iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fal-036726

Ensembl Protein ID

ENSFALP00000015387.1

UniProt Accession

U3KK33; U3KK33_FICAL

Genbank Protein ID

ENSFALP00000015387

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTO01020841

Gene Name

SOCS1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFALG00000014772.1	ENSFALT00000015452.1	ENSFALP00000015387.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	2.20e-13	49.6	161	206

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box

   S: 5    wllrseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlyedyq 53
           +l+  ++ +Lq+LCR++I++++g+++l   +++PL+++LkdYL+++++q
   Q: 161  PLRKVRVQPLQELCRKSIVKTFGKENL---NQIPLNPVLKDYLKSFPFQ 206
           5566689********************...****************986 PP

Organism

Ficedula albicollis

Protein Sequence
(Fasta)

MVAHSKVSAD NALGADPRRL LDPPARDRSQ ARGFQGPGRP GTVQAQGNTH FRTFRSQADF 60
SSITRASSLL DACGFYWGPL SVSAAHEKLK SEPEGTFLIR DSTQKNCFFA ISVKTATGPT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGTAGCGC ACAGCAAGGT GTCAGCAGAT AATGCACTTG GAGCAGACCC AAGACGGCTT 60
CTTGACCCCC CGGCACGGGA TCGCTCACAG GCACGAGGCT TCCAGGGCCC CGGCCGGCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000980--SH2
IPR028411--SOCS1
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2
PF07525--SOCS_box

SMART

SM00252--SH2
SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0000932--C:P-body
GO:0019210--F:kinase inhibitor activity
GO:0071230--P:cellular response to amino acid stimulus
GO:0019221--P:cytokine-mediated signaling pathway
GO:0045444--P:fat cell differentiation
GO:0007259--P:JAK-STAT cascade
GO:0046627--P:negative regulation of insulin receptor signaling pathway
GO:0042512--P:negative regulation of tyrosine phosphorylation of Stat1 protein
GO:0042518--P:negative regulation of tyrosine phosphorylation of Stat3 protein
GO:0016567--P:protein ubiquitination
GO:0010534--P:regulation of activation of JAK2 kinase activity
GO:0050707--P:regulation of cytokine secretion
GO:0060334--P:regulation of interferon-gamma-mediated signaling pathway

KEGG

fab:101818258

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001204	Ailuropoda melanoleuca	65.62	1.00e-61	228.00
IUUC-Apl-003313	Anas platyrhynchos	94.69	9.00e-116	408.00
IUUC-Aca-005109	Anolis carolinensis	68.99	1.00e-64	238.00
IUUC-Ame-011550	Astyanax mexicanus	59.63	9.00e-57	212.00
IUUC-Bta-013411	Bos taurus	72.05	1.00e-72	265.00
IUUC-Cja-019595	Callithrix jacchus	72.67	5.00e-73	266.00
IUUC-Cfa-020563	Canis familiaris	71.43	5.00e-72	263.00
IUUC-Cpo-021374	Cavia porcellus	72.05	1.00e-72	265.00
IUUC-Csa-023333	Chlorocebus sabaeus	73.29	1.00e-73	268.00
IUUC-Dre-028507	Danio rerio	47.55	2.00e-50	191.00
IUUC-Dno-029406	Dasypus novemcinctus	62.02	6.00e-73	266.00
IUUC-Ete-032399	Echinops telfairi	60.77	1.00e-71	261.00
IUUC-Eca-033519	Equus caballus	61.61	1.00e-69	255.00
IUUC-Gmo-039667	Gadus morhua	42.48	5.00e-24	103.00
IUUC-Gga-040970	Gallus gallus	93.24	3.00e-113	400.00
IUUC-Gac-041838	Gasterosteus aculeatus	44.44	4.00e-37	147.00
IUUC-Ggo-045569	Gorilla gorilla	60.39	2.00e-73	267.00
IUUC-Hsa-046010	Homo sapiens	72.67	4.00e-73	266.00
IUUC-Itr-047995	Ictidomys tridecemlineatus	72.67	6.00e-73	266.00
IUUC-Lch-050219	Latimeria chalumnae	68.32	6.00e-66	242.00
IUUC-Loc-052494	Lepisosteus oculatus	57.97	6.00e-66	243.00
IUUC-Laf-054219	Loxodonta africana	71.32	8.00e-57	211.00
IUUC-Mcc-054830	Macaca mulatta	73.29	1.00e-73	268.00
IUUC-Meu-056565	Macropus eugenii	75.59	5.00e-91	326.00
IUUC-Mga-060153	Meleagris gallopavo	92.75	2.00e-103	367.00
IUUC-Mmr-061365	Microcebus murinus	72.67	5.00e-73	266.00
IUUC-Mdo-062824	Monodelphis domestica	73.83	3.00e-88	317.00
IUUC-Mmu-064120	Mus musculus	71.43	5.00e-72	263.00
IUUC-Mpu-066839	Mustela putorius furo	72.67	4.00e-73	266.00
IUUC-Mlu-067829	Myotis lucifugus	70.81	1.00e-71	261.00
IUUC-Nle-069592	Nomascus leucogenys	61.54	9.00e-71	259.00
IUUC-Ont-072173	Oreochromis niloticus	47.50	6.00e-39	153.00
IUUC-Ocu-073996	Oryctolagus cuniculus	72.67	1.00e-72	265.00
IUUC-Ola-087158	Oryzias latipes	49.69	2.00e-40	158.00
IUUC-Oga-088076	Otolemur garnettii	62.74	5.00e-73	266.00
IUUC-Ptr-091241	Pan troglodytes	72.67	4.00e-73	266.00
IUUC-Pan-091836	Papio anubis	61.84	2.00e-74	271.00
IUUC-Psi-093628	Pelodiscus sinensis	86.96	1.00e-106	378.00
IUUC-Pfo-097501	Poecilia formosa	44.03	3.00e-36	144.00
IUUC-Pab-098170	Pongo abelii	72.67	4.00e-73	266.00
IUUC-Pop-100072	Populus trichocarpa	30.00	2.30e-01	29.30
IUUC-Pva-102796	Pteropus vampyrus	72.05	1.00e-72	265.00
IUUC-Pgr-103356	Puccinia graminis	25.24	3.30e-01	28.90
IUUC-Rno-105319	Rattus norvegicus	71.43	5.00e-72	263.00
IUUC-Sha-107201	Sarcophilus harrisii	83.77	8.00e-77	278.00
IUUC-Ssc-116004	Sus scrofa	60.45	6.00e-76	276.00
IUUC-Tgu-116836	Taeniopygia guttata	97.10	7.00e-118	415.00
IUUC-Tru-118090	Takifugu rubripes	46.58	4.00e-37	147.00
IUUC-Tni-120719	Tetraodon nigroviridis	46.58	4.00e-33	134.00
IUUC-Vpa-130235	Vicugna pacos	72.67	5.00e-73	266.00
IUUC-Xtr-132610	Xenopus tropicalis	65.40	4.00e-78	283.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence