iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ssc-116001

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

CU606856

Gene Name

KLHL4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSSCG00000012467.2	ENSSSCT00000013634.2	ENSSSCP00000013266.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	2.80e-17	63.1	182	249
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	6.80e-07	28.6	281	311

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkldene 69
           +Dv+l+ g  +++ah++vL+a S++F a+f+++  e k +++v++++++p +++ l+++ Ytg l+++e
   Q: 182  CDVLLIAGHLRIPAHRLVLSAVSDYFAAMFTNDVLEAK-QEEVKMEGIDPNALNSLVQYAYTGVLQLKE 249
           8************************************9.**************************9986 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhF 31
           ++Nclgi++f+d+ +c++L ++a++++  hF
   Q: 281  PSNCLGIRSFGDAQGCTELLSVAHKYTMEHF 311
           89************************98777 PP

Organism

Sus scrofa

Protein Sequence
(Fasta)

MSVSGKKEFD VKQILRLRWR WFSHPSQGSP NTGNCLQQEG YEHRGTPVQG RLKSHPRDRN 60
GLKKSNSPVH HSILAPVPGP APAHQRALQN WHPQNLIEHL QANEDTPKAV PEENLFKKSC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCAGCTGAAG CCAGAAGTAT TCACAGTGTA CCACAGACAG CAGGGGAGGG GGGAGGAAGA 60
AAGACTGCTC TCTGCACTTG TGCTTTTGTT AGTCCACAGA AGAGGCAGAG AAACAAGAGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005815--C:microtubule organizing center
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001422	Ailuropoda melanoleuca	93.13	0.00e+00	1328.00
IUUC-Apl-004156	Anas platyrhynchos	86.19	0.00e+00	998.00
IUUC-Aca-004238	Anolis carolinensis	79.81	0.00e+00	1144.00
IUUC-Ame-011287	Astyanax mexicanus	71.34	0.00e+00	920.00
IUUC-Bta-013232	Bos taurus	91.90	0.00e+00	1191.00
IUUC-Cja-018916	Callithrix jacchus	92.27	0.00e+00	1321.00
IUUC-Cfa-020972	Canis familiaris	95.47	0.00e+00	1112.00
IUUC-Csa-023849	Chlorocebus sabaeus	93.00	0.00e+00	1358.00
IUUC-Dor-030708	Dipodomys ordii	85.84	0.00e+00	1229.00
IUUC-Dme-032222	Drosophila melanogaster	54.06	6.00e-177	613.00
IUUC-Ete-033156	Echinops telfairi	81.78	0.00e+00	833.00
IUUC-Eca-033542	Equus caballus	93.56	0.00e+00	1341.00
IUUC-Fal-036999	Ficedula albicollis	80.70	0.00e+00	1173.00
IUUC-Fox-038050	Fusarium oxysporum	27.27	3.00e-07	48.50
IUUC-Gmo-039532	Gadus morhua	81.59	0.00e+00	926.00
IUUC-Gga-040215	Gallus gallus	82.40	0.00e+00	1211.00
IUUC-Gac-041582	Gasterosteus aculeatus	81.06	0.00e+00	941.00
IUUC-Ggo-045074	Gorilla gorilla	93.28	0.00e+00	1367.00
IUUC-Hsa-046486	Homo sapiens	93.15	0.00e+00	1342.00
IUUC-Lch-050265	Latimeria chalumnae	81.30	0.00e+00	970.00
IUUC-Loc-052015	Lepisosteus oculatus	78.35	0.00e+00	1095.00
IUUC-Laf-053627	Loxodonta africana	92.01	0.00e+00	1342.00
IUUC-Mcc-055418	Macaca mulatta	93.14	0.00e+00	1364.00
IUUC-Meu-056859	Macropus eugenii	76.16	2.00e-151	528.00
IUUC-Mga-059582	Meleagris gallopavo	82.15	0.00e+00	1143.00
IUUC-Mmr-061648	Microcebus murinus	93.98	0.00e+00	1376.00
IUUC-Mdo-062785	Monodelphis domestica	85.69	0.00e+00	971.00
IUUC-Mmu-063807	Mus musculus	88.38	0.00e+00	1288.00
IUUC-Mpu-066279	Mustela putorius furo	93.21	0.00e+00	1090.00
IUUC-Mlu-067981	Myotis lucifugus	90.90	0.00e+00	1340.00
IUUC-Nle-070033	Nomascus leucogenys	92.99	0.00e+00	1335.00
IUUC-Ont-071932	Oreochromis niloticus	75.55	0.00e+00	1077.00
IUUC-Ocu-073854	Oryctolagus cuniculus	94.36	0.00e+00	1118.00
IUUC-Oin-079973	Oryza indica	31.47	2.00e-34	140.00
IUUC-Ola-087436	Oryzias latipes	73.86	0.00e+00	1044.00
IUUC-Oar-089952	Ovis aries	93.42	0.00e+00	1358.00
IUUC-Ptr-091649	Pan troglodytes	86.41	0.00e+00	1202.00
IUUC-Pan-091798	Papio anubis	93.28	0.00e+00	1364.00
IUUC-Psi-093728	Pelodiscus sinensis	81.28	0.00e+00	1194.00
IUUC-Pfo-096954	Poecilia formosa	74.79	0.00e+00	1066.00
IUUC-Pab-098461	Pongo abelii	92.58	0.00e+00	1350.00
IUUC-Pva-102458	Pteropus vampyrus	93.77	0.00e+00	1229.00
IUUC-Rno-105865	Rattus norvegicus	89.22	0.00e+00	1293.00
IUUC-Sha-107322	Sarcophilus harrisii	84.60	0.00e+00	961.00
IUUC-Tgu-116994	Taeniopygia guttata	81.96	0.00e+00	1192.00
IUUC-Tru-117780	Takifugu rubripes	81.42	0.00e+00	925.00
IUUC-Tni-120794	Tetraodon nigroviridis	72.98	0.00e+00	1000.00
IUUC-Tca-120913	Theobroma cacao	34.18	6.00e-34	139.00
IUUC-Tbe-128118	Tupaia belangeri	76.44	0.00e+00	983.00
IUUC-Ttr-129220	Tursiops truncatus	87.55	0.00e+00	1251.00
IUUC-Vpa-130811	Vicugna pacos	90.73	0.00e+00	1287.00
IUUC-Xtr-132358	Xenopus tropicalis	78.92	0.00e+00	1160.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence