iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Psi-093203

Ensembl Protein ID

ENSPSIP00000020412.1

UniProt Accession

K7GJF1; K7GJF1_PELSI

Genbank Protein ID

ENSPSIP00000020412

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGCU01129255

Gene Name

UBE3C

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPSIG00000018068.1	ENSPSIT00000020509.1	ENSPSIP00000020412.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	1.70e-54	185.5	746	957

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/HECT

   S: 3    sdlkkrlevefvg.....EegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgr 86
            dlkkr++v++++     E+g+d gG++refl++l+k  +np+ g+f++++++    +p+ ++ + +  + ++++flGr+lgkal+++ 
   Q: 746  PDLKKRIRVHLLNahgldEAGIDGGGIFREFLNELLKSGFNPNQGFFKTTNEGLLYPNPAAQMLVGD-SYARHYYFLGRMLGKALYENM 833
           689**********99**9**************************************9**99999965.9******************** PP
   S: 87   lldlplsksfyklllgk..klsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeY 173
           l++lp++++f+++llg+  ++++++l+++dpe+yk+l ++k++ e d+eelgl++t+   ++ lge++++eLkpgG++ipVt +N+ +Y
   Q: 834  LVELPFASFFLSKLLGTsaDVDIHHLASLDPEMYKNLLFLKSY-EGDVEELGLNFTVV--NNDLGEAQVVELKPGGKDIPVTSANRIAY 919
           ****************9666889******************99.78999987777765..888************************** PP
   S: 174  vklvveyrlkegikeqveafreGfneviplellslFte 211
           ++lv++yrl+++i++++ afr+G+ +v++le+l++F++
   Q: 920  IHLVADYRLNKQIRQHCLAFRQGLANVVNLECLRMFEH 957
           ************************************86 PP

Organism

Pelodiscus sinensis

Protein Sequence
(Fasta)

MFSFEGDFKT RPKVSLGGAS RKEEKASLLH RTQEERRKRE EERRRLKNAI IIQSFVRGYR 60
VRKYQYSIQR SEFDCCANLA QSGGTVSITS GANLTLLVRQ LLFFYRQKED SKRLIWMCQN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNCC 60
GGTGCAGCGT CAGCCTGGGA GGCAGCGGGG ACGCCGCTCT CGATGGGATA AGCTGTAACC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom
IPR000048--IQ_motif_EF-hand-BS

PROSITE

PS50237--HECT
PS50096--IQ

Pfam

PF00632--HECT
PF00612--IQ

SMART

SM00119--HECTc
SM00015--IQ

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity
GO:0000209--P:protein polyubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001355	Ailuropoda melanoleuca	87.21	0.00e+00	1573.00
IUUC-Apl-003731	Anas platyrhynchos	95.24	0.00e+00	1748.00
IUUC-Aca-005248	Anolis carolinensis	93.16	0.00e+00	1754.00
IUUC-Ame-010769	Astyanax mexicanus	59.63	0.00e+00	805.00
IUUC-Bta-012841	Bos taurus	86.13	0.00e+00	1588.00
IUUC-Cel-018638	Caenorhabditis elegans	41.20	2.00e-62	233.00
IUUC-Cja-019743	Callithrix jacchus	86.39	0.00e+00	1581.00
IUUC-Cfa-021031	Canis familiaris	88.44	0.00e+00	1636.00
IUUC-Cpo-022401	Cavia porcellus	87.15	0.00e+00	1604.00
IUUC-Csa-024107	Chlorocebus sabaeus	89.02	0.00e+00	1639.00
IUUC-Cho-024750	Choloepus hoffmanni	76.58	0.00e+00	634.00
IUUC-Cin-025432	Ciona intestinalis	44.41	3.00e-82	298.00
IUUC-Dre-028196	Danio rerio	78.54	0.00e+00	1397.00
IUUC-Dno-029024	Dasypus novemcinctus	90.05	0.00e+00	1662.00
IUUC-Dor-030483	Dipodomys ordii	89.03	0.00e+00	671.00
IUUC-Dme-031946	Drosophila melanogaster	34.69	2.00e-151	529.00
IUUC-Ete-032240	Echinops telfairi	80.77	7.00e-172	597.00
IUUC-Eca-033828	Equus caballus	88.87	0.00e+00	1610.00
IUUC-Eeu-034604	Erinaceus europaeus	83.85	8.00e-126	444.00
IUUC-Fca-035907	Felis catus	87.98	0.00e+00	1635.00
IUUC-Fal-037389	Ficedula albicollis	96.35	0.00e+00	1782.00
IUUC-Gmo-039254	Gadus morhua	71.13	0.00e+00	1245.00
IUUC-Gga-040310	Gallus gallus	94.82	0.00e+00	1763.00
IUUC-Gac-042054	Gasterosteus aculeatus	73.71	0.00e+00	1300.00
IUUC-Ggo-045031	Gorilla gorilla	89.43	0.00e+00	1646.00
IUUC-Hsa-045880	Homo sapiens	89.33	0.00e+00	1645.00
IUUC-Itr-048555	Ictidomys tridecemlineatus	79.91	2.00e-179	621.00
IUUC-Lch-050403	Latimeria chalumnae	83.32	0.00e+00	1561.00
IUUC-Loc-052218	Lepisosteus oculatus	82.94	0.00e+00	1496.00
IUUC-Laf-054162	Loxodonta africana	86.55	0.00e+00	1566.00
IUUC-Mcc-055127	Macaca mulatta	89.12	0.00e+00	1641.00
IUUC-Meu-056187	Macropus eugenii	83.48	2.00e-107	384.00
IUUC-Mga-059581	Meleagris gallopavo	94.58	0.00e+00	1746.00
IUUC-Mmr-061360	Microcebus murinus	84.56	0.00e+00	1488.00
IUUC-Mdo-062194	Monodelphis domestica	89.69	0.00e+00	1727.00
IUUC-Mmu-064189	Mus musculus	87.15	0.00e+00	1624.00
IUUC-Mpu-066439	Mustela putorius furo	87.04	0.00e+00	1575.00
IUUC-Mlu-068228	Myotis lucifugus	84.62	0.00e+00	1574.00
IUUC-Nle-069687	Nomascus leucogenys	88.55	0.00e+00	1587.00
IUUC-Opr-070592	Ochotona princeps	71.10	1.00e-106	380.00
IUUC-Ont-071836	Oreochromis niloticus	79.38	0.00e+00	1434.00
IUUC-Oan-072800	Ornithorhynchus anatinus	94.82	0.00e+00	1765.00
IUUC-Ocu-074587	Oryctolagus cuniculus	89.74	0.00e+00	1658.00
IUUC-Ola-087209	Oryzias latipes	77.72	0.00e+00	1394.00
IUUC-Oga-088776	Otolemur garnettii	83.82	0.00e+00	1474.00
IUUC-Oar-089441	Ovis aries	86.04	0.00e+00	1571.00
IUUC-Ptr-091273	Pan troglodytes	89.22	0.00e+00	1643.00
IUUC-Pan-091981	Papio anubis	89.02	0.00e+00	1640.00
IUUC-Pma-094738	Petromyzon marinus	62.50	0.00e+00	1123.00
IUUC-Pfo-097511	Poecilia formosa	78.49	0.00e+00	1442.00
IUUC-Pab-098634	Pongo abelii	88.60	0.00e+00	1634.00
IUUC-Pca-100987	Procavia capensis	84.01	0.00e+00	693.00
IUUC-Pva-103034	Pteropus vampyrus	82.40	0.00e+00	1472.00
IUUC-Rno-105380	Rattus norvegicus	86.85	0.00e+00	1608.00
IUUC-Sha-107108	Sarcophilus harrisii	85.94	0.00e+00	1571.00
IUUC-Sar-113687	Sorex araneus	79.20	0.00e+00	877.00
IUUC-Ssc-116168	Sus scrofa	82.18	0.00e+00	739.00
IUUC-Tgu-116729	Taeniopygia guttata	95.31	0.00e+00	1757.00
IUUC-Tru-118068	Takifugu rubripes	77.10	0.00e+00	1395.00
IUUC-Tsy-118942	Tarsius syrichta	90.10	0.00e+00	698.00
IUUC-Tni-120732	Tetraodon nigroviridis	76.03	0.00e+00	1355.00
IUUC-Tbe-127351	Tupaia belangeri	76.53	0.00e+00	1298.00
IUUC-Ttr-129061	Tursiops truncatus	84.77	0.00e+00	1538.00
IUUC-Xtr-132094	Xenopus tropicalis	88.00	0.00e+00	1618.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence