iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Apl-003996

Ensembl Protein ID

ENSAPLP00000001138.1

UniProt Accession

U3I1L8; U3I1L8_ANAPL

Genbank Protein ID

ENSAPLP00000001138

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADON01124690

Gene Name

TRIM59

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAPLG00000001715.1	ENSAPLT00000001709.1	ENSAPLP00000001138.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	6.10e-08	32.8	10	60

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefr..........CPlCr 46
           C+iC++ f+d p+vlpC H+f+++Cl+ +       s++f+          CP Cr
   Q: 10   CSICYSLFSD-PRVLPCSHTFCRNCLEGV----LDLSGNFSiwrplrillkCPNCR 60
           **********.**************8666....334444444444455555****8 PP

Organism

Anas platyrhynchos

Protein Sequence
(Fasta)

MHHFEEELTC SICYSLFSDP RVLPCSHTFC RNCLEGVLDL SGNFSIWRPL RILLKCPNCR 60
SVVEIPDSGT ESLPINFALK AIIEKYRQED HSDVATCSEH YRQPLNVYCL LDKKMVCGHC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCATCACT TTGAGGAAGA GTTAACGTGC TCCATCTGCT ACAGCCTGTT TTCAGATCCC 60
CGTGTTCTGC CTTGTTCCCA TACATTCTGT AGAAATTGTC TGGAGGGTGT CCTTGATCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR027370--Znf-RING_LisH
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00643--zf-B_box
PF13445--zf-RING_UBOX

SMART

SM00184--RING

Gene Ontology

GO:0005783--C:endoplasmic reticulum
GO:0016021--C:integral component of membrane
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:0043124--P:negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0046597--P:negative regulation of viral entry into host cell

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002249	Ailuropoda melanoleuca	58.02	1.00e-131	462.00
IUUC-Aca-005141	Anolis carolinensis	62.34	6.00e-144	503.00
IUUC-Ame-011353	Astyanax mexicanus	51.96	1.00e-97	349.00
IUUC-Bta-013440	Bos taurus	61.56	1.00e-128	451.00
IUUC-Cfa-021168	Canis familiaris	57.88	7.00e-135	473.00
IUUC-Cpo-021702	Cavia porcellus	62.66	2.00e-117	415.00
IUUC-Csa-024141	Chlorocebus sabaeus	58.52	3.00e-120	424.00
IUUC-Dre-028408	Danio rerio	44.95	1.00e-82	300.00
IUUC-Dno-029180	Dasypus novemcinctus	57.64	1.00e-130	459.00
IUUC-Eca-034357	Equus caballus	58.27	1.00e-129	456.00
IUUC-Fca-036287	Felis catus	58.94	2.00e-133	468.00
IUUC-Gga-040739	Gallus gallus	79.90	0.00e+00	673.00
IUUC-Ggo-045307	Gorilla gorilla	57.53	5.00e-128	450.00
IUUC-Hsa-045690	Homo sapiens	57.78	2.00e-128	452.00
IUUC-Itr-048230	Ictidomys tridecemlineatus	57.78	3.00e-132	464.00
IUUC-Laf-054522	Loxodonta africana	56.05	3.00e-130	457.00
IUUC-Mcc-055145	Macaca mulatta	58.77	3.00e-129	454.00
IUUC-Mmr-061197	Microcebus murinus	58.77	2.00e-134	472.00
IUUC-Mmu-064217	Mus musculus	55.56	2.00e-126	445.00
IUUC-Mpu-065691	Mustela putorius furo	57.64	2.00e-133	468.00
IUUC-Mlu-067742	Myotis lucifugus	57.28	1.00e-126	445.00
IUUC-Nle-069722	Nomascus leucogenys	58.62	2.00e-135	474.00
IUUC-Oan-073382	Ornithorhynchus anatinus	54.48	6.00e-125	440.00
IUUC-Oar-089206	Ovis aries	57.28	4.00e-133	467.00
IUUC-Pan-092189	Papio anubis	59.01	5.00e-130	457.00
IUUC-Psi-093523	Pelodiscus sinensis	71.11	3.00e-159	553.00
IUUC-Pma-094162	Petromyzon marinus	32.20	2.00e-47	182.00
IUUC-Pfo-096032	Poecilia formosa	46.91	2.00e-86	311.00
IUUC-Pva-103089	Pteropus vampyrus	57.78	4.00e-127	447.00
IUUC-Rno-105440	Rattus norvegicus	54.57	7.00e-128	449.00
IUUC-Ssc-115809	Sus scrofa	56.79	4.00e-124	437.00
IUUC-Tru-118402	Takifugu rubripes	46.82	4.00e-89	321.00
IUUC-Tni-119737	Tetraodon nigroviridis	44.48	2.00e-84	305.00
IUUC-Ttr-128921	Tursiops truncatus	57.78	6.00e-127	446.00
IUUC-Vpa-130397	Vicugna pacos	57.64	4.00e-134	470.00
IUUC-Xtr-132752	Xenopus tropicalis	46.56	1.00e-91	329.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence