.00
IUUC-Ptr-091525	Pan troglodytes	94.81	0.00e+00	728.00
IUUC-Pan-092363	Papio anubis	95.52	0.00e+00	807.00
IUUC-Pma-094155	Petromyzon marinus	59.39	2.00e-82	298.00
IUUC-Pca-100449	Procavia capensis	95.34	0.00e+00	826.00
IUUC-Pva-102868	Pteropus vampyrus	95.09	0.00e+00	853.00
IUUC-Rno-105190	Rattus norvegicus	88.32	0.00e+00	800.00
IUUC-Sar-113561	Sorex araneus	95.21	2.00e-95	342.00
IUUC-Ssc-115735	Sus scrofa	94.39	0.00e+00	848.00
IUUC-Tsy-118814	Tarsius syrichta	93.93	0.00e+00	827.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence