iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aml-001540

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ACTA01146175

Gene Name

RBCK1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMEG00000014013.1	ENSAMET00000015393.1	ENSAMEP00000014783.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/ZnF/NZF	3.00e-11	42.7	196	221
ULD/UDP/UBQ/UBQ_Other	1.60e-06	28.0	60	120

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/ZnF/NZF

   S: 4    qWaCsaCTflNePeavkCemCsrpRg 29
           +W+C+ CTf+N+P +++CemC+r R+
   Q: 196  GWQCPGCTFINKPTRPGCEMCCRARP 221
           8************************8 PP

ULD/UDP/UBQ/UBQ_Other

   S: 4    tvksldgseltlk..vnpsdtVaeLKekiekklgippeqqrLiykGkiL.eddktLadyglk 62
            v++++  + t++  v p++tVa LK++++   g+pp  q++++ G+ L +d  tL ++g++
   Q: 60   SVEDAQMHTVTIWltVRPDMTVASLKDMVFLDYGFPPVLQQWVI-GQRLaRDQETLHSHGVR 120
           5666665577777889****************************.55555*********996 PP

Organism

Ailuropoda melanoleuca

Protein Sequence
(Fasta)

MDEKTKKAEE MALRLSRAVA GGDEQVAVQC AIWLAEQRVP LSVQLKPEVS PTQDIRLWVS 60
VEDAQMHTVT IWLTVRPDMT VASLKDMVFL DYGFPPVLQQ WVIGQRLARD QETLHSHGVR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGACGAGA AGACCAAGAA AGGTGGGCAC CCCCTGGAGG CGGCTGGGAA ACTTTCATTG 60
GGAGGTGGGC CCCAGCAGCA CCCGGCCTCG TCTTCCCGGA AGGGCCCGGG AGAGGGAGCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom
IPR027370--Znf-RING_LisH
IPR001876--Znf_RanBP2
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50053--UBIQUITIN_2
PS01358--ZF_RANBP2_1
PS50199--ZF_RANBP2_2
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13445--zf-RING_UBOX

SMART

SM00184--RING
SM00547--ZnF_RBZ

Gene Ontology

GO:0071797--C:LUBAC complex
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0060546--P:negative regulation of necroptotic process
GO:0032088--P:negative regulation of NF-kappaB transcription factor activity
GO:2001238--P:positive regulation of extrinsic apoptotic signaling pathway
GO:0042346--P:positive regulation of NF-kappaB import into nucleus
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0097039--P:protein linear polyubiquitination
GO:0050852--P:T cell receptor signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003627	Anas platyrhynchos	56.76	6.00e-17	78.20
IUUC-Aca-004507	Anolis carolinensis	63.44	4.00e-151	527.00
IUUC-Ame-011008	Astyanax mexicanus	51.97	6.00e-141	494.00
IUUC-Bta-013247	Bos taurus	90.98	0.00e+00	874.00
IUUC-Bci-013637	Botrytis cinerea	24.88	6.00e-13	69.70
IUUC-Cja-018880	Callithrix jacchus	90.98	0.00e+00	874.00
IUUC-Cfa-020477	Canis familiaris	94.51	0.00e+00	906.00
IUUC-Cpo-021558	Cavia porcellus	87.84	0.00e+00	832.00
IUUC-Csa-024129	Chlorocebus sabaeus	91.57	0.00e+00	847.00
IUUC-Cin-025630	Ciona intestinalis	38.84	5.00e-82	298.00
IUUC-Csv-026069	Ciona savignyi	50.80	5.00e-72	263.00
IUUC-Dre-027591	Danio rerio	52.15	1.00e-139	489.00
IUUC-Dno-029015	Dasypus novemcinctus	89.61	0.00e+00	843.00
IUUC-Dor-030313	Dipodomys ordii	80.88	0.00e+00	733.00
IUUC-Ete-032908	Echinops telfairi	78.40	0.00e+00	729.00
IUUC-Eca-034295	Equus caballus	77.14	0.00e+00	719.00
IUUC-Eeu-034454	Erinaceus europaeus	81.02	2.00e-112	399.00
IUUC-Fca-036380	Felis catus	95.69	0.00e+00	914.00
IUUC-Fal-037440	Ficedula albicollis	55.74	9.00e-16	74.30
IUUC-Gmo-038561	Gadus morhua	53.41	6.00e-118	417.00
IUUC-Gac-041319	Gasterosteus aculeatus	52.05	1.00e-138	486.00
IUUC-Ggo-044456	Gorilla gorilla	61.92	5.00e-146	510.00
IUUC-Hsa-045738	Homo sapiens	92.55	0.00e+00	848.00
IUUC-Itr-049042	Ictidomys tridecemlineatus	89.41	0.00e+00	833.00
IUUC-Lch-050269	Latimeria chalumnae	44.09	2.00e-113	403.00
IUUC-Loc-052776	Lepisosteus oculatus	49.91	8.00e-138	484.00
IUUC-Laf-054269	Loxodonta africana	88.82	0.00e+00	855.00
IUUC-Mcc-055669	Macaca mulatta	92.16	0.00e+00	854.00
IUUC-Mga-059615	Meleagris gallopavo	56.25	3.00e-17	79.00
IUUC-Mmr-061562	Microcebus murinus	90.29	0.00e+00	757.00
IUUC-Mdo-062263	Monodelphis domestica	77.95	0.00e+00	757.00
IUUC-Mmu-064325	Mus musculus	88.63	0.00e+00	818.00
IUUC-Mpu-066385	Mustela putorius furo	94.90	0.00e+00	909.00
IUUC-Mlu-067000	Myotis lucifugus	89.41	0.00e+00	839.00
IUUC-Nle-069812	Nomascus leucogenys	91.96	0.00e+00	849.00
IUUC-Opr-070575	Ochotona princeps	94.61	3.00e-107	382.00
IUUC-Ont-071314	Oreochromis niloticus	49.91	2.00e-134	473.00
IUUC-Ocu-074358	Oryctolagus cuniculus	79.85	0.00e+00	761.00
IUUC-Ola-086403	Oryzias latipes	51.98	1.00e-138	486.00
IUUC-Oga-087986	Otolemur garnettii	90.00	0.00e+00	833.00
IUUC-Oar-089600	Ovis aries	89.61	0.00e+00	878.00
IUUC-Ptr-091224	Pan troglodytes	92.35	0.00e+00	847.00
IUUC-Pan-092739	Papio anubis	92.35	0.00e+00	857.00
IUUC-Pma-094407	Petromyzon marinus	47.66	3.00e-126	445.00
IUUC-Pfo-097161	Poecilia formosa	51.47	8.00e-132	463.00
IUUC-Pab-098627	Pongo abelii	92.35	0.00e+00	841.00
IUUC-Pca-100641	Procavia capensis	89.94	0.00e+00	801.00
IUUC-Pva-102670	Pteropus vampyrus	91.57	0.00e+00	880.00
IUUC-Pte-104234	Pyrenophora teres	25.41	1.00e-11	63.90
IUUC-Rno-105504	Rattus norvegicus	87.84	0.00e+00	808.00
IUUC-Sha-107342	Sarcophilus harrisii	77.52	0.00e+00	773.00
IUUC-Sar-113425	Sorex araneus	88.58	2.00e-113	402.00
IUUC-Ssc-115904	Sus scrofa	93.06	3.00e-90	323.00
IUUC-Tru-118096	Takifugu rubripes	51.94	1.00e-141	496.00
IUUC-Tni-119873	Tetraodon nigroviridis	49.32	3.00e-138	485.00
IUUC-Tbe-127578	Tupaia belangeri	89.36	0.00e+00	689.00
IUUC-Ttr-129107	Tursiops truncatus	92.16	0.00e+00	848.00
IUUC-Vpa-130353	Vicugna pacos	89.47	1.00e-114	405.00
IUUC-Xtr-132168	Xenopus tropicalis	42.69	6.00e-94	337.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence