iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cin-025583

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

EAAA01001036

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCING00000002354.3	ENSCINT00000004794.3	ENSCINP00000004794.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.40e-97	326.0	721	1517

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgy 87
           Gl+NlgNtC+mNS LQc+sn+++l++++le k+  +ln++np ++kg+++k + +l +elw++ +k v+p +l  +++k+a++f+g+
   Q: 721  GLSNLGNTCFMNSGLQCISNTRPLTKYFLEnKHLFELNRTNPLGMKGHIAKRYCDLTQELWSGASKTVAPLKLRWTISKYAPRFNGF 807
           9*****************************88899**************************************************** PP
   S: 88   eqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde.....aeekkkkknkslisdlFqgqlksqikclecdnvssreepf 169
           +q+D+qE+laflld+l+e+l++ ++kp+ e++++d   ++de     a+e++  +n+s+i+dlF+gq++s+++cl+c+  s+r++pf
   Q: 808  SQHDSQELLAFLLDGLHEDLNRVQTKPYVELKDSDG--RPDEevaqeAWENHLARNQSIIVDLFHGQIRSRVRCLHCNAFSTRFDPF 892
           *******************************99983..333334555**************************************** PP
   S: 170  ldlslpvpgkeetkke....................................................................... 185
           + lslp+p+++++ +                                                                        
   Q: 893  TFLSLPLPMDNSMYLDvivirldgeipvrfglrlnmddtfvevrkhlaekckismeavllsevlgatiksflqdnlkvrslsigniy 979
           ***********87666*********************************************************************** PP
   S: 186  ....................................................................................... 185
                                                                                                  
   Q: 980  ayeipppvkaivratpngesrtgsaenknascnlvnsavepkqdntdsksgntdstcsteqsfsrrlceagdmqtqcagyvvayhrk 1066
           *************************************************************************************** PP
   S: 186  ....................................................................................... 185
                                                                                                  
   Q: 1067 tfhtdvyflssqkhrpslfglplvvpcvpgrpkkdlysavwklvsrlvsplppqeatavnhaqdcddsmgsqypfllrcvdafgmsc 1153
           *************************************************************************************** PP
   S: 186  ...................................................................slqdcLesftkeeelegenk 205
                                                                              +l++cL++ft+eeel +++ 
   Q: 1154 gnkcpwfrfctgciidcsddpwqqtsghisidwdptalhlryqpsaerevkddasveeghrgaqqriDLNHCLRAFTTEEELGKDEL 1240
           *************************************************************************************** PP
   S: 206  yycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple.Ldlspfcts........................ 267
           y+c kck +q a+kkl++++lP++Li+hLkRf+f +   + +k +k v+fp++ +d s+f+t+                        
   Q: 1241 YHCGKCKTRQLAKKKLDIWRLPPTLIIHLKRFQFVNG--RWIKSHKVVDFPKTdFDPSSFMTKrdeenigkhsvnvytmflpntytm 1325
           ********************************99775..5569********************555555555555555555555555 PP
   S: 268  ..........peekqke...................................................................... 274
                     +     +                                                                      
   Q: 1326 lfihfiftdiE-----Tsevtassitdsdpvktsiitsksspdakpskpkphisfeadephvtpgpvengaspapeegkksgltark 1407
           55555555550.....05555555555555555555555666666666666666666666777777777777777777777888888 PP
   S: 275  ................................................kkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDs 312
                                                                L+a  +HsG l++GHY+ay+kn+ ++ W++++Ds
   Q: 1408 rkpsfreespplydlyavsatlvcnyscytmgvlshrtfhdtftyndrLPLCALVALKCHSGILGGGHYIAYAKNKVNNkWYCYNDS 1494
           8889999999999999999999999999999999999999988888777788999********************75555******* PP
   S: 313  kVtevkeeevleetgstaYvlfYkrr 338
           +++ev+ ++++    +taY lfY+r+
   Q: 1495 SCKEVSADNICV---ETAYTLFYERQ 1517
           ************...*********96 PP

Organism

Ciona intestinalis

Protein Sequence
(Fasta)

MGAKESRASI LSYDEASKRV TSIELQRLQE AYKRSCGYAG IMREAVFVRD VLGENVPTKL 60
SQRIFNVMSS NSRGMSFRDL LVTLVLLTRG RQEERLKLTY AVYSDERGSC VTSTSMSSMV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GACTTTATAA ACTGTAGGGC AAAATTTGTC ATTTTGATAA TGAATCTGAA TTTATCAACT 60
CAAGGATAAT CTCTCATTTA AGAATGAGAT AAAATATTCA AATCTTCAAT TTTCCATCTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0106--Calcium
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011992--EF-hand-dom_pair
IPR018247--EF_Hand_1_Ca_BS
IPR002048--EF_hand_dom
IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS51283--DUSP
PS00018--EF_HAND_1
PS50222--EF_HAND_2
PS00972--USP_1
PS50235--USP_3

Pfam

PF06337--DUSP
PF13202--EF-hand_5
PF00443--UCH

SMART

SM00695--DUSP
SM00054--EFh

Gene Ontology

GO:0005509--F:calcium ion binding
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001611	Ailuropoda melanoleuca	51.31	0.00e+00	1061.00
IUUC-Apl-003272	Anas platyrhynchos	46.44	0.00e+00	1315.00
IUUC-Aca-005057	Anolis carolinensis	49.20	0.00e+00	1202.00
IUUC-Ame-010781	Astyanax mexicanus	49.26	0.00e+00	1235.00
IUUC-Bta-013502	Bos taurus	48.91	0.00e+00	1128.00
IUUC-Cja-018754	Callithrix jacchus	50.87	0.00e+00	1259.00
IUUC-Cfa-020526	Canis familiaris	50.53	0.00e+00	1238.00
IUUC-Cpo-021568	Cavia porcellus	49.57	0.00e+00	1138.00
IUUC-Csa-023143	Chlorocebus sabaeus	50.45	0.00e+00	1245.00
IUUC-Cho-024603	Choloepus hoffmanni	64.39	2.00e-74	273.00
IUUC-Csv-026344	Ciona savignyi	68.84	0.00e+00	2178.00
IUUC-Dre-028121	Danio rerio	48.96	0.00e+00	1222.00
IUUC-Dno-029911	Dasypus novemcinctus	50.15	0.00e+00	1211.00
IUUC-Dme-032094	Drosophila melanogaster	44.16	2.00e-115	409.00
IUUC-Ete-032639	Echinops telfairi	56.64	0.00e+00	739.00
IUUC-Eca-034253	Equus caballus	50.74	0.00e+00	1227.00
IUUC-Eeu-035084	Erinaceus europaeus	63.70	2.00e-111	396.00
IUUC-Fca-035474	Felis catus	50.43	0.00e+00	982.00
IUUC-Fal-036985	Ficedula albicollis	50.34	0.00e+00	1235.00
IUUC-Gmo-039568	Gadus morhua	50.38	0.00e+00	1221.00
IUUC-Gga-040509	Gallus gallus	50.26	0.00e+00	1291.00
IUUC-Gac-041757	Gasterosteus aculeatus	50.00	0.00e+00	1256.00
IUUC-Ggo-044956	Gorilla gorilla	46.53	0.00e+00	858.00
IUUC-Hsa-046107	Homo sapiens	50.41	0.00e+00	1264.00
IUUC-Itr-048865	Ictidomys tridecemlineatus	51.84	3.00e-105	374.00
IUUC-Lch-050681	Latimeria chalumnae	46.99	0.00e+00	1071.00
IUUC-Loc-052474	Lepisosteus oculatus	47.00	0.00e+00	927.00
IUUC-Laf-054273	Loxodonta africana	50.30	0.00e+00	1256.00
IUUC-Mcc-054718	Macaca mulatta	50.60	0.00e+00	1262.00
IUUC-Meu-056558	Macropus eugenii	39.44	0.00e+00	688.00
IUUC-Mga-059892	Meleagris gallopavo	50.54	0.00e+00	1221.00
IUUC-Mmr-060866	Microcebus murinus	50.60	0.00e+00	1257.00
IUUC-Mdo-062607	Monodelphis domestica	50.71	0.00e+00	1268.00
IUUC-Mmu-063797	Mus musculus	50.71	0.00e+00	1268.00
IUUC-Mpu-066121	Mustela putorius furo	50.78	0.00e+00	1269.00
IUUC-Mlu-067581	Myotis lucifugus	50.42	0.00e+00	1243.00
IUUC-Nle-069916	Nomascus leucogenys	49.02	0.00e+00	1213.00
IUUC-Opr-071073	Ochotona princeps	37.30	1.00e-115	410.00
IUUC-Ont-071310	Oreochromis niloticus	49.67	0.00e+00	1236.00
IUUC-Oan-073356	Ornithorhynchus anatinus	50.15	0.00e+00	1235.00
IUUC-Ocu-074216	Oryctolagus cuniculus	50.98	0.00e+00	1265.00
IUUC-Ola-087434	Oryzias latipes	49.28	0.00e+00	1192.00
IUUC-Oga-089034	Otolemur garnettii	50.63	0.00e+00	1202.00
IUUC-Oar-090369	Ovis aries	50.62	0.00e+00	1227.00
IUUC-Ptr-090605	Pan troglodytes	50.41	0.00e+00	1266.00
IUUC-Pan-092381	Papio anubis	49.73	0.00e+00	1203.00
IUUC-Psi-093819	Pelodiscus sinensis	50.62	0.00e+00	1228.00
IUUC-Pma-094480	Petromyzon marinus	47.24	0.00e+00	1016.00
IUUC-Pfo-096561	Poecilia formosa	49.04	0.00e+00	1206.00
IUUC-Pab-097643	Pongo abelii	48.84	0.00e+00	1194.00
IUUC-Pca-100944	Procavia capensis	49.03	1.00e-137	483.00
IUUC-Pva-102732	Pteropus vampyrus	46.07	0.00e+00	1105.00
IUUC-Rno-105113	Rattus norvegicus	50.38	0.00e+00	1239.00
IUUC-Sja-107748	Schizosaccharomyces japonicus	32.20	5.00e-56	211.00
IUUC-Sar-113201	Sorex araneus	45.11	0.00e+00	649.00
IUUC-Tgu-117322	Taeniopygia guttata	50.93	0.00e+00	1296.00
IUUC-Tru-118705	Takifugu rubripes	53.74	2.00e-128	452.00
IUUC-Tsy-119433	Tarsius syrichta	50.27	9.00e-153	533.00
IUUC-Tni-120631	Tetraodon nigroviridis	49.16	0.00e+00	1194.00
IUUC-Tbe-127553	Tupaia belangeri	68.25	1.00e-113	403.00
IUUC-Ttr-128260	Tursiops truncatus	49.47	0.00e+00	1209.00
IUUC-Vpa-130479	Vicugna pacos	49.34	0.00e+00	1090.00
IUUC-Xtr-132686	Xenopus tropicalis	54.51	0.00e+00	852.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence