iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	GXD
DNA & RNA Element
AREsite	miRTarBase	microRNA	TRANSFAC
miRNAMap	RAID2
Post-translational Modifications (PTMs)
dbPAF	PhosphositePlus	PHOSIDA
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	37.04	3.30e-02	30.00	IUUC-Ots-000003

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Mus musculus

Functional Description
(View)

Suppresses neurite outgrowth.

Protein Sequence
(Fasta)

MHVCCPPVTL EQDLHRKMHS WMLQTLAFAV TSLVLSCAET IDYYGEICDN ACPCEEKDGI 60
LTVSCENRGI ISLSEISPPR FPIYHLLLSG NLLSRLYPNE FVNYTGASIL HLGSNVIQDI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATAGAGCGTC CAAGCTGCCA GGACATGCCA CAGGCATAGA GCAACGCTGC TCCTACCCCC 60
CTTGGACCCC TCAAAGGATG TCGGAGATAA AGAGTTGCAA ATAATGAGGA TCGTGCGCCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0325--Glycoprotein
KW-0433--Leucine-rich repeat
KW-0472--Membrane
KW-1185--Reference proteome
KW-0677--Repeat
KW-0732--Signal
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR000483--Cys-rich_flank_reg_C
IPR032675--L_dom-like
IPR001611--Leu-rich_rpt
IPR003591--Leu-rich_rpt_typical-subtyp

PROSITE

Pfam

SMART

SM00369--LRR_TYP
SM00082--LRRCT

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0043235--C:receptor complex
GO:0030534--P:adult behavior
GO:0007409--P:axonogenesis
GO:0072358--P:cardiovascular system development
GO:0007268--P:chemical synaptic transmission
GO:0048813--P:dendrite morphogenesis
GO:0007625--P:grooming behavior
GO:0051965--P:positive regulation of synapse assembly
GO:0009410--P:response to xenobiotic stimulus
GO:0043588--P:skin development
GO:0021756--P:striatum development

KEGG

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Csa-023577	Chlorocebus sabaeus	96.56	0.00e+00	1520.00
IUUC-Ete-033058	Echinops telfairi	89.42	0.00e+00	1415.00
IUUC-Eeu-034992	Erinaceus europaeus	90.62	0.00e+00	1410.00
IUUC-Itr-049036	Ictidomys tridecemlineatus	96.76	0.00e+00	1511.00
IUUC-Laf-053744	Loxodonta africana	88.60	0.00e+00	1381.00
IUUC-Mcc-054736	Macaca mulatta	96.66	0.00e+00	1520.00
IUUC-Meu-056385	Macropus eugenii	89.74	0.00e+00	1433.00
IUUC-Mmr-061392	Microcebus murinus	96.25	0.00e+00	1531.00
IUUC-Nle-069805	Nomascus leucogenys	96.66	0.00e+00	1525.00
IUUC-Oan-072964	Ornithorhynchus anatinus	87.45	0.00e+00	1408.00
IUUC-Ocu-074432	Oryctolagus cuniculus	92.10	0.00e+00	944.00
IUUC-Oga-088981	Otolemur garnettii	94.37	0.00e+00	1520.00
IUUC-Pan-092663	Papio anubis	94.15	0.00e+00	1552.00
IUUC-Pab-098234	Pongo abelii	96.25	0.00e+00	1537.00
IUUC-Pca-101050	Procavia capensis	90.73	0.00e+00	1087.00
IUUC-Rno-105043	Rattus norvegicus	98.75	0.00e+00	1541.00
IUUC-Sha-106791	Sarcophilus harrisii	90.24	0.00e+00	1452.00
IUUC-Sar-112932	Sorex araneus	93.97	0.00e+00	1080.00
IUUC-Ssc-115557	Sus scrofa	95.33	0.00e+00	1496.00

Created Date

25-Jun-2017

Functional Description