iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ssc-115288

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

CT990641

Gene Name

OTUB2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSSCG00000002469.2	ENSSSCT00000002741.2	ENSSSCP00000002672.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/OTU	8.00e-47	159.4	41	230

Active Site

Position(s)	Description	Evidence
48	N/A	{ECO:0000256\|PIRSR:PIRSR013503-1}
51	Nucleophile	{ECO:0000256\|PIRSR:PIRSR013503-1}
224		{ECO:0000256\|PIRSR:PIRSR013503-1}

Domain Profile

DUB/OTU

   S: 2    lilktkgDGnCLlrAvsqs..........................................................llgvfdddslsd 32
           +i+ktkgDGnC++rA+++s                                                          ll+vf+d+s sd
   Q: 41   AIRKTKGDGNCFYRALGYSylesllgksreilkfkervlqtpndllaagfeehkfqnffnafysvvelvekdgsvssLLKVFNDQSSSD 129
           79*************************************************************************************** PP
   S: 33   alveaLreltseylqkesdffsefieekedekefcqklvepeak.geeihifaLaqiLsrpiivvdvdsleskvggillpllfpeeklk 120
            +v++Lr+lts+++++++dff++fi+e++d+ +fc+++vep+a  +++i+i+aL+q+L+++++v++vd++++    +l++++fpe++  
   Q: 130  RIVQFLRLLTSAFIRNRADFFRHFIDEEMDIRDFCTHEVEPMAMeCDHIQITALSQALNIALQVEYVDEMDT----ALNHHVFPEAA-I 213
           **********************************************************************95....***********.* PP
   S: 121  kpivLlYrsgHYdaLva 137
           ++++LlY+++HY++L+a
   Q: 214  PSVYLLYKTSHYNILYA 230
           ***************97 PP

Organism

Sus scrofa

Protein Sequence
(Fasta)

MSETPFNLIS EKCDILSILR DHPENRIYQR KIQELSKRFT AIRKTKGDGN CFYRALGYSY 60
LESLLGKSRE ILKFKERVLQ TPNDLLAAGF EEHKFQNFFN AFYSVVELVE KDGSVSSLLK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGGGGCGTGT GTCTTGCTGG GACACAGTGG AGGTCTAACC TCTGGTTTGC GGAGCGGTCG 60
GGTGTATTCT CCGCTCGCCC CCACGCCCTC GAGGCCCCCG CCGCCCAACC CAACGGCGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR003323--OTU_dom
IPR030299--OTUB2
IPR016615--Otubain
IPR019400--Peptidase_C65_otubain

PROSITE

PS50802--OTU

Pfam

PF10275--Peptidase_C65

Gene Ontology

GO:0005634--C:nucleus
GO:0019784--F:NEDD8-specific protease activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0043130--F:ubiquitin binding
GO:0035871--P:protein K11-linked deubiquitination
GO:0071108--P:protein K48-linked deubiquitination
GO:0070536--P:protein K63-linked deubiquitination

KEGG

ssc:100151873

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002059	Ailuropoda melanoleuca	96.14	2.00e-133	467.00
IUUC-Bta-012766	Bos taurus	96.57	5.00e-133	466.00
IUUC-Cja-019480	Callithrix jacchus	93.97	8.00e-130	455.00
IUUC-Cfa-021106	Canis familiaris	96.57	4.00e-134	469.00
IUUC-Cpo-022187	Cavia porcellus	96.98	2.00e-133	467.00
IUUC-Csa-023493	Chlorocebus sabaeus	95.26	9.00e-131	458.00
IUUC-Cho-024411	Choloepus hoffmanni	76.59	1.00e-85	308.00
IUUC-Dno-029346	Dasypus novemcinctus	97.01	1.00e-134	471.00
IUUC-Dor-031012	Dipodomys ordii	97.41	1.00e-134	471.00
IUUC-Ete-032266	Echinops telfairi	86.70	1.00e-119	421.00
IUUC-Eca-033356	Equus caballus	97.85	8.00e-135	472.00
IUUC-Eeu-034775	Erinaceus europaeus	97.00	3.00e-134	469.00
IUUC-Fca-035363	Felis catus	95.26	3.00e-131	460.00
IUUC-Ggo-045023	Gorilla gorilla	94.85	5.00e-131	459.00
IUUC-Hsa-046984	Homo sapiens	95.28	1.00e-131	461.00
IUUC-Itr-048012	Ictidomys tridecemlineatus	96.14	1.00e-133	468.00
IUUC-Lch-050514	Latimeria chalumnae	61.33	2.00e-83	301.00
IUUC-Loc-052003	Lepisosteus oculatus	50.45	1.00e-64	239.00
IUUC-Laf-054382	Loxodonta africana	95.28	3.00e-132	463.00
IUUC-Mcc-055516	Macaca mulatta	95.26	6.00e-131	459.00
IUUC-Meu-056038	Macropus eugenii	87.83	4.00e-99	353.00
IUUC-Mmr-060918	Microcebus murinus	97.00	3.00e-134	470.00
IUUC-Mdo-062638	Monodelphis domestica	89.70	9.00e-125	438.00
IUUC-Mmu-063973	Mus musculus	96.98	3.00e-133	467.00
IUUC-Mpu-066013	Mustela putorius furo	96.14	8.00e-134	468.00
IUUC-Mlu-067509	Myotis lucifugus	94.42	4.00e-130	456.00
IUUC-Nle-069673	Nomascus leucogenys	95.28	1.00e-131	461.00
IUUC-Opr-070761	Ochotona princeps	88.55	2.00e-82	296.00
IUUC-Oan-072922	Ornithorhynchus anatinus	81.66	1.00e-111	395.00
IUUC-Ocu-074643	Oryctolagus cuniculus	95.71	1.00e-132	465.00
IUUC-Oni-082026	Oryza nivara	29.95	2.00e-15	77.00
IUUC-Oru-084761	Oryza rufipogon	29.95	2.00e-15	77.00
IUUC-Ola-086603	Oryzias latipes	45.37	1.00e-51	196.00
IUUC-Oga-088936	Otolemur garnettii	95.69	5.00e-132	462.00
IUUC-Oar-089460	Ovis aries	96.98	2.00e-132	464.00
IUUC-Ptr-090805	Pan troglodytes	94.85	4.00e-131	459.00
IUUC-Pan-091969	Papio anubis	95.28	1.00e-131	461.00
IUUC-Pab-098476	Pongo abelii	94.83	3.00e-130	456.00
IUUC-Pca-100252	Procavia capensis	94.06	2.00e-55	208.00
IUUC-Pva-102204	Pteropus vampyrus	95.28	1.00e-132	464.00
IUUC-Pgr-103552	Puccinia graminis	75.00	2.40e-02	31.20
IUUC-Rno-105062	Rattus norvegicus	96.14	2.00e-133	467.00
IUUC-Sha-106968	Sarcophilus harrisii	89.52	1.00e-122	431.00
IUUC-Sar-113295	Sorex araneus	97.00	3.00e-132	463.00
IUUC-Tni-120440	Tetraodon nigroviridis	39.57	1.00e-42	166.00
IUUC-Tbe-127717	Tupaia belangeri	96.62	2.00e-79	286.00
IUUC-Ttr-128221	Tursiops truncatus	78.63	2.00e-103	367.00
IUUC-Uma-129443	Ustilago maydis	33.17	4.00e-24	105.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence