iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ola-086521

Ensembl Protein ID

ENSORLP00000002943.1

UniProt Accession

H2LAN1; H2LAN1_ORYLA

Genbank Protein ID

ENSORLP00000002943

Protein Name

Tyrosine-protein kinase

Genbank Nucleotide ID

BAAF04064729

Gene Name

hck

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSORLG00000002368.1	ENSORLT00000002944.1	ENSORLP00000002943.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	2.60e-15	56.4	10	62

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 6    vqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
            ++lydyea ++++L +kkGd ++++   e++++W+k+++  +g++G++P+n+v+k
   Q: 10   AIALYDYEAIHEGDLGFKKGDRLKIL---EESGEWWKAKSISSGQEGFIPSNYVAK 62
           689***********************...99***********************86 PP

Organism

Oryzias latipes

Protein Sequence
(Fasta)

FLTALGESVA IALYDYEAIH EGDLGFKKGD RLKILEESGE WWKAKSISSG QEGFIPSNYV 60
AKDTLETEDW FFKGVSRKDA ERQLLASGNK TGSFMIRDSE TTRGSYSLSV RDHDPQAGDT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTTTTGACCG CTTTAGGGGA GAGTGTTGCC ATCGCATTGT ATGACTATGA AGCCATTCAC 60
GAGGGAGACC TGGGCTTCAA AAAGGGCGAC AGGCTTAAAA TTTTGGAAGA GTGAGTGGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001284	Ailuropoda melanoleuca	81.39	0.00e+00	772.00
IUUC-Apl-003285	Anas platyrhynchos	80.79	0.00e+00	768.00
IUUC-Aca-004724	Anolis carolinensis	82.64	0.00e+00	769.00
IUUC-Ame-011954	Astyanax mexicanus	89.51	0.00e+00	825.00
IUUC-Bta-013060	Bos taurus	80.49	0.00e+00	771.00
IUUC-Cja-019817	Callithrix jacchus	81.39	0.00e+00	775.00
IUUC-Cfa-020511	Canis familiaris	81.39	0.00e+00	775.00
IUUC-Cpo-022538	Cavia porcellus	79.64	0.00e+00	762.00
IUUC-Csa-024143	Chlorocebus sabaeus	81.84	0.00e+00	777.00
IUUC-Dre-028157	Danio rerio	91.35	0.00e+00	870.00
IUUC-Dno-029761	Dasypus novemcinctus	79.91	0.00e+00	774.00
IUUC-Eca-034090	Equus caballus	79.69	0.00e+00	752.00
IUUC-Fca-035937	Felis catus	80.18	0.00e+00	743.00
IUUC-Fal-036624	Ficedula albicollis	79.38	0.00e+00	769.00
IUUC-Gmo-039009	Gadus morhua	85.46	0.00e+00	817.00
IUUC-Gga-040296	Gallus gallus	79.24	0.00e+00	760.00
IUUC-Gac-042362	Gasterosteus aculeatus	92.39	0.00e+00	874.00
IUUC-Ggo-044570	Gorilla gorilla	81.39	0.00e+00	779.00
IUUC-Hsa-046378	Homo sapiens	81.61	0.00e+00	781.00
IUUC-Itr-048695	Ictidomys tridecemlineatus	79.46	0.00e+00	767.00
IUUC-Loc-052904	Lepisosteus oculatus	88.64	0.00e+00	850.00
IUUC-Laf-053654	Loxodonta africana	80.94	0.00e+00	773.00
IUUC-Mcc-055317	Macaca mulatta	82.06	0.00e+00	782.00
IUUC-Mga-060194	Meleagris gallopavo	76.56	0.00e+00	728.00
IUUC-Mmr-061510	Microcebus murinus	80.49	0.00e+00	771.00
IUUC-Mdo-062035	Monodelphis domestica	79.82	0.00e+00	761.00
IUUC-Mmu-064037	Mus musculus	78.19	0.00e+00	767.00
IUUC-Mpu-066874	Mustela putorius furo	81.39	0.00e+00	770.00
IUUC-Mlu-068202	Myotis lucifugus	78.35	0.00e+00	747.00
IUUC-Nle-069222	Nomascus leucogenys	82.06	0.00e+00	782.00
IUUC-Opr-070705	Ochotona princeps	80.04	0.00e+00	767.00
IUUC-Ont-072347	Oreochromis niloticus	92.62	0.00e+00	850.00
IUUC-Ocu-074490	Oryctolagus cuniculus	80.49	0.00e+00	772.00
IUUC-Oga-088153	Otolemur garnettii	81.47	0.00e+00	780.00
IUUC-Oar-090184	Ovis aries	79.51	0.00e+00	762.00
IUUC-Ptr-090505	Pan troglodytes	77.35	0.00e+00	728.00
IUUC-Pan-092260	Papio anubis	82.06	0.00e+00	783.00
IUUC-Pma-094311	Petromyzon marinus	73.03	0.00e+00	706.00
IUUC-Pfo-096566	Poecilia formosa	93.08	0.00e+00	886.00
IUUC-Pva-103021	Pteropus vampyrus	82.06	0.00e+00	776.00
IUUC-Rno-105309	Rattus norvegicus	79.24	0.00e+00	768.00
IUUC-Sha-107099	Sarcophilus harrisii	79.37	0.00e+00	759.00
IUUC-Tgu-116912	Taeniopygia guttata	80.67	0.00e+00	770.00
IUUC-Tru-118449	Takifugu rubripes	89.71	0.00e+00	837.00
IUUC-Tbe-128144	Tupaia belangeri	72.87	0.00e+00	682.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence