iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ssc-115735

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Ubiquitinyl hydrolase 1

Genbank Nucleotide ID

CU914409

Gene Name

LOC100520499

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSSCG00000001629.2	ENSSSCT00000001812.2	ENSSSCP00000001766.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.10e-98	330.8	247	650

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenp............................................... 42
           tGl+NlgNtCYmNS+LQ+Ls+++++re++l+ +++k+++  p                                               
   Q: 247  TGLRNLGNTCYMNSILQVLSHLRKFRECFLNLDPSKTEQLFPraangkapltgrlasssatelsprsdgaetcereglclnggaslsrs 335
           7******************************7777777777777788888*************************************** PP
   S: 43   .........kepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeed 122
                    ++++ +l+++l++lf+ +w++k+  vsp ++l++++++ + f+gy+qqDaqEfl+ ll+++++el         e+e+++
   Q: 336  leliqnkepSSKHISLCHELHTLFRVMWSGKWALVSPFAMLHSVWSLIPAFRGYDQQDAQEFLCELLHKVQQEL---------ESEGTT 415
           ****9999999999************************************************************.........668888 PP
   S: 123  kselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkke..........slqdcLesftkeeele 201
           ++ l   +++k +k+  ++++++F+gql sq++c +c+ +s++ epf+dlsl++p++ ++ ++           l+++L++ft++e le
   Q: 416  RRILIPFSQRKLTKQVLKVVNTIFHGQLLSQVTCISCNYKSNTIEPFWDLSLEFPERYHCIEKgfvplnqtecLLTEMLAKFTETEALE 504
           8999999***************************************************998879************************* PP
   S: 202  genkyycekckkkqe...........aekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfctspeekqke..kkk 277
           g+  y c++c++k++           a+k+l++ +lP+vL lhLkRf++s + ++reki  +v f + L+++p+c+++  ++ +  +  
   Q: 505  GRI-YACDQCNSKRRksnpkplvlseARKQLMIYRLPQVLRLHLKRFRWSGR-NHREKIGVHVVFDQVLTMEPYCCRDMLSSLDkeTFA 591
           965.*******9999999*******************************997.8889********************876654433999 PP
   S: 278  YeLiavvvHsG.slssGHYvayvknekgk.WllfdDskVtevkeeevleetgstaYvlfYkr 337
           Y+L+avv+H+G +++sGHY+ay++n++g+ W++++Dsk ++++ eev++   ++aY+lfY++
   Q: 592  YDLSAVVMHHGkGFGSGHYTAYCYNTEGGfWVHCNDSKLNVCSVEEVCK---TQAYILFYTQ 650
           *************************9999********************...********98 PP

Organism

Sus scrofa

Protein Sequence
(Fasta)

MDRCKHVGRL RLAQDHSILN PQKWCCRECA TTESVWACLK CSHVACGRYI EDHALKHFEE 60
TGHPLAMEVR DLYVFCYLCK DYVLNDNPEG DLKLLRSSLL AVRGQTQDLP LRRGRTLRSM 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGATAGAT GCAAACATGT AGGGCGGTTG CGGCTCGCCC AGGACCATTC CATCCTGAAC 60
CCTCAGAAGT GGTGCTGCCG GGAGTGCGCC ACCACCGAGT CCGTGTGGGC TTGTCTCAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP

Pfam

PF00443--UCH
PF02148--zf-UBP

SMART

SM00290--ZnF_UBP

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0008270--F:zinc ion binding
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

ssc:100520499

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002395	Ailuropoda melanoleuca	96.02	0.00e+00	861.00
IUUC-Apl-003658	Anas platyrhynchos	78.05	0.00e+00	1046.00
IUUC-Aca-005278	Anolis carolinensis	78.19	0.00e+00	1070.00
IUUC-Bta-012911	Bos taurus	95.90	0.00e+00	1185.00
IUUC-Cja-019171	Callithrix jacchus	91.12	0.00e+00	1207.00
IUUC-Cfa-020408	Canis familiaris	95.89	0.00e+00	1205.00
IUUC-Cpo-022233	Cavia porcellus	85.32	0.00e+00	1075.00
IUUC-Csa-024272	Chlorocebus sabaeus	90.99	0.00e+00	967.00
IUUC-Cho-025051	Choloepus hoffmanni	90.86	0.00e+00	658.00
IUUC-Cin-025587	Ciona intestinalis	46.88	7.00e-108	385.00
IUUC-Dno-029856	Dasypus novemcinctus	89.97	0.00e+00	1179.00
IUUC-Ete-032761	Echinops telfairi	74.88	0.00e+00	839.00
IUUC-Eca-033851	Equus caballus	85.60	0.00e+00	1036.00
IUUC-Fca-035919	Felis catus	95.01	0.00e+00	798.00
IUUC-Fal-037290	Ficedula albicollis	75.33	0.00e+00	930.00
IUUC-Gmo-039249	Gadus morhua	77.67	3.00e-146	511.00
IUUC-Ggo-044979	Gorilla gorilla	92.29	0.00e+00	1198.00
IUUC-Hsa-046743	Homo sapiens	92.14	0.00e+00	1193.00
IUUC-Itr-048251	Ictidomys tridecemlineatus	92.41	0.00e+00	1220.00
IUUC-Lch-050294	Latimeria chalumnae	74.93	0.00e+00	939.00
IUUC-Loc-051961	Lepisosteus oculatus	67.72	0.00e+00	796.00
IUUC-Laf-053819	Loxodonta africana	94.39	0.00e+00	851.00
IUUC-Mcc-055048	Macaca mulatta	91.85	0.00e+00	1195.00
IUUC-Mmr-061253	Microcebus murinus	85.71	8.00e-156	543.00
IUUC-Mdo-062073	Monodelphis domestica	80.92	0.00e+00	1092.00
IUUC-Mmu-064095	Mus musculus	88.91	0.00e+00	1172.00
IUUC-Mpu-066318	Mustela putorius furo	94.76	0.00e+00	875.00
IUUC-Mlu-067090	Myotis lucifugus	92.52	0.00e+00	1187.00
IUUC-Nle-069486	Nomascus leucogenys	92.58	0.00e+00	1201.00
IUUC-Opr-070563	Ochotona princeps	88.65	0.00e+00	1169.00
IUUC-Oan-073245	Ornithorhynchus anatinus	89.71	0.00e+00	625.00
IUUC-Ocu-074851	Oryctolagus cuniculus	89.90	0.00e+00	943.00
IUUC-Ola-086413	Oryzias latipes	58.78	0.00e+00	718.00
IUUC-Oga-088862	Otolemur garnettii	90.26	0.00e+00	1182.00
IUUC-Oar-089462	Ovis aries	92.69	0.00e+00	830.00
IUUC-Ptr-091525	Pan troglodytes	92.33	0.00e+00	1076.00
IUUC-Pan-092363	Papio anubis	92.30	0.00e+00	1151.00
IUUC-Psi-093353	Pelodiscus sinensis	79.37	0.00e+00	1061.00
IUUC-Pma-094155	Petromyzon marinus	59.04	2.00e-82	298.00
IUUC-Pab-098592	Pongo abelii	91.33	0.00e+00	967.00
IUUC-Pca-100449	Procavia capensis	89.00	0.00e+00	1165.00
IUUC-Pva-102868	Pteropus vampyrus	93.84	0.00e+00	1191.00
IUUC-Rno-105190	Rattus norvegicus	87.74	0.00e+00	1160.00
IUUC-Sha-107337	Sarcophilus harrisii	81.26	0.00e+00	1075.00
IUUC-Sar-113561	Sorex araneus	94.61	1.00e-94	339.00
IUUC-Tgu-117025	Taeniopygia guttata	71.43	0.00e+00	863.00
IUUC-Tsy-118814	Tarsius syrichta	92.15	0.00e+00	1178.00
IUUC-Vpa-130263	Vicugna pacos	96.68	0.00e+00	790.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence