iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mlu-067597

Ensembl Protein ID

ENSMLUP00000016089.2

UniProt Accession

G1PXC3; G1PXC3_MYOLU

Genbank Protein ID

ENSMLUP00000016089

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02024187

Gene Name

PACSIN3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000017640.2	ENSMLUT00000017644.2	ENSMLUP00000016089.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	8.50e-14	51.3	379	433

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
           +v++lydy +q+ deL++++G+ +l +  ee ++gW++g+   +g+ Gl P+n+ve 
   Q: 379  RVRALYDYAGQEADELSFRAGEELLKM-SEEDEQGWCQGQ-LQSGRIGLYPANYVEC 433
           689********************9999.999********7.99************85 PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

RDTMAPEEDT GGEALEGSFW EAGNYRRTVQ RVEDGHRLCG DLVSCFQERA RIEKAYAQQL 60
ADWARKWRGT VEKGPQYGTL EKAWHAFFTA AERLSALHLE VREKLHGQDS ERVRAWQRGA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGGGACACCA TGGCTCCAGA GGAAGACACT GGAGGGGAGG CCCTAGAGGG CAGTTTCTGG 60
GAGGTGAGCA GATGGGTTTG GGGGTGGCAC TGTAATGCCC ACCCCTCTGG GCTCAGCCAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0728--SH3 domain

Interpro

IPR027267--AH/BAR-dom
IPR031160--F_BAR
IPR001060--FCH_dom
IPR028523--PACSIN3
IPR001452--SH3_domain

PROSITE

PS51741--F_BAR
PS50002--SH3

Pfam

PF00611--FCH
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00055--FCH
SM00326--SH3

Gene Ontology

GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0005886--C:plasma membrane
GO:0019855--F:calcium channel inhibitor activity
GO:0008289--F:lipid binding
GO:0051926--P:negative regulation of calcium ion transport
GO:0045806--P:negative regulation of endocytosis
GO:0097320--P:plasma membrane tubulation
GO:0051044--P:positive regulation of membrane protein ectodomain proteolysis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001906	Ailuropoda melanoleuca	93.41	0.00e+00	638.00
IUUC-Apl-003211	Anas platyrhynchos	64.04	2.00e-176	611.00
IUUC-Aca-004256	Anolis carolinensis	63.74	2.00e-174	605.00
IUUC-Ame-011049	Astyanax mexicanus	59.95	8.00e-150	523.00
IUUC-Bta-013322	Bos taurus	90.57	0.00e+00	754.00
IUUC-Cja-018907	Callithrix jacchus	90.95	0.00e+00	777.00
IUUC-Cfa-021126	Canis familiaris	90.95	0.00e+00	772.00
IUUC-Cpo-021491	Cavia porcellus	89.33	0.00e+00	765.00
IUUC-Csa-023107	Chlorocebus sabaeus	92.11	0.00e+00	783.00
IUUC-Dre-027933	Danio rerio	59.73	5.00e-144	504.00
IUUC-Dno-029002	Dasypus novemcinctus	89.33	0.00e+00	729.00
IUUC-Eca-033824	Equus caballus	90.26	0.00e+00	771.00
IUUC-Eeu-035122	Erinaceus europaeus	81.94	5.00e-165	573.00
IUUC-Fca-036420	Felis catus	92.11	0.00e+00	791.00
IUUC-Fal-037277	Ficedula albicollis	64.62	9.00e-178	616.00
IUUC-Gga-040941	Gallus gallus	64.69	2.00e-178	618.00
IUUC-Gac-041374	Gasterosteus aculeatus	59.95	2.00e-134	472.00
IUUC-Ggo-045211	Gorilla gorilla	92.15	0.00e+00	787.00
IUUC-Hsa-046053	Homo sapiens	92.11	0.00e+00	783.00
IUUC-Itr-047939	Ictidomys tridecemlineatus	90.49	0.00e+00	772.00
IUUC-Loc-052808	Lepisosteus oculatus	61.14	1.00e-152	533.00
IUUC-Laf-054211	Loxodonta africana	89.33	0.00e+00	733.00
IUUC-Mcc-055044	Macaca mulatta	92.11	0.00e+00	783.00
IUUC-Mga-059216	Meleagris gallopavo	64.77	2.00e-178	618.00
IUUC-Mmr-061172	Microcebus murinus	91.42	0.00e+00	781.00
IUUC-Mdo-062600	Monodelphis domestica	84.45	0.00e+00	744.00
IUUC-Mmu-063218	Mus musculus	88.86	0.00e+00	759.00
IUUC-Mpu-066819	Mustela putorius furo	92.84	0.00e+00	639.00
IUUC-Nle-069195	Nomascus leucogenys	91.88	0.00e+00	781.00
IUUC-Opr-071050	Ochotona princeps	90.49	0.00e+00	753.00
IUUC-Ont-071612	Oreochromis niloticus	55.31	6.00e-138	484.00
IUUC-Oan-073256	Ornithorhynchus anatinus	84.45	0.00e+00	717.00
IUUC-Ocu-074653	Oryctolagus cuniculus	89.79	0.00e+00	736.00
IUUC-Oga-089040	Otolemur garnettii	89.10	0.00e+00	769.00
IUUC-Oar-089918	Ovis aries	90.41	0.00e+00	753.00
IUUC-Ptr-091307	Pan troglodytes	92.11	0.00e+00	783.00
IUUC-Pan-092512	Papio anubis	92.11	0.00e+00	783.00
IUUC-Pfo-096881	Poecilia formosa	58.67	5.00e-149	520.00
IUUC-Pab-098620	Pongo abelii	92.11	0.00e+00	783.00
IUUC-Pva-102464	Pteropus vampyrus	89.56	0.00e+00	756.00
IUUC-Rno-106091	Rattus norvegicus	88.40	0.00e+00	756.00
IUUC-Sha-107474	Sarcophilus harrisii	85.15	0.00e+00	749.00
IUUC-Ssc-116128	Sus scrofa	90.72	0.00e+00	778.00
IUUC-Tgu-117511	Taeniopygia guttata	60.84	3.00e-172	597.00
IUUC-Tru-118005	Takifugu rubripes	59.59	1.00e-137	483.00
IUUC-Tni-119851	Tetraodon nigroviridis	61.03	8.00e-137	479.00
IUUC-Ttr-129313	Tursiops truncatus	91.42	0.00e+00	790.00
IUUC-Vpa-130760	Vicugna pacos	95.08	1.00e-99	356.00
IUUC-Xtr-132697	Xenopus tropicalis	55.71	5.00e-137	480.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence