iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tur-126237

Ensembl Protein ID

TRIUR3_15113-P1

UniProt Accession

T1MBW2; T1MBW2_TRIUA

Protein Name

Presenilin

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
TRIUR3_15113	TRIUR3_15113-T1	TRIUR3_15113-P1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/CUE	33.87	5.00e-30	128.00	IUUC-Cel-018553
UBD/Alpha-Helix/CUE	33.44	5.00e-23	106.00	IUUC-Dre-028689

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Triticum urartu

Functional Description
(View)

Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors.

Protein Sequence
(Fasta)

MVAPDDESAL KWAKEDYVCE QQQQQQEFSL AKSNSLKLVG ALLDAAVFVA LVAVVTFILV 60
ALYYYRCTGF LKNYMRFSAF FVLLSMGGAI AVALLRRLDA PLDAPTALLL LFNASAVGVL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGTGGCCC CTGACGACGA GTCCGCCCTC AAATGGGCGA AGGAAGACTA TGTCTGCGAG 60
CAGGTGCGCC GCCAGCATCG GGCGTACCTG GANNNNNNNN NNNNNNNNNN NNNNNNNNNN 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0256--Endoplasmic reticulum
KW-0333--Golgi apparatus
KW-0378--Hydrolase
KW-0472--Membrane
KW-0914--Notch signaling pathway
KW-0645--Protease
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR001108--Peptidase_A22A
IPR006639--Preselin/SPP

Pfam

PF01080--Presenilin

PRINTS

PR01072--PRESENILIN

SMART

SM00730--PSN

Gene Ontology

GO:0005789--C:endoplasmic reticulum membrane
GO:0000139--C:Golgi membrane
GO:0005798--C:Golgi-associated vesicle
GO:0016021--C:integral component of membrane
GO:0004190--F:aspartic-type endopeptidase activity
GO:0007219--P:Notch signaling pathway
GO:0016485--P:protein processing

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000686	Aegilops tauschii	97.70	2.00e-158	551.00
IUUC-Aml-001648	Ailuropoda melanoleuca	34.18	8.00e-32	130.00
IUUC-Atr-003039	Amborella trichopoda	54.81	2.00e-98	351.00
IUUC-Apl-003727	Anas platyrhynchos	34.27	2.00e-30	125.00
IUUC-Aca-004582	Anolis carolinensis	33.52	2.00e-31	129.00
IUUC-Aly-005455	Arabidopsis lyrata	61.05	3.00e-47	181.00
IUUC-Ath-006730	Arabidopsis thaliana	61.05	1.00e-48	186.00
IUUC-Ame-011500	Astyanax mexicanus	32.61	7.00e-17	80.90
IUUC-Bta-013026	Bos taurus	32.96	3.00e-30	125.00
IUUC-Bdi-014196	Brachypodium distachyon	83.65	4.00e-147	513.00
IUUC-Bol-015841	Brassica oleracea	60.23	6.00e-43	167.00
IUUC-Bra-017580	Brassica rapa	90.91	5.00e-42	164.00
IUUC-Cel-018553	Caenorhabditis elegans	31.84	1.00e-40	160.00
IUUC-Cja-019994	Callithrix jacchus	31.36	6.00e-28	117.00
IUUC-Cfa-020074	Canis familiaris	33.80	6.00e-31	127.00
IUUC-Cpo-022237	Cavia porcellus	34.26	3.00e-31	128.00
IUUC-Cre-022747	Chlamydomonas reinhardtii	43.35	1.00e-32	133.00
IUUC-Csa-023537	Chlorocebus sabaeus	32.49	2.00e-28	119.00
IUUC-Cho-024735	Choloepus hoffmanni	33.33	7.00e-27	114.00
IUUC-Cin-025780	Ciona intestinalis	32.99	4.00e-38	150.00
IUUC-Csv-025967	Ciona savignyi	37.34	3.00e-23	101.00
IUUC-Dre-028689	Danio rerio	31.59	2.00e-27	115.00
IUUC-Dno-029758	Dasypus novemcinctus	33.24	2.00e-30	125.00
IUUC-Dor-030609	Dipodomys ordii	54.32	8.00e-19	87.40
IUUC-Dme-031929	Drosophila melanogaster	39.76	2.00e-26	112.00
IUUC-Ete-032487	Echinops telfairi	60.49	1.00e-12	66.60
IUUC-Eca-033391	Equus caballus	28.40	2.00e-19	89.00
IUUC-Eeu-035134	Erinaceus europaeus	34.67	1.00e-30	125.00
IUUC-Fca-036243	Felis catus	34.09	2.00e-31	129.00
IUUC-Fal-036600	Ficedula albicollis	33.06	2.00e-31	129.00
IUUC-Gmo-039665	Gadus morhua	33.54	3.00e-19	89.00
IUUC-Gga-040993	Gallus gallus	33.24	6.00e-32	130.00
IUUC-Gac-042511	Gasterosteus aculeatus	34.15	2.00e-21	95.90
IUUC-Gma-043822	Glycine max	88.24	1.00e-40	159.00
IUUC-Ggo-045338	Gorilla gorilla	34.29	9.00e-25	107.00
IUUC-Hsa-046822	Homo sapiens	32.49	2.00e-28	119.00
IUUC-Hvu-047141	Hordeum vulgare	95.41	4.00e-164	570.00
IUUC-Itr-048420	Ictidomys tridecemlineatus	33.52	1.00e-33	135.00
IUUC-Lch-049638	Latimeria chalumnae	34.15	7.00e-23	100.00
IUUC-Lpe-051132	Leersia perrieri	73.67	2.00e-126	444.00
IUUC-Loc-052427	Lepisosteus oculatus	31.22	5.00e-33	134.00
IUUC-Laf-053979	Loxodonta africana	36.86	3.00e-28	118.00
IUUC-Mcc-055682	Macaca mulatta	32.49	2.00e-28	119.00
IUUC-Meu-056004	Macropus eugenii	33.33	2.00e-18	86.30
IUUC-Mtr-058392	Medicago truncatula	53.85	9.00e-88	316.00
IUUC-Mga-059466	Meleagris gallopavo	33.52	3.00e-32	131.00
IUUC-Mmr-060890	Microcebus murinus	34.58	2.00e-25	109.00
IUUC-Mdo-062122	Monodelphis domestica	32.76	1.00e-26	113.00
IUUC-Mmu-063176	Mus musculus	36.23	2.00e-19	89.40
IUUC-Mac-064858	Musa acuminata	93.18	1.00e-43	169.00
IUUC-Mpu-065927	Mustela putorius furo	32.48	3.00e-28	118.00
IUUC-Mlu-067079	Myotis lucifugus	33.98	9.00e-33	133.00
IUUC-Nle-070180	Nomascus leucogenys	32.49	2.00e-28	119.00
IUUC-Opr-070344	Ochotona princeps	34.12	2.00e-23	102.00
IUUC-Ont-071846	Oreochromis niloticus	31.25	8.00e-28	117.00
IUUC-Oan-072783	Ornithorhynchus anatinus	35.60	7.00e-31	126.00
IUUC-Ocu-074527	Oryctolagus cuniculus	33.90	4.00e-31	128.00
IUUC-Oba-075256	Oryza barthii	74.86	4.00e-115	406.00
IUUC-Obr-076302	Oryza brachyantha	76.13	4.00e-130	457.00
IUUC-Ogl-077097	Oryza glaberrima	75.55	2.00e-122	431.00
IUUC-Ogu-078570	Oryza glumaepatula	75.27	7.00e-122	429.00
IUUC-Oin-079244	Oryza indica	75.27	8.00e-122	429.00
IUUC-Olo-080484	Oryza longistaminata	77.05	5.00e-85	306.00
IUUC-Ome-081814	Oryza meridionalis	77.81	2.00e-123	434.00
IUUC-Oni-082057	Oryza nivara	75.27	5.00e-122	430.00
IUUC-Opu-084176	Oryza punctata	78.36	1.00e-125	442.00
IUUC-Oru-084618	Oryza rufipogon	75.27	3.00e-122	430.00
IUUC-Osa-085602	Oryza sativa	75.00	4.00e-122	430.00
IUUC-Ola-086707	Oryzias latipes	33.95	2.00e-22	98.20
IUUC-Olu-087811	Ostreococcus lucimarinus	43.79	4.00e-35	140.00
IUUC-Oga-088560	Otolemur garnettii	34.83	5.00e-25	107.00
IUUC-Oar-090348	Ovis aries	33.15	3.00e-31	129.00
IUUC-Ptr-091060	Pan troglodytes	32.49	2.00e-28	119.00
IUUC-Pan-091742	Papio anubis	34.29	6.00e-25	107.00
IUUC-Psi-093505	Pelodiscus sinensis	32.95	2.00e-31	129.00
IUUC-Pma-094612	Petromyzon marinus	33.51	4.00e-23	101.00
IUUC-Ppa-095431	Physcomitrella patens	44.99	8.00e-79	286.00
IUUC-Pfo-097396	Poecilia formosa	32.22	5.00e-34	137.00
IUUC-Pab-098591	Pongo abelii	32.49	2.00e-28	119.00
IUUC-Pop-099661	Populus trichocarpa	57.32	2.00e-40	159.00
IUUC-Pca-101029	Procavia capensis	32.81	2.00e-25	109.00
IUUC-Ppe-101495	Prunus persica	66.28	2.00e-51	195.00
IUUC-Pva-102934	Pteropus vampyrus	33.54	3.00e-22	98.60
IUUC-Rno-105861	Rattus norvegicus	36.23	2.00e-19	89.00
IUUC-Sha-107045	Sarcophilus harrisii	32.49	5.00e-30	124.00
IUUC-Smo-109325	Selaginella moellendorffii	49.65	2.00e-31	129.00
IUUC-Sit-110624	Setaria italica	76.20	6.00e-117	413.00
IUUC-Sly-110865	Solanum lycopersicum	88.57	3.00e-33	132.00
IUUC-Stu-112433	Solanum tuberosum	54.91	9.00e-87	312.00
IUUC-Sar-113169	Sorex araneus	42.06	2.00e-19	89.40
IUUC-Sbi-114305	Sorghum bicolor	76.82	2.00e-121	427.00
IUUC-Ssc-115766	Sus scrofa	33.05	4.00e-31	128.00
IUUC-Tgu-116469	Taeniopygia guttata	32.29	4.00e-31	127.00
IUUC-Tru-117732	Takifugu rubripes	31.22	3.00e-30	125.00
IUUC-Tsy-119303	Tarsius syrichta	43.04	6.00e-06	44.70
IUUC-Tni-119852	Tetraodon nigroviridis	30.68	7.00e-28	117.00
IUUC-Tca-121865	Theobroma cacao	65.88	4.00e-51	194.00
IUUC-Tae-123984	Triticum aestivum	99.44	2.00e-167	580.00
IUUC-Tbe-127632	Tupaia belangeri	34.29	8.00e-25	107.00
IUUC-Ttr-128793	Tursiops truncatus	33.33	7.00e-29	120.00
IUUC-Vpa-130625	Vicugna pacos	40.95	1.00e-18	86.70
IUUC-Vvi-131312	Vitis vinifera	51.84	4.00e-93	334.00
IUUC-Xtr-131790	Xenopus tropicalis	36.23	9.00e-21	94.00
IUUC-Xma-133377	Xiphophorus maculatus	32.61	2.00e-17	82.80

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence