iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Apl-003239

Ensembl Protein ID

ENSAPLP00000011781.1

UniProt Accession

U3IX05; U3IX05_ANAPL

Genbank Protein ID

ENSAPLP00000011781

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADON01121662

Gene Name

FBXW8

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAPLG00000012002.1	ENSAPLT00000012512.1	ENSAPLP00000011781.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.20e-15	55.9	385	419

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 6    vtclaf..sd.tllvsGsdDgtikvWDlrtgvllk 37
            tc+++  s  ++lv+G+ D  ++v+Dlr+  +l+
   Q: 385  FTCVNLqdSPpNMLVTGNKDRRVRVYDLRKSESLC 419
           589***97335*****************9987776 PP

Organism

Anas platyrhynchos

Protein Sequence
(Fasta)

GIAQGSVETL LGVFFPPVSS PEQSCCRGSS SSAVPPRRGS PRDGDDLLGQ LIRDLNEINE 60
VPFFDVQLPY ELALKIFQYL GKAELGRCAQ VSRTWKILAE DEVLWYRLCQ QEGYLLDTSI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGTATAGCAC AGGGGTCTGT GGAGACCCTC CTGGGGGTCT TCTTCCCCCC AGTGTCCTCC 60
CCAGAGCAGT CCTGCTGCAG AGGCAGCTCT TCCTCCGCAG TCCCTCCACG GCGGGGCTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR001810--F-box_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50181--FBOX
PS50294--WD_REPEATS_REGION

Pfam

PF12937--F-box-like

SMART

SM00256--FBOX
SM00320--WD40

Gene Ontology

GO:1990393--C:3M complex
GO:0031467--C:Cul7-RING ubiquitin ligase complex
GO:0005829--C:cytosol
GO:0005794--C:Golgi apparatus
GO:0048471--C:perinuclear region of cytoplasm
GO:0019005--C:SCF ubiquitin ligase complex
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008283--P:cell proliferation
GO:0007030--P:Golgi organization
GO:0050775--P:positive regulation of dendrite morphogenesis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001274	Ailuropoda melanoleuca	65.13	0.00e+00	725.00
IUUC-Aca-004756	Anolis carolinensis	74.88	0.00e+00	635.00
IUUC-Ame-011198	Astyanax mexicanus	58.62	2.00e-67	249.00
IUUC-Bta-012430	Bos taurus	44.74	6.00e-112	397.00
IUUC-Cja-019131	Callithrix jacchus	60.71	0.00e+00	640.00
IUUC-Cfa-021022	Canis familiaris	64.81	0.00e+00	704.00
IUUC-Cpo-021898	Cavia porcellus	62.13	0.00e+00	699.00
IUUC-Csa-023452	Chlorocebus sabaeus	58.91	0.00e+00	667.00
IUUC-Cho-024759	Choloepus hoffmanni	55.83	1.00e-172	599.00
IUUC-Dre-028123	Danio rerio	54.98	3.00e-177	614.00
IUUC-Dno-029045	Dasypus novemcinctus	66.09	0.00e+00	652.00
IUUC-Dor-030433	Dipodomys ordii	56.84	2.00e-162	565.00
IUUC-Ete-032465	Echinops telfairi	63.73	4.00e-164	570.00
IUUC-Eca-034134	Equus caballus	65.66	0.00e+00	702.00
IUUC-Eeu-035047	Erinaceus europaeus	56.88	6.00e-172	596.00
IUUC-Fca-036574	Felis catus	65.52	0.00e+00	697.00
IUUC-Fal-037665	Ficedula albicollis	83.23	0.00e+00	849.00
IUUC-Gmo-039137	Gadus morhua	53.36	3.00e-80	291.00
IUUC-Gga-040711	Gallus gallus	93.68	0.00e+00	995.00
IUUC-Gac-041675	Gasterosteus aculeatus	62.96	4.00e-74	270.00
IUUC-Ggo-045331	Gorilla gorilla	61.41	0.00e+00	647.00
IUUC-Hsa-046240	Homo sapiens	61.30	0.00e+00	674.00
IUUC-Itr-048412	Ictidomys tridecemlineatus	65.86	0.00e+00	678.00
IUUC-Loc-052631	Lepisosteus oculatus	63.62	0.00e+00	706.00
IUUC-Laf-054127	Loxodonta africana	61.54	2.00e-47	180.00
IUUC-Mcc-055083	Macaca mulatta	61.30	0.00e+00	670.00
IUUC-Mga-060113	Meleagris gallopavo	92.93	0.00e+00	971.00
IUUC-Mmr-061780	Microcebus murinus	64.88	0.00e+00	703.00
IUUC-Mdo-063066	Monodelphis domestica	80.87	0.00e+00	879.00
IUUC-Mmu-063524	Mus musculus	62.90	0.00e+00	657.00
IUUC-Mpu-066913	Mustela putorius furo	65.81	0.00e+00	714.00
IUUC-Mlu-067924	Myotis lucifugus	62.52	0.00e+00	686.00
IUUC-Nle-069558	Nomascus leucogenys	61.57	0.00e+00	639.00
IUUC-Opr-070506	Ochotona princeps	64.85	0.00e+00	703.00
IUUC-Ont-071514	Oreochromis niloticus	57.06	6.00e-178	617.00
IUUC-Ocu-074477	Oryctolagus cuniculus	65.30	0.00e+00	684.00
IUUC-Ola-087416	Oryzias latipes	56.73	2.00e-173	602.00
IUUC-Oga-088643	Otolemur garnettii	64.50	0.00e+00	710.00
IUUC-Oar-090172	Ovis aries	64.65	0.00e+00	689.00
IUUC-Ptr-090870	Pan troglodytes	62.33	0.00e+00	672.00
IUUC-Pan-092017	Papio anubis	60.73	0.00e+00	662.00
IUUC-Psi-093794	Pelodiscus sinensis	86.34	0.00e+00	915.00
IUUC-Pfo-096192	Poecilia formosa	58.74	0.00e+00	627.00
IUUC-Pab-097882	Pongo abelii	61.93	0.00e+00	662.00
IUUC-Pca-100902	Procavia capensis	63.77	2.00e-103	369.00
IUUC-Pva-103139	Pteropus vampyrus	65.29	0.00e+00	716.00
IUUC-Rno-105798	Rattus norvegicus	63.29	0.00e+00	675.00
IUUC-Sha-106576	Sarcophilus harrisii	80.98	0.00e+00	849.00
IUUC-Ssc-115923	Sus scrofa	59.81	0.00e+00	671.00
IUUC-Tgu-116667	Taeniopygia guttata	79.20	6.00e-173	599.00
IUUC-Tru-118323	Takifugu rubripes	55.19	3.00e-167	581.00
IUUC-Tsy-118818	Tarsius syrichta	43.70	3.00e-102	364.00
IUUC-Tni-120438	Tetraodon nigroviridis	53.58	1.00e-162	566.00
IUUC-Tbe-127784	Tupaia belangeri	57.28	9.00e-136	476.00
IUUC-Ttr-128288	Tursiops truncatus	57.71	3.00e-176	611.00
IUUC-Vpa-130307	Vicugna pacos	61.22	1.00e-168	585.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence