iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000020107.9	ENSDART00000134053.3	ENSDARP00000119800.1
ENSDARG00000020107.9	ENSDART00000152371.2	ENSDARP00000126710.1
ENSDARG00000020107.9	ENSDART00000152648.2	ENSDARP00000126829.1
ENSDARG00000020107.9	ENSDART00000165816.1	ENSDARP00000129875.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	5.90e-104	348.8	61	391

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelw.kskkkavsprellkalkkeaeefsgy 87
           +Gl+NlgNtC+mNS+LQcLsn+++lr+++l+ +++++ln++  + ++++l+++++kl++ +w +s+++avsp+e++++++++a++f gy
   Q: 61   VGLRNLGNTCFMNSILQCLSNTQSLRDYCLHnSHRRDLNNN--NRTHTALMEEFAKLIQTMWtSSSSEAVSPSEFKTQIQRYAPRFVGY 147
           6******************************5555555555..6799***************9999*********************** PP
   S: 88   eqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde.....aeekkkkknkslisdlFqgqlksqikclecdnvssreepfld 171
           +qqDaqEfl+flld+l++e+++ +  p+ ++e+ d+    de      ++k  ++++s i+dlF gqlks+++c ec+  s+ ++pf+d
   Q: 148  NQQDAQEFLRFLLDGLHNEVNRVTVRPRGNTEDFDHLP--DEekgkkMWSKYLEREDSKIVDLFVGQLKSSLTCSECGYCSTVFDPFWD 234
           **********************7777777777766433..33335559***************************************** PP
   S: 172  lslpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple.L 259
           lslp+ +     + sl dc++ ftke+ l+g++k  c +ck++++++kk++++k+P++L+lhLkRf  se++ + +k+++ v+fp + L
   Q: 235  LSLPIAKGYG--EVSLMDCMRLFTKEDVLDGDEKPTCYRCKARRRCTKKFTVQKFPKILVLHLKRF--SEARIRTSKLSTFVNFPMKdL 319
           *****97774..46****************************************************..9999**************99* PP
   S: 260  dlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtevkeeevleetgstaYvlfYkr 337
           dl++f +++++    +  Y+L+av +HsG++ +GHY+ay+ n +++ W++++Ds+Vt+++ ++v +   s+aYvlfY+r
   Q: 320  DLREFASDRSS----SAVYNLYAVSNHSGTTMGGHYTAYCCNPENGeWYTYNDSRVTPMSASQVRS---SDAYVLFYER 391
           ******99554....68*************************66655*******************...********98 PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MPSMRHSYTV TIPEEPPATA LSLLKQDMRR KNSVSGSMLV STFVGLLINH AKNSKSAQGL 60
VGLRNLGNTC FMNSILQCLS NTQSLRDYCL HNSHRRDLNN NNRTHTALME EFAKLIQTMW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGACCGTTTT TCTTTGACTA CAAGTCAAGA GCTTGGATTA ATACGAGGGC ATAAGCAAGC 60
AAAATGTACC CGTCTGTGCT GTTTTGAGCA CTGGTGAACT GTCGTGTGTG GTCTGGAGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

dre:494031

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001988	Ailuropoda melanoleuca	81.82	1.00e-159	556.00
IUUC-Aca-005132	Anolis carolinensis	79.18	2.00e-162	565.00
IUUC-Bta-012529	Bos taurus	74.48	6.00e-152	531.00
IUUC-Cja-019016	Callithrix jacchus	78.26	7.00e-149	521.00
IUUC-Cfa-020714	Canis familiaris	81.52	6.00e-159	554.00
IUUC-Cpo-021727	Cavia porcellus	80.35	9.00e-157	546.00
IUUC-Csa-023071	Chlorocebus sabaeus	81.16	8.00e-160	556.00
IUUC-Dno-029329	Dasypus novemcinctus	80.06	5.00e-166	577.00
IUUC-Dor-030574	Dipodomys ordii	81.52	3.00e-156	545.00
IUUC-Eca-033361	Equus caballus	81.82	2.00e-159	556.00
IUUC-Eeu-035272	Erinaceus europaeus	83.06	7.00e-80	291.00
IUUC-Fca-036497	Felis catus	81.82	1.00e-159	556.00
IUUC-Fal-036766	Ficedula albicollis	80.70	6.00e-157	547.00
IUUC-Gga-040889	Gallus gallus	77.07	9.00e-154	536.00
IUUC-Ggo-044814	Gorilla gorilla	73.39	7.00e-139	486.00
IUUC-Hsa-045937	Homo sapiens	80.94	8.00e-158	550.00
IUUC-Itr-048171	Ictidomys tridecemlineatus	80.64	1.00e-159	556.00
IUUC-Lch-050527	Latimeria chalumnae	86.83	7.00e-175	607.00
IUUC-Loc-052697	Lepisosteus oculatus	85.13	2.00e-171	595.00
IUUC-Laf-054167	Loxodonta africana	80.52	2.00e-164	572.00
IUUC-Mcc-055584	Macaca mulatta	81.23	8.00e-159	553.00
IUUC-Meu-056542	Macropus eugenii	82.65	8.00e-160	557.00
IUUC-Mga-060020	Meleagris gallopavo	81.12	1.00e-156	546.00
IUUC-Mmr-060989	Microcebus murinus	81.52	1.00e-158	553.00
IUUC-Mdo-062761	Monodelphis domestica	82.65	1.00e-159	556.00
IUUC-Mmu-063710	Mus musculus	80.94	8.00e-158	550.00
IUUC-Mpu-066573	Mustela putorius furo	81.82	1.00e-159	556.00
IUUC-Nle-070013	Nomascus leucogenys	81.50	2.00e-148	519.00
IUUC-Opr-070907	Ochotona princeps	80.06	6.00e-156	544.00
IUUC-Ont-071944	Oreochromis niloticus	92.24	0.00e+00	649.00
IUUC-Oan-073105	Ornithorhynchus anatinus	73.35	4.00e-126	444.00
IUUC-Ocu-073941	Oryctolagus cuniculus	80.94	1.00e-157	550.00
IUUC-Ola-087412	Oryzias latipes	88.08	2.00e-167	582.00
IUUC-Oga-088973	Otolemur garnettii	81.23	5.00e-158	551.00
IUUC-Oar-089916	Ovis aries	74.48	4.00e-162	565.00
IUUC-Ptr-090998	Pan troglodytes	80.94	7.00e-158	550.00
IUUC-Pan-092686	Papio anubis	81.23	9.00e-159	553.00
IUUC-Psi-093284	Pelodiscus sinensis	68.34	4.00e-110	390.00
IUUC-Pfo-097352	Poecilia formosa	91.86	0.00e+00	646.00
IUUC-Pab-098688	Pongo abelii	72.43	5.00e-132	464.00
IUUC-Pca-100205	Procavia capensis	78.07	4.00e-154	538.00
IUUC-Pva-103188	Pteropus vampyrus	80.94	3.00e-156	545.00
IUUC-Rno-105853	Rattus norvegicus	81.52	4.00e-158	551.00
IUUC-Sha-107237	Sarcophilus harrisii	82.65	1.00e-159	556.00
IUUC-Smo-109021	Selaginella moellendorffii	36.26	7.00e-48	184.00
IUUC-Sar-113103	Sorex araneus	76.54	3.00e-145	508.00
IUUC-Ssc-115955	Sus scrofa	81.52	6.00e-151	527.00
IUUC-Tgu-116894	Taeniopygia guttata	80.94	7.00e-157	546.00
IUUC-Tsy-118879	Tarsius syrichta	81.23	2.00e-157	548.00
IUUC-Tni-119866	Tetraodon nigroviridis	87.50	0.00e+00	646.00
IUUC-Tbe-127367	Tupaia belangeri	77.70	2.00e-64	240.00
IUUC-Ttr-128773	Tursiops truncatus	78.30	3.00e-151	528.00
IUUC-Vpa-130402	Vicugna pacos	84.38	4.00e-101	362.00
IUUC-Xtr-132658	Xenopus tropicalis	80.17	1.00e-156	546.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence