iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mcc-055418

Ensembl Protein ID

ENSMMUP00000025467.3

UniProt Accession

H9ES82; F6T2I0; H9ES82_MACMU

Genbank Protein ID

AFE65241.1; AFI37733.1

Protein Name

Kelch-like protein 4 isoform 1

Genbank Nucleotide ID

JSUE03046177; JV047662

Gene Name

KLHL4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000019383.3	ENSMMUT00000027223.3	ENSMMUP00000025467.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	1.30e-16	61.8	182	249
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	5.50e-08	32.1	281	311

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkldene 69
           +Dv+l+ g  +++ah++vL+a S++F a+f+++  e k +++v +++v+p +++ l+++ Ytg l+++e
   Q: 182  CDVLLIAGHLRIPAHRLVLSAVSDYFAAMFTNDVLEAK-QEEVRMEGVDPNALNSLVQYAYTGILQLKE 249
           8************************************9.*************************99986 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhF 31
           ++Nclgi++f+d+ +c++L  +a++++  hF
   Q: 281  PSNCLGIRSFGDAQGCTELLNVAHKYTMEHF 311
           89************************98777 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MSVSGKKEFD VKQILRLRWR WFSHPFQGST NTGSCLQQEG YEHRGTPVQG RLKSHSRDRN 60
GLKKSNSPVH HNILAPVPGP APAHQRAVQN LQQHNLIVHF QANEDTPKAV PEKNLFQEAC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGTTTCTAC TGCAGCTACT GTACTTTGAT ACTGAAGAAG CAGGACTAGA TATCTGCAAG 60
TCCGAGCAGG AGGACTACAA GCCTGCAAAT CTAACAGCTG GAGAGTGTTG TGGTGGCTGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0005815--C:microtubule organizing center

KEGG

mcc:695270

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001422	Ailuropoda melanoleuca	90.27	0.00e+00	1280.00
IUUC-Apl-004156	Anas platyrhynchos	87.68	0.00e+00	1017.00
IUUC-Aca-004238	Anolis carolinensis	80.89	0.00e+00	1159.00
IUUC-Ame-011287	Astyanax mexicanus	70.02	0.00e+00	905.00
IUUC-Bta-013232	Bos taurus	89.56	0.00e+00	1156.00
IUUC-Cja-018916	Callithrix jacchus	97.00	0.00e+00	1384.00
IUUC-Cfa-020972	Canis familiaris	92.56	0.00e+00	1087.00
IUUC-Csa-023849	Chlorocebus sabaeus	99.58	0.00e+00	1455.00
IUUC-Dor-030708	Dipodomys ordii	84.84	0.00e+00	1213.00
IUUC-Ete-033156	Echinops telfairi	80.62	0.00e+00	810.00
IUUC-Eca-033542	Equus caballus	91.09	0.00e+00	1304.00
IUUC-Fal-036999	Ficedula albicollis	81.64	0.00e+00	1185.00
IUUC-Fox-038050	Fusarium oxysporum	30.86	4.00e-08	51.60
IUUC-Gmo-039532	Gadus morhua	81.61	0.00e+00	931.00
IUUC-Gga-040215	Gallus gallus	83.06	0.00e+00	1221.00
IUUC-Gac-041582	Gasterosteus aculeatus	81.34	0.00e+00	947.00
IUUC-Ggo-045074	Gorilla gorilla	98.61	0.00e+00	1446.00
IUUC-Hsa-046486	Homo sapiens	98.57	0.00e+00	1410.00
IUUC-Lch-050265	Latimeria chalumnae	82.45	0.00e+00	986.00
IUUC-Loc-052015	Lepisosteus oculatus	77.64	0.00e+00	1088.00
IUUC-Laf-053627	Loxodonta africana	90.53	0.00e+00	1325.00
IUUC-Meu-056859	Macropus eugenii	74.18	1.00e-147	516.00
IUUC-Mga-059582	Meleagris gallopavo	82.84	0.00e+00	1153.00
IUUC-Mmr-061648	Microcebus murinus	93.18	0.00e+00	1363.00
IUUC-Mdo-062785	Monodelphis domestica	85.79	0.00e+00	978.00
IUUC-Mmu-063807	Mus musculus	87.45	0.00e+00	1275.00
IUUC-Mpu-066279	Mustela putorius furo	92.21	0.00e+00	1082.00
IUUC-Mlu-067981	Myotis lucifugus	88.58	0.00e+00	1305.00
IUUC-Nle-070033	Nomascus leucogenys	98.43	0.00e+00	1404.00
IUUC-Ont-071932	Oreochromis niloticus	74.32	0.00e+00	1078.00
IUUC-Ocu-073854	Oryctolagus cuniculus	92.14	0.00e+00	1089.00
IUUC-Ola-087436	Oryzias latipes	73.07	0.00e+00	1044.00
IUUC-Oar-089952	Ovis aries	90.53	0.00e+00	1322.00
IUUC-Ptr-091649	Pan troglodytes	91.09	0.00e+00	1271.00
IUUC-Pan-091798	Papio anubis	99.86	0.00e+00	1461.00
IUUC-Psi-093728	Pelodiscus sinensis	81.39	0.00e+00	1199.00
IUUC-Pfo-096954	Poecilia formosa	73.94	0.00e+00	1063.00
IUUC-Pab-098461	Pongo abelii	98.05	0.00e+00	1429.00
IUUC-Pva-102458	Pteropus vampyrus	90.97	0.00e+00	1186.00
IUUC-Rno-105865	Rattus norvegicus	88.42	0.00e+00	1282.00
IUUC-Sha-107322	Sarcophilus harrisii	84.89	0.00e+00	975.00
IUUC-Ssc-116001	Sus scrofa	93.14	0.00e+00	1364.00
IUUC-Tgu-116994	Taeniopygia guttata	82.61	0.00e+00	1199.00
IUUC-Tru-117780	Takifugu rubripes	69.54	0.00e+00	989.00
IUUC-Tni-120794	Tetraodon nigroviridis	72.26	0.00e+00	1004.00
IUUC-Tbe-128118	Tupaia belangeri	75.82	0.00e+00	969.00
IUUC-Vpa-130811	Vicugna pacos	87.73	0.00e+00	1237.00
IUUC-Xtr-132358	Xenopus tropicalis	79.86	0.00e+00	1177.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence