iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mga-060113

UUCD1 version

UUC-MeG-00452

Ensembl Protein ID

ENSMGAP00000010347.1

UniProt Accession

G1NC97; G1NC97_MELGA

Protein Name

Uncharacterized protein

Gene Name

FBXW8

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000009993.1	ENSMGAT00000011201.1	ENSMGAP00000010347.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	6.90e-15	54.3	382	414

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    HtdsvtclafsdtllvsGsdDgtikvWDlrtgv 34
           H  +v++++ +d+ +vsG+ Dg + vWD r g+
   Q: 382  HRLGVSAVQMDDWKIVSGGEDGLVCVWDQRMGT 414
           6667889999669***************87776 PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

KPKKLYSFFL SYQNEINEVP FFDVHLPYEL ALKIFQYLGK AELGKCAQVS RTWKVLAEDE 60
VLWYRLCQQE GYLLDVSISD RPCWKLALKD CRAKERALRT NWKNRSGAVS QLQYELGKIL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAGCCTAAGA AATTATATTC TTTCTTTTTG TCTTACCAGA ATGAAATCAA TGAGGTTCCT 60
TTCTTTGATG TCCATCTGCC ATACGAACTG GCGTTGAAGA TATTTCAGTA TCTGGGAAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR001810--F-box_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50181--FBOX
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12937--F-box-like

SMART

SM00256--FBOX
SM00320--WD40

Gene Ontology

GO:1990393--C:3M complex
GO:0031467--C:Cul7-RING ubiquitin ligase complex
GO:0005829--C:cytosol
GO:0005794--C:Golgi apparatus
GO:0048471--C:perinuclear region of cytoplasm
GO:0019005--C:SCF ubiquitin ligase complex
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008283--P:cell proliferation
GO:0007030--P:Golgi organization
GO:0050775--P:positive regulation of dendrite morphogenesis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001274	Ailuropoda melanoleuca	65.38	0.00e+00	671.00
IUUC-Apl-003239	Anas platyrhynchos	92.93	0.00e+00	951.00
IUUC-Aca-004756	Anolis carolinensis	74.88	1.00e-178	618.00
IUUC-Ame-011198	Astyanax mexicanus	57.51	8.00e-64	236.00
IUUC-Bta-012430	Bos taurus	42.97	4.00e-101	361.00
IUUC-Cja-019131	Callithrix jacchus	60.81	3.00e-175	608.00
IUUC-Cfa-021022	Canis familiaris	64.50	0.00e+00	667.00
IUUC-Cpo-021898	Cavia porcellus	63.71	0.00e+00	660.00
IUUC-Csa-023452	Chlorocebus sabaeus	61.82	4.00e-180	624.00
IUUC-Cho-024759	Choloepus hoffmanni	55.35	4.00e-156	544.00
IUUC-Dre-028123	Danio rerio	56.16	2.00e-173	602.00
IUUC-Dno-029045	Dasypus novemcinctus	65.43	9.00e-180	622.00
IUUC-Dor-030433	Dipodomys ordii	61.65	3.00e-149	521.00
IUUC-Ete-032465	Echinops telfairi	62.50	2.00e-154	538.00
IUUC-Eca-034134	Equus caballus	65.05	0.00e+00	671.00
IUUC-Eeu-035047	Erinaceus europaeus	56.59	2.00e-163	568.00
IUUC-Fca-036574	Felis catus	64.57	0.00e+00	666.00
IUUC-Fal-037665	Ficedula albicollis	80.81	0.00e+00	793.00
IUUC-Gmo-039137	Gadus morhua	52.31	3.00e-75	275.00
IUUC-Gga-040711	Gallus gallus	98.38	0.00e+00	1019.00
IUUC-Gac-041675	Gasterosteus aculeatus	64.55	5.00e-74	269.00
IUUC-Ggo-045331	Gorilla gorilla	60.79	0.00e+00	627.00
IUUC-Hsa-046240	Homo sapiens	62.22	0.00e+00	631.00
IUUC-Itr-048412	Ictidomys tridecemlineatus	64.44	0.00e+00	640.00
IUUC-Loc-052631	Lepisosteus oculatus	62.85	0.00e+00	675.00
IUUC-Laf-054127	Loxodonta africana	60.14	2.00e-46	176.00
IUUC-Mcc-055083	Macaca mulatta	62.02	0.00e+00	629.00
IUUC-Mmr-061780	Microcebus murinus	64.24	0.00e+00	661.00
IUUC-Mdo-063066	Monodelphis domestica	80.00	0.00e+00	830.00
IUUC-Mmu-063524	Mus musculus	61.02	1.00e-177	615.00
IUUC-Mpu-066913	Mustela putorius furo	65.17	0.00e+00	665.00
IUUC-Mlu-067924	Myotis lucifugus	62.96	0.00e+00	632.00
IUUC-Nle-069558	Nomascus leucogenys	62.13	7.00e-171	593.00
IUUC-Opr-070506	Ochotona princeps	64.57	0.00e+00	654.00
IUUC-Ont-071514	Oreochromis niloticus	57.23	3.00e-172	597.00
IUUC-Ocu-074477	Oryctolagus cuniculus	64.68	0.00e+00	653.00
IUUC-Ola-087416	Oryzias latipes	56.50	3.00e-169	588.00
IUUC-Oga-088643	Otolemur garnettii	64.04	0.00e+00	669.00
IUUC-Oar-090172	Ovis aries	63.47	0.00e+00	662.00
IUUC-Ptr-090870	Pan troglodytes	62.22	0.00e+00	631.00
IUUC-Pan-092017	Papio anubis	61.62	9.00e-180	622.00
IUUC-Psi-093794	Pelodiscus sinensis	85.52	0.00e+00	891.00
IUUC-Pfo-096192	Poecilia formosa	59.30	4.00e-177	613.00
IUUC-Pab-097882	Pongo abelii	61.82	5.00e-180	623.00
IUUC-Pca-100902	Procavia capensis	65.97	6.00e-92	331.00
IUUC-Pva-103139	Pteropus vampyrus	64.44	0.00e+00	669.00
IUUC-Rno-105798	Rattus norvegicus	61.61	0.00e+00	638.00
IUUC-Sha-106576	Sarcophilus harrisii	79.75	0.00e+00	817.00
IUUC-Ssc-115923	Sus scrofa	61.74	6.00e-178	617.00
IUUC-Tgu-116667	Taeniopygia guttata	78.93	2.00e-164	571.00
IUUC-Tru-118323	Takifugu rubripes	55.47	3.00e-165	574.00
IUUC-Tsy-118818	Tarsius syrichta	43.48	6.00e-96	343.00
IUUC-Tni-120438	Tetraodon nigroviridis	55.27	3.00e-159	554.00
IUUC-Tbe-127784	Tupaia belangeri	57.28	1.00e-128	452.00
IUUC-Ttr-128288	Tursiops truncatus	56.48	5.00e-162	563.00
IUUC-Vpa-130307	Vicugna pacos	59.96	2.00e-154	538.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence