iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Eca-033456

Ensembl Protein ID

ENSECAP00000018502.1

UniProt Accession

F6WA05; F6WA05_HORSE

Protein Name

Uncharacterized protein

Gene Name

SQSTM1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000020929.1	ENSECAT00000022389.1	ENSECAP00000018502.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/UBA	47.17	3.00e-08	56.60	IUUC-Dme-031659
UBD/Alpha-Helix/UBA	90.86	0.00e+00	676.00	IUUC-Hsa-046390
ULD/UDP/UFD/PB1	90.86	0.00e+00	676.00	IUUC-Hsa-046390
UBD/Alpha-Helix/UBA	88.31	0.00e+00	676.00	IUUC-Mmu-063589
UBD/Alpha-Helix/UBA	88.05	0.00e+00	667.00	IUUC-Rno-105539

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Equus caballus

Protein Sequence
(Fasta)

XQAHYRDEDG DLVAFSSDEE LTMALSYVKD DIFRIYIKEK KECRRDHRPP CAQEAPRNMV 60
HPNVICDGCN GPVVGTRYKC SVCPDYDLCA SCEGKGMHRE HSKLAFPSPF GHLSEGFSHS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

NTCCAGGCGC ACTACCGCGG TGTAGCGGGC GGCGCCCTCG GGCGGCGCGG GCCGTGACGC 60
AGGCGGCCCG CGAGGTGGCC GTTCTTGCTT GTCGTCGGGC CCGGTGGTGT CTGCGGGGGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR000270--PB1_dom
IPR033741--SQSTM_UBA
IPR015940--UBA
IPR009060--UBA-like
IPR000433--Znf_ZZ

PROSITE

PS51745--PB1
PS50030--UBA
PS01357--ZF_ZZ_1
PS50135--ZF_ZZ_2

Pfam

PF00564--PB1
PF16577--UBA_5
PF00569--ZZ

SMART

SM00165--UBA
SM00291--ZnF_ZZ

Gene Ontology

GO:0016235--C:aggresome
GO:0044753--C:amphisome
GO:0044754--C:autolysosome
GO:0005776--C:autophagosome
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0000932--C:P-body
GO:0016605--C:PML body
GO:0000407--C:pre-autophagosomal structure
GO:0097225--C:sperm midpiece
GO:0042802--F:identical protein binding
GO:0043130--F:ubiquitin binding
GO:0008270--F:zinc ion binding
GO:0006914--P:autophagy
GO:0044130--P:negative regulation of growth of symbiont in host
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0016239--P:positive regulation of macroautophagy
GO:0098779--P:positive regulation of macromitophagy in response to mitochondrial depolarization
GO:0043122--P:regulation of I-kappaB kinase/NF-kappaB signaling
GO:0061635--P:regulation of protein complex stability
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001367	Ailuropoda melanoleuca	90.74	6.00e-175	606.00
IUUC-Apl-003897	Anas platyrhynchos	56.45	2.00e-114	405.00
IUUC-Aca-004699	Anolis carolinensis	49.49	4.00e-87	314.00
IUUC-Ame-010982	Astyanax mexicanus	43.40	1.00e-65	243.00
IUUC-Bta-012634	Bos taurus	90.60	0.00e+00	674.00
IUUC-Cel-018660	Caenorhabditis elegans	47.73	3.00e-11	61.20
IUUC-Cja-019684	Callithrix jacchus	89.30	0.00e+00	641.00
IUUC-Cfa-020573	Canis familiaris	84.64	2.00e-143	501.00
IUUC-Cpo-021425	Cavia porcellus	80.36	2.00e-158	552.00
IUUC-Csa-023968	Chlorocebus sabaeus	89.30	0.00e+00	633.00
IUUC-Cho-024596	Choloepus hoffmanni	80.75	4.00e-52	198.00
IUUC-Cin-025557	Ciona intestinalis	57.14	2.00e-09	56.60
IUUC-Csv-025974	Ciona savignyi	57.50	6.00e-09	54.70
IUUC-Cne-027045	Cryptococcus neoformans	50.98	8.00e-10	59.70
IUUC-Dre-028621	Danio rerio	45.13	3.00e-87	315.00
IUUC-Dno-029060	Dasypus novemcinctus	86.79	0.00e+00	655.00
IUUC-Dor-030547	Dipodomys ordii	91.83	2.00e-115	409.00
IUUC-Dme-031659	Drosophila melanogaster	47.17	4.00e-09	56.20
IUUC-Ete-033201	Echinops telfairi	79.31	8.00e-165	572.00
IUUC-Eeu-035157	Erinaceus europaeus	84.43	2.00e-175	607.00
IUUC-Fca-035403	Felis catus	90.86	0.00e+00	632.00
IUUC-Fal-036798	Ficedula albicollis	58.09	5.00e-122	431.00
IUUC-Gmo-039619	Gadus morhua	45.32	1.00e-43	169.00
IUUC-Gga-040137	Gallus gallus	56.62	6.00e-120	424.00
IUUC-Gac-042410	Gasterosteus aculeatus	48.46	2.00e-87	315.00
IUUC-Ggo-044690	Gorilla gorilla	90.86	0.00e+00	639.00
IUUC-Hsa-046390	Homo sapiens	90.86	0.00e+00	639.00
IUUC-Itr-048536	Ictidomys tridecemlineatus	91.38	0.00e+00	691.00
IUUC-Lch-049658	Latimeria chalumnae	48.50	1.00e-102	366.00
IUUC-Loc-052589	Lepisosteus oculatus	48.02	6.00e-100	357.00
IUUC-Laf-053746	Loxodonta africana	76.86	1.00e-160	558.00
IUUC-Mcc-055635	Macaca mulatta	89.56	0.00e+00	641.00
IUUC-Meu-056528	Macropus eugenii	48.44	6.00e-92	330.00
IUUC-Mga-059458	Meleagris gallopavo	57.53	3.00e-118	418.00
IUUC-Mvi-060347	Microbotryum violaceum	48.84	1.00e-07	52.40
IUUC-Mmr-061539	Microcebus murinus	86.61	4.00e-116	410.00
IUUC-Mdo-063083	Monodelphis domestica	64.71	5.00e-134	471.00
IUUC-Mmu-063589	Mus musculus	87.53	0.00e+00	660.00
IUUC-Mpu-065727	Mustela putorius furo	89.12	0.00e+00	636.00
IUUC-Mlu-067026	Myotis lucifugus	88.19	0.00e+00	644.00
IUUC-Nle-069356	Nomascus leucogenys	59.54	1.00e-94	340.00
IUUC-Opr-071091	Ochotona princeps	70.83	2.00e-87	316.00
IUUC-Ont-071864	Oreochromis niloticus	49.48	3.00e-94	338.00
IUUC-Oan-073308	Ornithorhynchus anatinus	66.84	2.00e-131	462.00
IUUC-Ocu-074110	Oryctolagus cuniculus	90.41	0.00e+00	660.00
IUUC-Ola-086944	Oryzias latipes	44.49	8.00e-38	149.00
IUUC-Oga-088869	Otolemur garnettii	88.17	0.00e+00	641.00
IUUC-Oar-089857	Ovis aries	90.55	0.00e+00	661.00
IUUC-Ptr-091640	Pan troglodytes	90.86	0.00e+00	639.00
IUUC-Pan-092831	Papio anubis	88.95	0.00e+00	632.00
IUUC-Psi-093925	Pelodiscus sinensis	57.80	2.00e-115	409.00
IUUC-Pma-094576	Petromyzon marinus	32.92	4.00e-25	108.00
IUUC-Pfo-097297	Poecilia formosa	44.69	1.00e-80	293.00
IUUC-Pab-098725	Pongo abelii	79.63	2.00e-158	551.00
IUUC-Pca-101106	Procavia capensis	89.30	6.00e-180	623.00
IUUC-Pva-102710	Pteropus vampyrus	87.31	5.00e-161	560.00
IUUC-Rno-105539	Rattus norvegicus	88.05	0.00e+00	668.00
IUUC-Sha-107469	Sarcophilus harrisii	58.96	7.00e-122	430.00
IUUC-Ssc-115526	Sus scrofa	92.17	0.00e+00	661.00
IUUC-Tgu-117194	Taeniopygia guttata	58.84	4.00e-118	417.00
IUUC-Tru-117896	Takifugu rubripes	48.97	7.00e-91	327.00
IUUC-Tni-119943	Tetraodon nigroviridis	50.39	2.00e-84	305.00
IUUC-Ttr-128676	Tursiops truncatus	91.12	0.00e+00	691.00
IUUC-Vda-129812	Verticillium dahliae	37.66	1.00e-07	51.60
IUUC-Vpa-130319	Vicugna pacos	96.00	3.00e-57	214.00
IUUC-Xtr-132907	Xenopus tropicalis	54.85	2.00e-116	412.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence