iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Sly-111640

Ensembl Protein ID

Solyc04g045480.2.1

UniProt Accession

K4BRH8; K4BRH8_SOLLC

Protein Name

Ubiquitin thioesterase

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
Solyc04g045480.2	Solyc04g045480.2.1	Solyc04g045480.2.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
DUB/OTU	42.01	7.00e-48	188.00	IUUC-Hsa-046766

Active Site

Position(s)	Description	Evidence
92	N/A	{ECO:0000256\|PIRSR:PIRSR013503-1}
95	Nucleophile	{ECO:0000256\|PIRSR:PIRSR013503-1}
294		{ECO:0000256\|PIRSR:PIRSR013503-1}

Organism

Solanum lycopersicum

Protein Sequence
(Fasta)

MQDQDVDVDV ADAAKETFTS SETDDWKKYK DDDIMQQHSA IQAEQAVKVP FLGDKEPLSS 60
LEAEYHLGNS IVLEKIKVLS EQYAAIRRTR GDGNCFFRSF MFGYLEHILE SQDHNEVQHI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GACCCTTGGT ACATCTGCGG GTTGTTTGCT TGCTTGCATG AACTAACCTT TCTTCTCCGG 60
TGGAGGTGGA TGTTCTTGCC TGCGATTCCA CCCAGATCTG AAGGGTAAAG AATATGCCCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway

Interpro

IPR003323--OTU_dom
IPR016615--Otubain
IPR019400--Peptidase_C65_otubain

PROSITE

PS50802--OTU

Pfam

PF10275--Peptidase_C65

Gene Ontology

GO:0005634--C:nucleus
GO:0019784--F:NEDD8-specific protease activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0043130--F:ubiquitin binding
GO:0071108--P:protein K48-linked deubiquitination

KEGG

sly:101267016

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001871	Ailuropoda melanoleuca	42.11	6.00e-49	186.00
IUUC-Apl-003233	Anas platyrhynchos	32.86	1.00e-04	37.00
IUUC-Aca-004648	Anolis carolinensis	40.89	1.00e-44	172.00
IUUC-Aly-005710	Arabidopsis lyrata	71.37	7.00e-115	405.00
IUUC-Ath-007112	Arabidopsis thaliana	69.40	8.00e-113	399.00
IUUC-Afl-008439	Aspergillus flavus	34.78	4.00e-08	50.80
IUUC-Ame-010662	Astyanax mexicanus	42.48	3.00e-49	187.00
IUUC-Bta-013533	Bos taurus	41.73	2.00e-48	184.00
IUUC-Bol-016100	Brassica oleracea	69.17	2.00e-111	394.00
IUUC-Bra-017705	Brassica rapa	62.54	1.00e-103	368.00
IUUC-Cel-018295	Caenorhabditis elegans	34.70	5.00e-40	157.00
IUUC-Cja-019190	Callithrix jacchus	42.11	6.00e-49	186.00
IUUC-Cfa-020430	Canis familiaris	42.11	7.00e-49	186.00
IUUC-Cpo-022355	Cavia porcellus	42.11	4.00e-49	187.00
IUUC-Cre-022997	Chlamydomonas reinhardtii	44.24	4.00e-63	233.00
IUUC-Csa-023286	Chlorocebus sabaeus	40.73	5.00e-47	180.00
IUUC-Cho-024411	Choloepus hoffmanni	37.98	2.00e-16	78.20
IUUC-Cin-025507	Ciona intestinalis	33.51	6.00e-26	109.00
IUUC-Csv-026273	Ciona savignyi	40.46	6.00e-46	176.00
IUUC-Dre-027843	Danio rerio	40.60	1.00e-49	189.00
IUUC-Dno-029165	Dasypus novemcinctus	42.53	3.00e-41	160.00
IUUC-Dor-030943	Dipodomys ordii	42.11	4.00e-49	187.00
IUUC-Dme-031922	Drosophila melanogaster	40.89	6.00e-47	179.00
IUUC-Ete-032266	Echinops telfairi	37.34	2.00e-29	121.00
IUUC-Eca-033695	Equus caballus	42.11	8.00e-49	186.00
IUUC-Eeu-034775	Erinaceus europaeus	37.02	4.00e-34	137.00
IUUC-Fca-036441	Felis catus	42.11	8.00e-49	186.00
IUUC-Gmo-038908	Gadus morhua	41.73	3.00e-48	184.00
IUUC-Ggr-040020	Gaeumannomyces graminis	26.45	5.00e-23	102.00
IUUC-Gga-040460	Gallus gallus	40.60	1.00e-48	185.00
IUUC-Gac-042417	Gasterosteus aculeatus	41.35	2.00e-47	181.00
IUUC-Gma-043712	Glycine max	72.76	4.00e-119	419.00
IUUC-Ggo-045023	Gorilla gorilla	37.02	6.00e-35	139.00
IUUC-Hsa-046766	Homo sapiens	42.11	5.00e-49	187.00
IUUC-Itr-048312	Ictidomys tridecemlineatus	42.11	4.00e-49	187.00
IUUC-Lch-050602	Latimeria chalumnae	39.55	1.00e-40	159.00
IUUC-Loc-052003	Lepisosteus oculatus	32.44	4.00e-30	124.00
IUUC-Laf-053705	Loxodonta africana	42.11	4.00e-49	187.00
IUUC-Mcc-055745	Macaca mulatta	41.73	2.00e-46	177.00
IUUC-Meu-056569	Macropus eugenii	43.44	4.00e-42	163.00
IUUC-Mtr-057712	Medicago truncatula	72.76	2.00e-108	384.00
IUUC-Mla-058941	Melampsora laricipopulina	20.25	5.50e-01	28.10
IUUC-Mvi-060358	Microbotryum violaceum	34.81	2.00e-15	75.50
IUUC-Mmr-061123	Microcebus murinus	42.65	2.00e-40	158.00
IUUC-Mdo-062613	Monodelphis domestica	42.11	9.00e-40	155.00
IUUC-Mmu-063658	Mus musculus	42.11	4.00e-49	187.00
IUUC-Mac-065274	Musa acuminata	50.19	2.00e-67	248.00
IUUC-Mpu-066172	Mustela putorius furo	42.11	5.00e-49	187.00
IUUC-Mlu-066966	Myotis lucifugus	42.11	6.00e-49	186.00
IUUC-Nle-069673	Nomascus leucogenys	37.02	6.00e-35	139.00
IUUC-Opr-070761	Ochotona princeps	33.81	8.00e-13	65.50
IUUC-Ont-071901	Oreochromis niloticus	40.60	2.00e-47	181.00
IUUC-Oan-072922	Ornithorhynchus anatinus	36.75	7.00e-35	139.00
IUUC-Ocu-074643	Oryctolagus cuniculus	36.60	3.00e-34	137.00
IUUC-Oni-082026	Oryza nivara	31.36	9.00e-21	94.00
IUUC-Oru-084761	Oryza rufipogon	31.36	9.00e-21	94.00
IUUC-Ola-087331	Oryzias latipes	40.65	6.00e-33	133.00
IUUC-Oga-088064	Otolemur garnettii	42.11	5.00e-49	187.00
IUUC-Oar-089251	Ovis aries	41.73	4.00e-48	183.00
IUUC-Ptr-091430	Pan troglodytes	42.11	6.00e-49	186.00
IUUC-Pan-091969	Papio anubis	37.02	6.00e-35	139.00
IUUC-Psi-093823	Pelodiscus sinensis	41.26	2.00e-44	171.00
IUUC-Pma-094366	Petromyzon marinus	43.03	1.00e-46	179.00
IUUC-Pfo-096734	Poecilia formosa	40.23	1.00e-42	165.00
IUUC-Pab-097919	Pongo abelii	42.65	6.00e-40	156.00
IUUC-Pop-099401	Populus trichocarpa	72.86	1.00e-114	404.00
IUUC-Pca-100252	Procavia capensis	37.50	1.00e-11	62.40
IUUC-Ppe-101977	Prunus persica	79.48	3.00e-129	453.00
IUUC-Pva-102499	Pteropus vampyrus	42.11	5.00e-49	186.00
IUUC-Rno-105233	Rattus norvegicus	42.11	4.00e-49	187.00
IUUC-Sha-106665	Sarcophilus harrisii	42.86	2.00e-50	191.00
IUUC-Sar-113295	Sorex araneus	36.60	2.00e-34	137.00
IUUC-Ssc-116202	Sus scrofa	42.11	5.00e-49	187.00
IUUC-Tru-117664	Takifugu rubripes	39.85	9.00e-45	172.00
IUUC-Tni-120440	Tetraodon nigroviridis	30.30	8.00e-21	92.80
IUUC-Tca-121467	Theobroma cacao	78.60	7.00e-126	442.00
IUUC-Tbe-128116	Tupaia belangeri	39.59	2.00e-29	122.00
IUUC-Ttr-128622	Tursiops truncatus	42.11	3.00e-49	187.00
IUUC-Uma-129443	Ustilago maydis	28.93	2.00e-27	115.00
IUUC-Vvi-131389	Vitis vinifera	71.96	2.00e-115	407.00
IUUC-Xtr-131951	Xenopus tropicalis	35.93	3.00e-29	120.00
IUUC-Xma-134191	Xiphophorus maculatus	40.60	4.00e-43	167.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence