iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMUSG00000003283.14	ENSMUST00000003370.13	ENSMUSP00000003370.7
ENSMUSG00000003283.14	ENSMUST00000191431.7	ENSMUSP00000139988.2

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	GXD
DNA & RNA Element
AREsite	microRNA	TRANSFAC	RepTar
RAID2
Protein-protein Interaction
HINT
Post-translational Modifications (PTMs)
PHOSIDA
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	8.50e-16	58.8	78	135

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 3    kekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           +  v +lydyea + ++L+++kGd++ v+   e+ ++W+k+ + +++k+G +P+n+v++++
   Q: 78   DTIVVALYDYEAIHREDLSFQKGDQMVVL---EEAGEWWKARSLATKKEGYIPSNYVARVN 135
           56899************************...999************************97 PP

Organism

Mus musculus

Protein Sequence
(Fasta)

LGGRSSCEDP GCPRSEGRAP RMGCVKSRFL RDGSKASKTE PSANQKGPVY VPDPTSSSKL 60
GPNNSNSMPP GFVEGSEDTI VVALYDYEAI HREDLSFQKG DQMVVLEEAG EWWKARSLAT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATCACCCAGG GTGCGGCTAA GGCGCCCAGA TGGCCAGTGA GCGCCACTGG GTTGCGGCTC 60
CCAGCTTGCA CTCCCCGCGG CGGCTCTCAG ACGGGTGGGA GGGGACCAAA GTCGCCCGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0005886--C:plasma membrane
GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000140	Aegilops tauschii	31.01	7.00e-22	99.80
IUUC-Aml-001284	Ailuropoda melanoleuca	87.83	0.00e+00	969.00
IUUC-Apl-003285	Anas platyrhynchos	77.54	0.00e+00	815.00
IUUC-Aca-004724	Anolis carolinensis	76.62	0.00e+00	791.00
IUUC-Ame-011954	Astyanax mexicanus	74.70	0.00e+00	765.00
IUUC-Bta-013060	Bos taurus	90.08	0.00e+00	996.00
IUUC-Cja-019817	Callithrix jacchus	89.72	0.00e+00	931.00
IUUC-Cfa-020511	Canis familiaris	88.74	0.00e+00	983.00
IUUC-Cpo-022538	Cavia porcellus	90.10	0.00e+00	954.00
IUUC-Csa-024143	Chlorocebus sabaeus	90.10	0.00e+00	946.00
IUUC-Dre-028157	Danio rerio	74.40	0.00e+00	786.00
IUUC-Dno-029761	Dasypus novemcinctus	88.49	0.00e+00	936.00
IUUC-Eca-034090	Equus caballus	87.40	0.00e+00	963.00
IUUC-Fca-035937	Felis catus	86.07	0.00e+00	928.00
IUUC-Fal-036624	Ficedula albicollis	77.65	0.00e+00	809.00
IUUC-Gmo-039009	Gadus morhua	72.37	0.00e+00	759.00
IUUC-Gga-040296	Gallus gallus	75.45	0.00e+00	790.00
IUUC-Gac-042362	Gasterosteus aculeatus	72.58	0.00e+00	772.00
IUUC-Ggo-044570	Gorilla gorilla	89.54	0.00e+00	976.00
IUUC-Hsa-046378	Homo sapiens	89.73	0.00e+00	984.00
IUUC-Hvu-047855	Hordeum vulgare	31.01	3.00e-22	100.00
IUUC-Itr-048695	Ictidomys tridecemlineatus	89.71	0.00e+00	975.00
IUUC-Loc-052904	Lepisosteus oculatus	77.17	0.00e+00	823.00
IUUC-Laf-053654	Loxodonta africana	89.29	0.00e+00	952.00
IUUC-Mcc-055317	Macaca mulatta	90.48	0.00e+00	953.00
IUUC-Mga-060194	Meleagris gallopavo	81.07	0.00e+00	773.00
IUUC-Mmr-061510	Microcebus murinus	89.09	0.00e+00	945.00
IUUC-Mdo-062035	Monodelphis domestica	82.97	0.00e+00	889.00
IUUC-Mpu-066874	Mustela putorius furo	88.69	0.00e+00	946.00
IUUC-Mlu-068202	Myotis lucifugus	83.82	0.00e+00	895.00
IUUC-Nle-069222	Nomascus leucogenys	90.08	0.00e+00	943.00
IUUC-Opr-070705	Ochotona princeps	87.26	0.00e+00	971.00
IUUC-Ont-072347	Oreochromis niloticus	80.58	0.00e+00	760.00
IUUC-Ocu-074490	Oryctolagus cuniculus	88.07	0.00e+00	937.00
IUUC-Ola-086521	Oryzias latipes	78.19	0.00e+00	767.00
IUUC-Oga-088153	Otolemur garnettii	88.51	0.00e+00	937.00
IUUC-Oar-090184	Ovis aries	88.82	0.00e+00	962.00
IUUC-Ptr-090505	Pan troglodytes	85.93	0.00e+00	924.00
IUUC-Pan-092260	Papio anubis	90.28	0.00e+00	952.00
IUUC-Pma-094311	Petromyzon marinus	71.67	0.00e+00	735.00
IUUC-Pfo-096566	Poecilia formosa	74.75	0.00e+00	797.00
IUUC-Pva-103021	Pteropus vampyrus	89.88	0.00e+00	952.00
IUUC-Rno-105309	Rattus norvegicus	97.42	0.00e+00	1025.00
IUUC-Sha-107099	Sarcophilus harrisii	81.89	0.00e+00	878.00
IUUC-Tgu-116912	Taeniopygia guttata	76.77	0.00e+00	798.00
IUUC-Tru-118449	Takifugu rubripes	79.33	0.00e+00	751.00
IUUC-Tae-123706	Triticum aestivum	31.40	1.00e-22	101.00
IUUC-Tur-126022	Triticum urartu	31.40	2.00e-22	101.00
IUUC-Tbe-128144	Tupaia belangeri	85.78	0.00e+00	794.00
IUUC-Xma-133902	Xiphophorus maculatus	74.26	0.00e+00	787.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence