iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Gac-042490

Ensembl Protein ID

ENSGACP00000018983.1

UniProt Accession

G3PN00; G3PN00_GASAC

Protein Name

Tyrosine-protein kinase

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGACG00000014381.1	ENSGACT00000019021.1	ENSGACP00000018983.1
ENSGACG00000014381.1	ENSGACT00000019023.1	ENSGACP00000018985.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	4.00e-15	55.9	67	123

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 4    ekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           + v+ ly+yea +dd+L +kkG++++++   e+ ++W k+++ +++k+G++P n+v++++
   Q: 67   KIVISLYPYEALHDDDLGFKKGEKMKIL---EEHGEWSKAKSLTTNKEGFIPGNYVAQAD 123
           67999***********************...999**********************9986 PP

Organism

Gasterosteus aculeatus

Protein Sequence
(Fasta)

MGCMKSRLTD GLSGGVEGKT GEQTVHTDRM DFVKDPTSNR TSNCAPDNFL LPGQRFQKRE 60
EQSGVGKIVI SLYPYEALHD DDLGFKKGEK MKILEEHGEW SKAKSLTTNK EGFIPGNYVA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGCTGCA TGAAGTCCAG GCTGACAGAC GGTCTGAGCG GGGGTGTGGA GGGGAAGACC 60
GGCGAGCAGA CTGTACATAC CGACCGCATG GACTTTGTCA AAGACCCCAC CTCCAATAGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001812	Ailuropoda melanoleuca	71.51	0.00e+00	788.00
IUUC-Apl-004139	Anas platyrhynchos	70.33	0.00e+00	767.00
IUUC-Aca-004333	Anolis carolinensis	71.60	0.00e+00	789.00
IUUC-Ame-011257	Astyanax mexicanus	80.00	0.00e+00	875.00
IUUC-Bta-013257	Bos taurus	71.90	0.00e+00	789.00
IUUC-Cja-018827	Callithrix jacchus	71.21	0.00e+00	785.00
IUUC-Cfa-020816	Canis familiaris	71.32	0.00e+00	785.00
IUUC-Cpo-021423	Cavia porcellus	71.65	0.00e+00	793.00
IUUC-Csa-024244	Chlorocebus sabaeus	71.71	0.00e+00	787.00
IUUC-Dre-028518	Danio rerio	79.57	0.00e+00	857.00
IUUC-Dno-029322	Dasypus novemcinctus	72.18	0.00e+00	795.00
IUUC-Dor-030706	Dipodomys ordii	64.85	0.00e+00	696.00
IUUC-Eca-034193	Equus caballus	71.71	0.00e+00	793.00
IUUC-Fal-037273	Ficedula albicollis	70.49	0.00e+00	776.00
IUUC-Gmo-039677	Gadus morhua	79.20	0.00e+00	767.00
IUUC-Gga-040417	Gallus gallus	70.23	0.00e+00	763.00
IUUC-Ggo-045096	Gorilla gorilla	72.09	0.00e+00	791.00
IUUC-Hsa-046214	Homo sapiens	72.09	0.00e+00	791.00
IUUC-Itr-048354	Ictidomys tridecemlineatus	71.90	0.00e+00	793.00
IUUC-Lch-049991	Latimeria chalumnae	72.15	0.00e+00	771.00
IUUC-Loc-052309	Lepisosteus oculatus	79.26	0.00e+00	868.00
IUUC-Laf-053568	Loxodonta africana	72.29	0.00e+00	794.00
IUUC-Mcc-054849	Macaca mulatta	71.71	0.00e+00	787.00
IUUC-Mmr-061519	Microcebus murinus	71.12	0.00e+00	788.00
IUUC-Mdo-062090	Monodelphis domestica	68.23	0.00e+00	744.00
IUUC-Mmu-063760	Mus musculus	71.26	0.00e+00	790.00
IUUC-Mpu-065677	Mustela putorius furo	72.09	0.00e+00	795.00
IUUC-Mlu-067386	Myotis lucifugus	71.90	0.00e+00	793.00
IUUC-Nle-069742	Nomascus leucogenys	71.71	0.00e+00	788.00
IUUC-Ont-071537	Oreochromis niloticus	83.82	0.00e+00	914.00
IUUC-Oan-073193	Ornithorhynchus anatinus	70.60	0.00e+00	786.00
IUUC-Ocu-074501	Oryctolagus cuniculus	71.90	0.00e+00	792.00
IUUC-Ola-086726	Oryzias latipes	79.73	0.00e+00	868.00
IUUC-Oga-088069	Otolemur garnettii	70.74	0.00e+00	784.00
IUUC-Oar-090091	Ovis aries	72.09	0.00e+00	792.00
IUUC-Ptr-091409	Pan troglodytes	72.09	0.00e+00	791.00
IUUC-Pan-092268	Papio anubis	71.71	0.00e+00	788.00
IUUC-Psi-093685	Pelodiscus sinensis	70.41	0.00e+00	783.00
IUUC-Pfo-096217	Poecilia formosa	81.68	0.00e+00	890.00
IUUC-Pab-098601	Pongo abelii	71.90	0.00e+00	790.00
IUUC-Rno-105557	Rattus norvegicus	71.71	0.00e+00	791.00
IUUC-Sha-106643	Sarcophilus harrisii	71.24	0.00e+00	772.00
IUUC-Ssc-116317	Sus scrofa	67.50	0.00e+00	727.00
IUUC-Tgu-116865	Taeniopygia guttata	70.54	0.00e+00	778.00
IUUC-Tru-118284	Takifugu rubripes	79.96	0.00e+00	867.00
IUUC-Tsy-119440	Tarsius syrichta	69.13	0.00e+00	754.00
IUUC-Tni-120005	Tetraodon nigroviridis	81.09	0.00e+00	874.00
IUUC-Ttr-128481	Tursiops truncatus	63.30	0.00e+00	653.00
IUUC-Xtr-131907	Xenopus tropicalis	64.04	0.00e+00	679.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence