iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXETG00000003495.3	ENSXETT00000007563.3	ENSXETP00000007563.3
ENSXETG00000003495.3	ENSXETT00000062620.1	ENSXETP00000058398.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	2.30e-18	66.5	37	102
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	7.80e-07	28.4	136	167

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklde 67
           +Dv++++g+++f +hk+vLaasS++F al+ ++++es  ++ v+i+++ p +f+ +l+F+Ytg++++
   Q: 37   CDVQIQIGDVKFGVHKLVLAASSPYFAALLAGGMKESL-TEVVQIQGLNPNSFQLILDFIYTGSVKI 102
           8************************************9.************************9986 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhFk 32
           + Nc+g ++fA++++c  L ++ +++i++hF+
   Q: 136  PANCIGFFQFAEHLSCQPLLEYTESYIHTHFT 167
           57*****************************7 PP

Organism

Xenopus tropicalis

Protein Sequence
(Fasta)

MELVTETKAS TCLRILDKHA QLILAQMNRM RHQLEFCDVQ IQIGDVKFGV HKLVLAASSP 60
YFAALLAGGM KESLTEVVQI QGLNPNSFQL ILDFIYTGSV KISTDNVEDL MTAADMLQLS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGTTGACCAG TTATGGAACT AGTGACTGAA ACCAAAGCCA GCACCTGCCT GCGTATACTG 60
GACAAACATG CCCAGCTCAT TCTTGCACAG ATGAATCGGA TGAGACACCA GCTTGAGTTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR011043--Gal_Oxase/kelch_b-propeller
IPR030104--IPP
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001672	Ailuropoda melanoleuca	71.30	0.00e+00	882.00
IUUC-Apl-003849	Anas platyrhynchos	71.78	0.00e+00	873.00
IUUC-Aca-004563	Anolis carolinensis	66.79	0.00e+00	769.00
IUUC-Bta-013512	Bos taurus	70.83	0.00e+00	878.00
IUUC-Cja-018771	Callithrix jacchus	70.60	0.00e+00	875.00
IUUC-Cfa-020097	Canis familiaris	70.26	0.00e+00	823.00
IUUC-Cpo-022161	Cavia porcellus	70.42	0.00e+00	876.00
IUUC-Csa-024249	Chlorocebus sabaeus	70.60	0.00e+00	875.00
IUUC-Dno-029046	Dasypus novemcinctus	70.95	0.00e+00	878.00
IUUC-Dor-030510	Dipodomys ordii	71.24	3.00e-168	584.00
IUUC-Dme-031884	Drosophila melanogaster	36.97	1.00e-108	387.00
IUUC-Ete-032968	Echinops telfairi	65.32	0.00e+00	783.00
IUUC-Eca-033203	Equus caballus	66.08	0.00e+00	800.00
IUUC-Fca-036451	Felis catus	71.13	0.00e+00	878.00
IUUC-Fal-036931	Ficedula albicollis	69.89	0.00e+00	862.00
IUUC-Gmo-039098	Gadus morhua	61.12	0.00e+00	734.00
IUUC-Gga-040552	Gallus gallus	72.18	0.00e+00	880.00
IUUC-Gac-041995	Gasterosteus aculeatus	65.50	0.00e+00	791.00
IUUC-Ggo-045305	Gorilla gorilla	65.06	0.00e+00	697.00
IUUC-Hsa-045757	Homo sapiens	70.77	0.00e+00	875.00
IUUC-Itr-048686	Ictidomys tridecemlineatus	70.77	0.00e+00	879.00
IUUC-Lch-049691	Latimeria chalumnae	57.48	6.00e-143	500.00
IUUC-Loc-052552	Lepisosteus oculatus	66.26	0.00e+00	809.00
IUUC-Laf-053779	Loxodonta africana	68.24	0.00e+00	838.00
IUUC-Mcc-054862	Macaca mulatta	69.76	0.00e+00	821.00
IUUC-Mga-060083	Meleagris gallopavo	72.36	0.00e+00	883.00
IUUC-Mvi-060512	Microbotryum violaceum	26.90	2.00e-06	48.50
IUUC-Mmr-061303	Microcebus murinus	64.86	0.00e+00	745.00
IUUC-Mdo-062064	Monodelphis domestica	71.48	0.00e+00	882.00
IUUC-Mmu-063410	Mus musculus	71.65	0.00e+00	880.00
IUUC-Mpu-066841	Mustela putorius furo	70.84	0.00e+00	824.00
IUUC-Mlu-067053	Myotis lucifugus	64.96	0.00e+00	781.00
IUUC-Nle-070066	Nomascus leucogenys	69.68	0.00e+00	762.00
IUUC-Ont-072640	Oreochromis niloticus	66.90	0.00e+00	812.00
IUUC-Oan-073110	Ornithorhynchus anatinus	70.16	0.00e+00	869.00
IUUC-Ocu-073916	Oryctolagus cuniculus	63.62	0.00e+00	773.00
IUUC-Ola-086579	Oryzias latipes	59.45	0.00e+00	720.00
IUUC-Oga-088373	Otolemur garnettii	70.60	0.00e+00	875.00
IUUC-Oar-089314	Ovis aries	70.47	0.00e+00	877.00
IUUC-Ptr-090515	Pan troglodytes	70.34	0.00e+00	819.00
IUUC-Pan-092367	Papio anubis	70.60	0.00e+00	875.00
IUUC-Psi-093109	Pelodiscus sinensis	70.25	0.00e+00	868.00
IUUC-Pma-094467	Petromyzon marinus	44.66	1.00e-124	440.00
IUUC-Pfo-096194	Poecilia formosa	66.32	0.00e+00	795.00
IUUC-Pab-098529	Pongo abelii	63.62	0.00e+00	709.00
IUUC-Pca-100654	Procavia capensis	77.32	8.00e-95	340.00
IUUC-Pva-102519	Pteropus vampyrus	64.68	3.00e-164	571.00
IUUC-Rno-105294	Rattus norvegicus	71.10	0.00e+00	869.00
IUUC-Sha-106587	Sarcophilus harrisii	70.18	0.00e+00	865.00
IUUC-Sar-113688	Sorex araneus	70.95	0.00e+00	874.00
IUUC-Tgu-117449	Taeniopygia guttata	70.42	0.00e+00	864.00
IUUC-Tru-118138	Takifugu rubripes	66.20	0.00e+00	799.00
IUUC-Tsy-118868	Tarsius syrichta	59.54	2.00e-134	472.00
IUUC-Tni-120684	Tetraodon nigroviridis	66.90	0.00e+00	830.00
IUUC-Ttr-128460	Tursiops truncatus	73.98	2.00e-162	565.00
IUUC-Vpa-130752	Vicugna pacos	70.42	0.00e+00	862.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence