iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ptr-090767

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AACZ03110460

Gene Name

KLHL10

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000009182.5	ENSPTRT00000016898.5	ENSPTRP00000015642.5

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	2.80e-17	62.8	39	104
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	1.30e-11	43.5	138	169

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklde 67
           +Dv+++v+g ef+ah  +L+++Ss+F+alf++++++++ k+ ++i +++p+ ++ ++++ Yt ++++
   Q: 39   CDVVIKVNGFEFSAHMNILCSCSSYFRALFTSGWNNTE-KKVYNIPGISPDMMKLIIEYAYTRTVPI 104
           8**********************************998.***********************99986 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhFk 32
           l+Nc+gi+ f d y cp+L+++a +fil++F+
   Q: 138  LDNCIGICKFTDYYYCPELRQKAYMFILHNFE 169
           69*****************************5 PP

Organism

Pan troglodytes

Protein Sequence
(Fasta)

MEMESAAAST RFHQPHMERK MSAMACEIFN ELRLEGKLCD VVIKVNGFEF SAHMNILCSC 60
SSYFRALFTS GWNNTEKKVY NIPGISPDMM KLIIEYAYTR TVPITPDNVE KLLAAADQFN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGGATTCTGG AACTTGGGTT GCTTTATAGA CCCTATACAA AAGATGTAGT AGGGAAAAGG 60
AGCGACAACA GGCTAAAGGG GCCCCCCACA ACCCTCCCCG ACACCCTAGG AAAGCAGCCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0000902--P:cell morphogenesis
GO:0009566--P:fertilization
GO:0048873--P:homeostasis of number of cells within a tissue
GO:0048808--P:male genitalia morphogenesis
GO:0008584--P:male gonad development
GO:0016567--P:protein ubiquitination
GO:0007286--P:spermatid development

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001576	Ailuropoda melanoleuca	98.52	0.00e+00	1259.00
IUUC-Apl-003525	Anas platyrhynchos	81.99	0.00e+00	1047.00
IUUC-Aca-005295	Anolis carolinensis	88.12	0.00e+00	953.00
IUUC-Ang-009879	Aspergillus niger	27.56	3.00e-09	55.80
IUUC-Ate-010500	Aspergillus terreus	25.56	3.00e-19	89.70
IUUC-Ame-010953	Astyanax mexicanus	48.08	1.00e-163	569.00
IUUC-Bta-013447	Bos taurus	98.52	0.00e+00	1259.00
IUUC-Cja-019472	Callithrix jacchus	98.42	0.00e+00	786.00
IUUC-Cfa-020332	Canis familiaris	98.36	0.00e+00	1256.00
IUUC-Cpo-021949	Cavia porcellus	97.20	0.00e+00	1245.00
IUUC-Csa-023573	Chlorocebus sabaeus	99.34	0.00e+00	1267.00
IUUC-Cho-024451	Choloepus hoffmanni	97.42	0.00e+00	1089.00
IUUC-Cin-025680	Ciona intestinalis	51.40	3.00e-173	601.00
IUUC-Csv-026085	Ciona savignyi	50.17	2.00e-172	598.00
IUUC-Dre-028799	Danio rerio	57.66	0.00e+00	690.00
IUUC-Dno-029608	Dasypus novemcinctus	98.52	0.00e+00	1259.00
IUUC-Dor-030200	Dipodomys ordii	99.08	0.00e+00	1130.00
IUUC-Dme-031964	Drosophila melanogaster	45.63	2.00e-153	536.00
IUUC-Ete-032475	Echinops telfairi	95.07	0.00e+00	1209.00
IUUC-Eca-034237	Equus caballus	98.68	0.00e+00	1261.00
IUUC-Eeu-035104	Erinaceus europaeus	88.36	8.00e-167	579.00
IUUC-Fca-036271	Felis catus	98.36	0.00e+00	1259.00
IUUC-Fal-037352	Ficedula albicollis	68.41	0.00e+00	849.00
IUUC-Ggr-040046	Gaeumannomyces graminis	29.73	1.00e-06	48.10
IUUC-Gga-040205	Gallus gallus	79.97	0.00e+00	1012.00
IUUC-Gac-041982	Gasterosteus aculeatus	54.03	0.00e+00	638.00
IUUC-Ggo-045241	Gorilla gorilla	99.34	0.00e+00	1268.00
IUUC-Hsa-047022	Homo sapiens	99.67	0.00e+00	1272.00
IUUC-Itr-048079	Ictidomys tridecemlineatus	98.52	0.00e+00	1259.00
IUUC-Lch-050637	Latimeria chalumnae	86.80	0.00e+00	1131.00
IUUC-Loc-052412	Lepisosteus oculatus	74.88	0.00e+00	958.00
IUUC-Laf-054118	Loxodonta africana	98.36	0.00e+00	1258.00
IUUC-Mcc-055476	Macaca mulatta	91.28	0.00e+00	1139.00
IUUC-Meu-056158	Macropus eugenii	98.52	0.00e+00	1259.00
IUUC-Mpo-057379	Magnaporthe poae	32.88	9.00e-07	47.00
IUUC-Mga-059634	Meleagris gallopavo	80.88	0.00e+00	1001.00
IUUC-Mmr-061217	Microcebus murinus	89.14	0.00e+00	1110.00
IUUC-Mdo-062138	Monodelphis domestica	98.52	0.00e+00	1257.00
IUUC-Mmu-063769	Mus musculus	98.52	0.00e+00	1259.00
IUUC-Mpu-066045	Mustela putorius furo	98.68	0.00e+00	1261.00
IUUC-Mlu-067348	Myotis lucifugus	98.03	0.00e+00	1253.00
IUUC-Nfi-068435	Neosartorya fischeri	30.65	4.00e-07	47.80
IUUC-Nle-069331	Nomascus leucogenys	99.01	0.00e+00	1263.00
IUUC-Opr-071203	Ochotona princeps	95.72	0.00e+00	1214.00
IUUC-Ont-071882	Oreochromis niloticus	49.15	2.00e-157	549.00
IUUC-Ocu-073757	Oryctolagus cuniculus	98.35	0.00e+00	1253.00
IUUC-Ola-086791	Oryzias latipes	48.90	3.00e-151	528.00
IUUC-Oga-088676	Otolemur garnettii	98.36	0.00e+00	1256.00
IUUC-Oar-089804	Ovis aries	98.36	0.00e+00	1255.00
IUUC-Pan-092856	Papio anubis	99.34	0.00e+00	1267.00
IUUC-Psi-094041	Pelodiscus sinensis	92.26	0.00e+00	1195.00
IUUC-Pfo-096673	Poecilia formosa	57.99	0.00e+00	662.00
IUUC-Pab-097694	Pongo abelii	99.01	0.00e+00	1265.00
IUUC-Pca-100693	Procavia capensis	91.34	0.00e+00	987.00
IUUC-Pva-102153	Pteropus vampyrus	98.75	0.00e+00	837.00
IUUC-Rno-105012	Rattus norvegicus	98.52	0.00e+00	1259.00
IUUC-Sha-106593	Sarcophilus harrisii	98.52	0.00e+00	1259.00
IUUC-Ssl-108429	Sclerotinia sclerotiorum	24.46	4.00e-07	48.50
IUUC-Sar-113188	Sorex araneus	97.61	0.00e+00	1185.00
IUUC-Tgu-116852	Taeniopygia guttata	70.60	0.00e+00	841.00
IUUC-Tru-118098	Takifugu rubripes	48.82	2.00e-160	558.00
IUUC-Tsy-119581	Tarsius syrichta	84.70	0.00e+00	1048.00
IUUC-Tni-120002	Tetraodon nigroviridis	52.05	2.00e-163	568.00
IUUC-Tbe-127778	Tupaia belangeri	91.28	0.00e+00	1140.00
IUUC-Ttr-128966	Tursiops truncatus	92.27	0.00e+00	1157.00
IUUC-Vpa-130421	Vicugna pacos	98.68	0.00e+00	790.00
IUUC-Xtr-131853	Xenopus tropicalis	59.13	0.00e+00	684.00
IUUC-Xma-133112	Xiphophorus maculatus	58.35	0.00e+00	665.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence