iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tni-119968

Ensembl Protein ID

ENSTNIP00000017955.1

UniProt Accession

H3DBR2; H3DBR2_TETNG

Protein Name

Protein kinase C

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTNIG00000014911.1	ENSTNIT00000018179.1	ENSTNIP00000017955.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
ULD/UDP/UFD/PB1	7.60e-21	74.3	18	99

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

ULD/UDP/UFD/PB1

   S: 1    tvrvkvsykgeirsfaldlekpgkfedLlkavrtltelkn.sevalkYeDedGDlvtlksDedldkavslla.skksllrlliq 82
           +vrvk++ykg+i  + +++e+++++e L+ +vr++++++n + +++k+ De+GD +t++s+ +l++a++l++ +k+s l ++++
   Q: 18   QVRVKAYYKGDI--MITHFEPSISYEGLYGEVRDMCSMDNdQLFTMKWIDEEGDPCTVSSQLELEEALRLYElNKDSELIIHVF 99
           69**********..88******************************************************************98 PP

Organism

Tetraodon nigroviridis

Protein Sequence
(Fasta)

MPTLRDSTMS HPGENSHQVR VKAYYKGDIM ITHFEPSISY EGLYGEVRDM CSMDNDQLFT 60
MKWIDEEGDP CTVSSQLELE EALRLYELNK DSELIIHVFP CVPENPGMPC PGEDISQSEI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCCGACGT TGCGGGACAG CACCATGTCC CACCCCGGCG AGAATTCCCA CCAAGTTCGG 60
GTTAAAGCTT ATTACAAAGG GTAAGTAATC ACCGTCTGAA TTTATATGTT GAGACAATTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0479--Metal-binding
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR000961--AGC-kinase_C
IPR020454--DAG/PE-bd
IPR011009--Kinase-like_dom
IPR000270--PB1_dom
IPR002219--PE/DAG-bd
IPR012233--PKC
IPR017892--Pkinase_C
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR008271--Ser/Thr_kinase_AS

PROSITE

PS51285--AGC_KINASE_CTER
PS51745--PB1
PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
PS50081--ZF_DAG_PE_2

Pfam

PF00130--C1_1
PF00564--PB1
PF00069--Pkinase
PF00433--Pkinase_C

PRINTS

PR00008--DAGPEDOMAIN

SMART

SM00109--C1
SM00666--PB1
SM00133--S_TK_X
SM00220--S_TKc

Gene Ontology

GO:0005622--C:intracellular
GO:0031226--C:intrinsic component of plasma membrane
GO:0005915--C:zonula adherens
GO:0005524--F:ATP binding
GO:0046872--F:metal ion binding
GO:0004697--F:protein kinase C activity
GO:0034334--P:adherens junction maintenance
GO:0045217--P:cell-cell junction maintenance
GO:0007502--P:digestive tract mesoderm development
GO:0048546--P:digestive tract morphogenesis
GO:0021744--P:dorsal motor nucleus of vagus nerve development
GO:0035050--P:embryonic heart tube development
GO:0000132--P:establishment of mitotic spindle orientation
GO:0016332--P:establishment or maintenance of polarity of embryonic epithelium
GO:0035556--P:intracellular signal transduction
GO:0045199--P:maintenance of epithelial cell apical/basal polarity
GO:0008078--P:mesodermal cell migration
GO:0001738--P:morphogenesis of a polarized epithelium
GO:0001841--P:neural tube formation
GO:0007405--P:neuroblast proliferation
GO:0007097--P:nuclear migration
GO:0042476--P:odontogenesis
GO:0035845--P:photoreceptor cell outer segment organization
GO:0035778--P:pronephric nephron tubule epithelial cell differentiation
GO:0060042--P:retina morphogenesis in camera-type eye
GO:0021591--P:ventricular system development

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001764	Ailuropoda melanoleuca	86.41	0.00e+00	890.00
IUUC-Apl-003711	Anas platyrhynchos	87.24	0.00e+00	961.00
IUUC-Aca-005142	Anolis carolinensis	87.14	0.00e+00	981.00
IUUC-Ame-010977	Astyanax mexicanus	87.67	0.00e+00	993.00
IUUC-Bta-013414	Bos taurus	85.71	0.00e+00	1010.00
IUUC-Bol-015169	Brassica oleracea	34.51	4.00e-50	193.00
IUUC-Cel-018340	Caenorhabditis elegans	56.84	0.00e+00	674.00
IUUC-Cja-019802	Callithrix jacchus	86.63	0.00e+00	968.00
IUUC-Cfa-021236	Canis familiaris	85.79	0.00e+00	993.00
IUUC-Cpo-022127	Cavia porcellus	85.00	0.00e+00	944.00
IUUC-Csa-023332	Chlorocebus sabaeus	86.26	0.00e+00	823.00
IUUC-Cho-025054	Choloepus hoffmanni	91.87	2.00e-60	226.00
IUUC-Cin-025740	Ciona intestinalis	58.21	0.00e+00	689.00
IUUC-Csv-026145	Ciona savignyi	74.62	2.00e-172	598.00
IUUC-Dre-028444	Danio rerio	90.64	0.00e+00	1021.00
IUUC-Dno-029228	Dasypus novemcinctus	97.10	9.00e-178	615.00
IUUC-Dme-031630	Drosophila melanogaster	65.94	0.00e+00	765.00
IUUC-Ete-032633	Echinops telfairi	66.00	3.00e-164	571.00
IUUC-Eca-033572	Equus caballus	86.78	0.00e+00	972.00
IUUC-Eeu-035110	Erinaceus europaeus	85.98	0.00e+00	1001.00
IUUC-Fca-035559	Felis catus	85.55	0.00e+00	1011.00
IUUC-Fal-036953	Ficedula albicollis	87.41	0.00e+00	964.00
IUUC-Gmo-039334	Gadus morhua	91.81	0.00e+00	1070.00
IUUC-Gga-040223	Gallus gallus	85.57	0.00e+00	994.00
IUUC-Gac-042113	Gasterosteus aculeatus	92.81	0.00e+00	1085.00
IUUC-Ggo-044520	Gorilla gorilla	82.03	0.00e+00	924.00
IUUC-Hsa-046991	Homo sapiens	85.55	0.00e+00	1009.00
IUUC-Lch-050263	Latimeria chalumnae	85.64	0.00e+00	995.00
IUUC-Loc-052221	Lepisosteus oculatus	89.46	0.00e+00	1008.00
IUUC-Laf-053591	Loxodonta africana	85.88	0.00e+00	1010.00
IUUC-Mcc-055118	Macaca mulatta	85.79	0.00e+00	1002.00
IUUC-Mga-059886	Meleagris gallopavo	87.41	0.00e+00	962.00
IUUC-Mmr-060926	Microcebus murinus	85.55	0.00e+00	1008.00
IUUC-Mdo-062698	Monodelphis domestica	83.31	0.00e+00	976.00
IUUC-Mmu-063689	Mus musculus	85.86	0.00e+00	1004.00
IUUC-Mpu-066630	Mustela putorius furo	86.61	0.00e+00	998.00
IUUC-Mlu-067416	Myotis lucifugus	83.17	0.00e+00	954.00
IUUC-Nle-069811	Nomascus leucogenys	85.55	0.00e+00	1010.00
IUUC-Opr-070466	Ochotona princeps	78.63	0.00e+00	668.00
IUUC-Ont-072278	Oreochromis niloticus	90.74	0.00e+00	1002.00
IUUC-Oan-073651	Ornithorhynchus anatinus	95.30	0.00e+00	702.00
IUUC-Ocu-074383	Oryctolagus cuniculus	85.88	0.00e+00	1010.00
IUUC-Ola-087283	Oryzias latipes	85.90	0.00e+00	840.00
IUUC-Oga-088337	Otolemur garnettii	78.99	0.00e+00	902.00
IUUC-Oar-089954	Ovis aries	86.81	0.00e+00	976.00
IUUC-Ptr-091673	Pan troglodytes	85.55	0.00e+00	1009.00
IUUC-Pan-092494	Papio anubis	85.55	0.00e+00	1007.00
IUUC-Psi-094044	Pelodiscus sinensis	84.19	0.00e+00	991.00
IUUC-Pfo-096661	Poecilia formosa	90.32	0.00e+00	1031.00
IUUC-Pab-097659	Pongo abelii	85.22	0.00e+00	1003.00
IUUC-Pca-101107	Procavia capensis	88.40	0.00e+00	705.00
IUUC-Rno-105790	Rattus norvegicus	85.71	0.00e+00	1006.00
IUUC-Sha-106895	Sarcophilus harrisii	86.70	0.00e+00	952.00
IUUC-Sar-113513	Sorex araneus	79.64	2.00e-143	502.00
IUUC-Ssc-115835	Sus scrofa	86.17	0.00e+00	891.00
IUUC-Tgu-116874	Taeniopygia guttata	85.27	0.00e+00	993.00
IUUC-Tru-117823	Takifugu rubripes	96.13	0.00e+00	1094.00
IUUC-Tsy-119154	Tarsius syrichta	86.78	0.00e+00	972.00
IUUC-Tbe-127238	Tupaia belangeri	69.03	0.00e+00	653.00
IUUC-Ttr-129208	Tursiops truncatus	85.41	0.00e+00	1008.00
IUUC-Vpa-130363	Vicugna pacos	77.50	0.00e+00	877.00
IUUC-Xtr-132652	Xenopus tropicalis	83.17	0.00e+00	964.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence