iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-054019

UUCD1 version

UUC-LoA-00456

Ensembl Protein ID

ENSLAFP00000011184.4

UniProt Accession

G3TB61; G3TB61_LOXAF

Protein Name

Uncharacterized protein

Gene Name

TRIM40

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000013364.4	ENSLAFT00000013364.4	ENSLAFP00000011184.4
ENSLAFG00000013364.4	ENSLAFT00000027958.1	ENSLAFP00000020117.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.20e-06	29.2	14	55

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C+iC+e++k+ ++ ++CgH+f++ Cl  +    +    ++ CP+Cr
   Q: 14   CSICQEHLKEAVR-TDCGHLFCRVCLALY---LKDCALKAVCPVCR 55
           **********666.************777...344777778****8 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MVPLQEDSRE EGLCSICQEH LKEAVRTDCG HLFCRVCLAL YLKDCALKAV CPVCRAPCSE 60
KVLGEGYICQ SHQERVSLFC EESCLLLCVK CQECPEHQSH RELAIEEAIS HYKERLSRRC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGTTCCTT TGCAGGAGGA CAGTCGAGAG GAGGGCCTTT GCTCCATCTG CCAGGAGCAC 60
TTGAAGGAGG CAGTGAGGAC TGACTGTGGA CACCTCTTCT GTCGAGTGTG CTTGGCCCTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

SMART

SM00184--RING

Gene Ontology

GO:0008385--C:IkappaB kinase complex
GO:0008270--F:zinc ion binding
GO:0032088--P:negative regulation of NF-kappaB transcription factor activity
GO:0042177--P:negative regulation of protein catabolic process
GO:1900181--P:negative regulation of protein localization to nucleus
GO:0045116--P:protein neddylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001427	Ailuropoda melanoleuca	45.02	1.00e-44	172.00
IUUC-Bta-012543	Bos taurus	47.81	1.00e-45	176.00
IUUC-Cja-018793	Callithrix jacchus	50.00	5.00e-49	187.00
IUUC-Csa-023101	Chlorocebus sabaeus	67.12	2.00e-75	275.00
IUUC-Cho-024926	Choloepus hoffmanni	61.97	3.00e-20	92.00
IUUC-Dno-029338	Dasypus novemcinctus	46.98	5.00e-41	160.00
IUUC-Dor-030164	Dipodomys ordii	53.98	3.00e-48	184.00
IUUC-Ete-032446	Echinops telfairi	52.42	2.00e-51	195.00
IUUC-Eca-034042	Equus caballus	57.51	2.00e-61	228.00
IUUC-Eeu-034444	Erinaceus europaeus	47.54	1.00e-46	179.00
IUUC-Ggo-044410	Gorilla gorilla	58.37	2.00e-66	244.00
IUUC-Hsa-045978	Homo sapiens	57.96	7.00e-66	243.00
IUUC-Itr-048126	Ictidomys tridecemlineatus	53.62	2.00e-54	205.00
IUUC-Mcc-054616	Macaca mulatta	59.27	2.00e-71	262.00
IUUC-Meu-055981	Macropus eugenii	46.96	2.00e-25	108.00
IUUC-Mdo-062958	Monodelphis domestica	35.56	2.00e-29	122.00
IUUC-Mmu-063571	Mus musculus	50.43	1.00e-55	209.00
IUUC-Nle-069843	Nomascus leucogenys	51.54	2.00e-21	94.40
IUUC-Opr-071083	Ochotona princeps	47.60	3.00e-52	198.00
IUUC-Ocu-073939	Oryctolagus cuniculus	55.08	8.00e-58	216.00
IUUC-Oga-088040	Otolemur garnettii	58.14	2.00e-65	241.00
IUUC-Oar-089914	Ovis aries	58.09	4.00e-65	241.00
IUUC-Ptr-091240	Pan troglodytes	68.06	2.00e-69	254.00
IUUC-Pan-092095	Papio anubis	57.08	3.00e-60	224.00
IUUC-Pab-098406	Pongo abelii	57.55	1.00e-65	242.00
IUUC-Pca-101043	Procavia capensis	69.16	2.00e-77	281.00
IUUC-Pva-102651	Pteropus vampyrus	58.02	2.00e-69	254.00
IUUC-Rno-106090	Rattus norvegicus	51.48	6.00e-56	210.00
IUUC-Ssc-115942	Sus scrofa	58.96	1.00e-68	253.00
IUUC-Tsy-119497	Tarsius syrichta	55.73	3.00e-65	241.00
IUUC-Tbe-127279	Tupaia belangeri	56.68	2.00e-51	195.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence