iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-033542

UUCD1 version

UUC-EqC-00184

Ensembl Protein ID

ENSECAP00000003877.1

UniProt Accession

F6SJZ3; F6SJZ3_HORSE

Protein Name

Uncharacterized protein

Gene Name

KLHL4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000002157.1	ENSECAT00000005504.1	ENSECAP00000003877.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	3.30e-17	62.8	182	249
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	6.60e-06	25.5	281	311

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkldene 69
           +Dv+l+ g  +++ah++vL+a S++F a+f+++  e k +++v +++v+p +++ l+++ Ytg l+++e
   Q: 182  CDVLLIAGHLRIPAHRLVLSAVSDYFAAMFTNDVLEAK-QEEVRMEGVDPNALNSLVQYAYTGVLQLKE 249
           8************************************9.**************************9986 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhF 31
           ++Nclgi++f+d+ +c +L  +a++++  hF
   Q: 281  PSNCLGIRSFGDAQGCMELLNVAHKYTMEHF 311
           89************************98777 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

MSVSGKKEFD VKQILRLRWR WFSHPSQGSP NTGNCLQQEG YEHRGTPVQG RLKNHSRDRN 60
GLKKSNSPVH HNILVPVPGP SPAHQRALQN WHPLNLIEHL RANEDTPKAV PEENLFKEAC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGGTTGGGG GGAAGCAAGA AAGACTGCTC TCGGCGCTTG TGCTTTTGTT AGTTCTACAG 60
AAGAGGGAGA GAAACAAGAG ATAACAAAGG CTCCGTTTCC TTTCTGTGAG AGAAGGCTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005815--C:microtubule organizing center
GO:0016567--P:protein ubiquitination

KEGG

ecb:100071689

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001422	Ailuropoda melanoleuca	90.99	0.00e+00	1287.00
IUUC-Apl-004156	Anas platyrhynchos	82.74	0.00e+00	983.00
IUUC-Aca-004238	Anolis carolinensis	77.84	0.00e+00	1123.00
IUUC-Ame-011287	Astyanax mexicanus	69.74	0.00e+00	901.00
IUUC-Bta-013232	Bos taurus	89.41	0.00e+00	1154.00
IUUC-Cja-018916	Callithrix jacchus	90.41	0.00e+00	1281.00
IUUC-Cfa-020972	Canis familiaris	91.87	0.00e+00	1073.00
IUUC-Csa-023849	Chlorocebus sabaeus	90.95	0.00e+00	1325.00
IUUC-Dor-030708	Dipodomys ordii	84.69	0.00e+00	1201.00
IUUC-Ete-033156	Echinops telfairi	80.43	0.00e+00	814.00
IUUC-Fal-036999	Ficedula albicollis	79.42	0.00e+00	1161.00
IUUC-Fox-038050	Fusarium oxysporum	27.27	4.00e-07	48.50
IUUC-Gmo-039532	Gadus morhua	80.28	0.00e+00	917.00
IUUC-Gga-040215	Gallus gallus	80.97	0.00e+00	1195.00
IUUC-Gac-041582	Gasterosteus aculeatus	80.11	0.00e+00	935.00
IUUC-Ggo-045074	Gorilla gorilla	91.09	0.00e+00	1331.00
IUUC-Hsa-046486	Homo sapiens	91.01	0.00e+00	1299.00
IUUC-Lch-050265	Latimeria chalumnae	81.29	0.00e+00	959.00
IUUC-Loc-052015	Lepisosteus oculatus	76.81	0.00e+00	1083.00
IUUC-Laf-053627	Loxodonta africana	89.69	0.00e+00	1313.00
IUUC-Mcc-055418	Macaca mulatta	91.09	0.00e+00	1332.00
IUUC-Meu-056859	Macropus eugenii	75.07	7.00e-150	523.00
IUUC-Mga-059582	Meleagris gallopavo	80.65	0.00e+00	1127.00
IUUC-Mmr-061648	Microcebus murinus	91.92	0.00e+00	1340.00
IUUC-Mdo-062785	Monodelphis domestica	83.86	0.00e+00	958.00
IUUC-Mmu-063807	Mus musculus	86.75	0.00e+00	1263.00
IUUC-Mpu-066279	Mustela putorius furo	90.48	0.00e+00	1056.00
IUUC-Mlu-067981	Myotis lucifugus	89.69	0.00e+00	1321.00
IUUC-Nle-070033	Nomascus leucogenys	91.13	0.00e+00	1295.00
IUUC-Ont-071932	Oreochromis niloticus	73.09	0.00e+00	1065.00
IUUC-Ocu-073854	Oryctolagus cuniculus	92.99	0.00e+00	1093.00
IUUC-Ola-087436	Oryzias latipes	72.31	0.00e+00	1027.00
IUUC-Oar-089952	Ovis aries	90.39	0.00e+00	1314.00
IUUC-Ptr-091649	Pan troglodytes	84.26	0.00e+00	1173.00
IUUC-Pan-091798	Papio anubis	91.23	0.00e+00	1332.00
IUUC-Psi-093728	Pelodiscus sinensis	79.58	0.00e+00	1178.00
IUUC-Pfo-096954	Poecilia formosa	73.42	0.00e+00	1052.00
IUUC-Pab-098461	Pongo abelii	90.39	0.00e+00	1313.00
IUUC-Pva-102458	Pteropus vampyrus	91.59	0.00e+00	1192.00
IUUC-Rno-105865	Rattus norvegicus	87.17	0.00e+00	1265.00
IUUC-Sha-107322	Sarcophilus harrisii	82.60	0.00e+00	952.00
IUUC-Ssc-116001	Sus scrofa	93.56	0.00e+00	1367.00
IUUC-Tgu-116994	Taeniopygia guttata	80.67	0.00e+00	1181.00
IUUC-Tru-117780	Takifugu rubripes	80.14	0.00e+00	919.00
IUUC-Tni-120794	Tetraodon nigroviridis	70.60	0.00e+00	988.00
IUUC-Tbe-128118	Tupaia belangeri	75.82	0.00e+00	966.00
IUUC-Vpa-130811	Vicugna pacos	89.02	0.00e+00	1258.00
IUUC-Xtr-132358	Xenopus tropicalis	77.52	0.00e+00	1147.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence