iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-063066

UUCD1 version

UUC-MoD-00226

Ensembl Protein ID

ENSMODP00000019218.3

UniProt Accession

F6TKK9; F6TKK9_MONDO

Protein Name

Uncharacterized protein

Gene Name

FBXW8

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000015392.3	ENSMODT00000019565.3	ENSMODP00000019218.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.10e-12	46.9	502	535

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    HtdsvtclafsdtllvsGsdDgtikvWDlrtgvl 35
           H+ +v++++ +d+ +vsG+  g + vWD r g++
   Q: 502  HQLGVSAVQMDDWKIVSGGEEGLVCVWDQRMGNK 535
           7778999999669***************887765 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MAEAGLEEFR RRWREELALR EGPAKRRRRR SGEEAAGTAR EPEPVSQWSF CGAVQAAPGA 60
PSTQRPGAAT GYFELARSLL EGGESPLIPS SPGIAEEPSC SRQGRIPPTP EAPKPEHPES 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGGCTGCCCG GAACCCAGGG GCTCAGGCAC CTCCGGAGCT CCCAGAACCC GCCCGGAACC 60
CGAGGACCGC GGCGCCGGTT TCCGGCTCTG GTGGCGGACT CTTGTCCTTG AGGGACGGTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR001810--F-box_dom
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50181--FBOX
PS50294--WD_REPEATS_REGION

Pfam

PF12937--F-box-like

SMART

SM00256--FBOX
SM00320--WD40

Gene Ontology

GO:1990393--C:3M complex
GO:0031467--C:Cul7-RING ubiquitin ligase complex
GO:0005829--C:cytosol
GO:0005794--C:Golgi apparatus
GO:0048471--C:perinuclear region of cytoplasm
GO:0019005--C:SCF ubiquitin ligase complex
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008283--P:cell proliferation
GO:0007030--P:Golgi organization
GO:0060716--P:labyrinthine layer blood vessel development
GO:0050775--P:positive regulation of dendrite morphogenesis
GO:0060712--P:spongiotrophoblast layer development

KEGG

mdo:100023212

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001274	Ailuropoda melanoleuca	68.20	0.00e+00	747.00
IUUC-Apl-003239	Anas platyrhynchos	77.26	0.00e+00	864.00
IUUC-Aca-004756	Anolis carolinensis	73.89	1.00e-175	609.00
IUUC-Ame-011198	Astyanax mexicanus	50.95	1.00e-67	249.00
IUUC-Bta-012430	Bos taurus	45.49	3.00e-115	409.00
IUUC-Cja-019131	Callithrix jacchus	63.58	0.00e+00	662.00
IUUC-Cfa-021022	Canis familiaris	68.99	0.00e+00	730.00
IUUC-Cpo-021898	Cavia porcellus	62.90	0.00e+00	726.00
IUUC-Csa-023452	Chlorocebus sabaeus	60.82	0.00e+00	686.00
IUUC-Cho-024759	Choloepus hoffmanni	59.61	2.00e-180	625.00
IUUC-Dre-028123	Danio rerio	55.34	0.00e+00	634.00
IUUC-Dno-029045	Dasypus novemcinctus	69.93	0.00e+00	673.00
IUUC-Dor-030433	Dipodomys ordii	60.25	2.00e-167	582.00
IUUC-Ete-032465	Echinops telfairi	67.32	1.00e-168	586.00
IUUC-Eca-034134	Equus caballus	69.64	0.00e+00	729.00
IUUC-Eeu-035047	Erinaceus europaeus	61.05	1.00e-179	622.00
IUUC-Fca-036574	Felis catus	68.70	0.00e+00	716.00
IUUC-Fal-037665	Ficedula albicollis	73.65	0.00e+00	744.00
IUUC-Gmo-039137	Gadus morhua	48.73	1.00e-77	283.00
IUUC-Gga-040711	Gallus gallus	79.96	0.00e+00	855.00
IUUC-Gac-041675	Gasterosteus aculeatus	70.00	3.00e-79	287.00
IUUC-Ggo-045331	Gorilla gorilla	64.57	0.00e+00	661.00
IUUC-Hsa-046240	Homo sapiens	65.42	0.00e+00	691.00
IUUC-Itr-048412	Ictidomys tridecemlineatus	68.22	0.00e+00	693.00
IUUC-Loc-052631	Lepisosteus oculatus	63.51	0.00e+00	722.00
IUUC-Laf-054127	Loxodonta africana	62.94	6.00e-49	186.00
IUUC-Mcc-055083	Macaca mulatta	65.23	0.00e+00	689.00
IUUC-Mtr-058192	Medicago truncatula	45.45	1.00e-06	45.80
IUUC-Mga-060113	Meleagris gallopavo	80.00	0.00e+00	832.00
IUUC-Mmr-061780	Microcebus murinus	67.86	0.00e+00	720.00
IUUC-Mmu-063524	Mus musculus	64.21	0.00e+00	664.00
IUUC-Mpu-066913	Mustela putorius furo	68.91	0.00e+00	735.00
IUUC-Mlu-067924	Myotis lucifugus	64.29	0.00e+00	720.00
IUUC-Nle-069558	Nomascus leucogenys	66.46	0.00e+00	654.00
IUUC-Opr-070506	Ochotona princeps	67.51	0.00e+00	714.00
IUUC-Ont-071514	Oreochromis niloticus	56.45	0.00e+00	629.00
IUUC-Ocu-074477	Oryctolagus cuniculus	67.70	0.00e+00	690.00
IUUC-Oba-075381	Oryza barthii	41.18	2.00e-07	50.40
IUUC-Obr-076074	Oryza brachyantha	39.71	4.00e-07	49.30
IUUC-Olo-080372	Oryza longistaminata	41.18	2.00e-07	50.40
IUUC-Osa-086065	Oryza sativa	41.18	1.00e-07	50.40
IUUC-Ola-087416	Oryzias latipes	55.11	7.00e-177	613.00
IUUC-Oga-088643	Otolemur garnettii	69.03	0.00e+00	743.00
IUUC-Oar-090172	Ovis aries	68.62	0.00e+00	711.00
IUUC-Ptr-090870	Pan troglodytes	65.42	0.00e+00	691.00
IUUC-Pan-092017	Papio anubis	60.71	0.00e+00	686.00
IUUC-Psi-093794	Pelodiscus sinensis	83.64	0.00e+00	863.00
IUUC-Pfo-096192	Poecilia formosa	56.16	0.00e+00	639.00
IUUC-Pab-097882	Pongo abelii	64.42	0.00e+00	686.00
IUUC-Pca-100902	Procavia capensis	63.19	6.00e-110	391.00
IUUC-Pva-103139	Pteropus vampyrus	69.43	0.00e+00	749.00
IUUC-Rno-105798	Rattus norvegicus	63.65	0.00e+00	681.00
IUUC-Sha-106576	Sarcophilus harrisii	95.90	0.00e+00	967.00
IUUC-Ssc-115923	Sus scrofa	61.54	0.00e+00	696.00
IUUC-Tgu-116667	Taeniopygia guttata	68.53	1.00e-147	515.00
IUUC-Tru-118323	Takifugu rubripes	54.37	6.00e-173	600.00
IUUC-Tsy-118818	Tarsius syrichta	56.25	2.00e-77	282.00
IUUC-Tni-120438	Tetraodon nigroviridis	53.55	2.00e-166	579.00
IUUC-Tbe-127784	Tupaia belangeri	69.71	2.00e-82	299.00
IUUC-Ttr-128288	Tursiops truncatus	61.66	0.00e+00	637.00
IUUC-Vpa-130307	Vicugna pacos	65.58	1.00e-178	619.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence