iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mcc-054705

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

JSUE03018153

Gene Name

TRIM13

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000010898.3	ENSMMUT00000015255.3	ENSMMUP00000014297.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	4.60e-08	34.6	13	61

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkw....pglknssskefrCPlCr 46
           C+iC++ f+d p+vlpC H f+++Cl+ +    +  +      f+CP+Cr
   Q: 13   CPICCSLFDD-PRVLPCSHNFCKKCLEGIlegsVRNSLWRPAPFKCPTCR 61
           ********99.**************97776666666666999999****8 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MDVMELLEED LTCPICCSLF DDPRVLPCSH NFCKKCLEGI LEGSVRNSLW RPAPFKCPTC 60
RKETSATGIN SLQVNYSLKG IVEKYNKIKI SPKMPVCKGH LGQPLNIFCL TDMQLICGIC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTGCACGGCA GCTTAACTGG GAGACTTTCT TCCCGGGCGG CCCCACCCAG GACGGCGCCG 60
CTTCAGTCGA GCCCACCGTC TGGGCGAACA GCGTCCACTT CCCGGAGCCG CGGCCCAGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR027370--Znf-RING_LisH
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00643--zf-B_box
PF13445--zf-RING_UBOX

SMART

SM00336--BBOX
SM00184--RING

Gene Ontology

GO:0005789--C:endoplasmic reticulum membrane
GO:0016021--C:integral component of membrane
GO:0097038--C:perinuclear endoplasmic reticulum
GO:0004871--F:signal transducer activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:1902187--P:negative regulation of viral release from host cell
GO:0032897--P:negative regulation of viral transcription
GO:0010942--P:positive regulation of cell death
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0016239--P:positive regulation of macroautophagy
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0051865--P:protein autoubiquitination
GO:0010332--P:response to gamma radiation
GO:0030433--P:ubiquitin-dependent ERAD pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002269	Ailuropoda melanoleuca	91.93	0.00e+00	736.00
IUUC-Apl-004168	Anas platyrhynchos	76.04	0.00e+00	631.00
IUUC-Aca-004395	Anolis carolinensis	69.02	6.00e-164	570.00
IUUC-Ame-011325	Astyanax mexicanus	46.13	1.00e-67	250.00
IUUC-Bta-012613	Bos taurus	91.40	0.00e+00	731.00
IUUC-Cja-018856	Callithrix jacchus	96.09	0.00e+00	785.00
IUUC-Cfa-021019	Canis familiaris	91.69	0.00e+00	729.00
IUUC-Cpo-021845	Cavia porcellus	91.15	0.00e+00	723.00
IUUC-Csa-023380	Chlorocebus sabaeus	98.53	0.00e+00	767.00
IUUC-Cho-024733	Choloepus hoffmanni	81.45	2.00e-87	315.00
IUUC-Dre-028675	Danio rerio	60.13	1.00e-109	389.00
IUUC-Dno-030018	Dasypus novemcinctus	89.46	0.00e+00	715.00
IUUC-Dor-030599	Dipodomys ordii	89.85	2.00e-125	441.00
IUUC-Dse-031522	Dothistroma septosporum	35.53	2.00e-06	46.60
IUUC-Ete-033134	Echinops telfairi	87.32	0.00e+00	721.00
IUUC-Eca-033931	Equus caballus	92.91	0.00e+00	734.00
IUUC-Eeu-034903	Erinaceus europaeus	89.98	0.00e+00	717.00
IUUC-Fca-035642	Felis catus	91.65	0.00e+00	728.00
IUUC-Fal-037108	Ficedula albicollis	76.47	0.00e+00	635.00
IUUC-Gga-040903	Gallus gallus	74.75	3.00e-176	611.00
IUUC-Ggo-044635	Gorilla gorilla	96.82	0.00e+00	763.00
IUUC-Hsa-046345	Homo sapiens	96.83	0.00e+00	766.00
IUUC-Itr-048220	Ictidomys tridecemlineatus	90.98	0.00e+00	706.00
IUUC-Lch-050599	Latimeria chalumnae	61.04	3.00e-137	481.00
IUUC-Loc-052378	Lepisosteus oculatus	64.38	8.00e-119	419.00
IUUC-Laf-053332	Loxodonta africana	90.93	0.00e+00	723.00
IUUC-Meu-056825	Macropus eugenii	83.41	0.00e+00	685.00
IUUC-Mga-059528	Meleagris gallopavo	75.00	2.00e-180	624.00
IUUC-Mmr-060688	Microcebus murinus	93.15	0.00e+00	738.00
IUUC-Mdo-061882	Monodelphis domestica	83.86	0.00e+00	696.00
IUUC-Mmu-064352	Mus musculus	87.71	0.00e+00	727.00
IUUC-Mpu-066712	Mustela putorius furo	91.56	0.00e+00	674.00
IUUC-Mlu-068093	Myotis lucifugus	91.63	0.00e+00	726.00
IUUC-Nle-069310	Nomascus leucogenys	96.56	0.00e+00	756.00
IUUC-Ont-071759	Oreochromis niloticus	59.28	2.00e-110	392.00
IUUC-Oan-073673	Ornithorhynchus anatinus	79.76	0.00e+00	667.00
IUUC-Ocu-074192	Oryctolagus cuniculus	90.95	0.00e+00	732.00
IUUC-Ola-087424	Oryzias latipes	58.77	1.00e-108	386.00
IUUC-Oga-088808	Otolemur garnettii	92.87	0.00e+00	739.00
IUUC-Oar-089553	Ovis aries	91.44	0.00e+00	734.00
IUUC-Ptr-090518	Pan troglodytes	96.58	0.00e+00	759.00
IUUC-Pan-092781	Papio anubis	99.75	0.00e+00	776.00
IUUC-Psi-093914	Pelodiscus sinensis	75.79	5.00e-180	623.00
IUUC-Pfo-096346	Poecilia formosa	56.70	6.00e-108	384.00
IUUC-Pca-100914	Procavia capensis	88.54	0.00e+00	735.00
IUUC-Pva-102728	Pteropus vampyrus	91.93	0.00e+00	731.00
IUUC-Rno-105922	Rattus norvegicus	87.71	0.00e+00	681.00
IUUC-Sha-107124	Sarcophilus harrisii	83.86	0.00e+00	699.00
IUUC-Sja-107830	Schizosaccharomyces japonicus	36.05	6.00e-07	48.90
IUUC-Sar-113607	Sorex araneus	88.26	0.00e+00	698.00
IUUC-Ssc-116355	Sus scrofa	92.38	0.00e+00	737.00
IUUC-Tgu-116476	Taeniopygia guttata	76.72	0.00e+00	632.00
IUUC-Tru-118737	Takifugu rubripes	60.26	6.00e-113	400.00
IUUC-Tsy-118908	Tarsius syrichta	92.67	0.00e+00	737.00
IUUC-Tbe-127258	Tupaia belangeri	94.38	0.00e+00	752.00
IUUC-Vpa-130138	Vicugna pacos	91.93	0.00e+00	738.00
IUUC-Xtr-132100	Xenopus tropicalis	58.54	2.00e-134	472.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence