iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Fca-036287

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AANG02155036

Gene Name

TRIM59

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFCAG00000019137.1	ENSFCAT00000019352.1	ENSFCAP00000015540.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	3.90e-06	26.9	6	89
E3 activity/RING/RING	1.40e-09	38.3	10	60

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 4    eeflCpIslelMrdPvvlpsGitydrssIekwlasggk...........tcPvtrqpl.....teedlvPnltlrrliqawcee 71
           +e+ CpI + +++dP vlp+ +t+ r+++e  l+ +g+           +cP +r+ +       e+l  n +lr++i+++ +e
   Q: 6    DELTCPICYSIFEDPRVLPCSHTFCRNCLENVLQASGNfyiwrplriplKCPNCRSIIeiapsGIESLPVNFALRAIIEKYQQE 89
           7899*****************************9999999*********99999987744322346677788999999998776 PP

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefr..........CPlCr 46
           C+iC++ f+d p+vlpC H+f+++Cl+++     ++s++f+          CP Cr
   Q: 10   CPICYSIFED-PRVLPCSHTFCRNCLENV----LQASGNFYiwrplriplkCPNCR 60
           **********.***************999....667777766667777777****8 PP

Organism

Felis catus

Protein Sequence
(Fasta)

MHNFEDELTC PICYSIFEDP RVLPCSHTFC RNCLENVLQA SGNFYIWRPL RIPLKCPNCR 60
SIIEIAPSGI ESLPVNFALR AIIEKYQQED HPDIVTCPEH YRQPLNVYCL LDKKLVCGHC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCACAATT TTGAGGACGA GTTAACATGT CCCATTTGTT ACAGTATTTT TGAAGATCCT 60
CGTGTACTAC CATGCTCTCA TACGTTTTGT AGAAATTGCT TGGAAAATGT TCTTCAAGCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR027370--Znf-RING_LisH
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00643--zf-B_box
PF13445--zf-RING_UBOX

SMART

SM00184--RING

Gene Ontology

GO:0005813--C:centrosome
GO:0005929--C:cilium
GO:0005783--C:endoplasmic reticulum
GO:0016021--C:integral component of membrane
GO:0030992--C:intraciliary transport particle B
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0060271--P:cilium assembly
GO:0045087--P:innate immune response
GO:0043124--P:negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0046597--P:negative regulation of viral entry into host cell

KEGG

fca:101093456

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002249	Ailuropoda melanoleuca	95.02	0.00e+00	780.00
IUUC-Apl-003996	Anas platyrhynchos	69.02	1.00e-123	436.00
IUUC-Aca-005141	Anolis carolinensis	58.27	7.00e-133	466.00
IUUC-Ame-011353	Astyanax mexicanus	52.09	3.00e-100	358.00
IUUC-Bta-013440	Bos taurus	93.92	0.00e+00	695.00
IUUC-Cfa-021168	Canis familiaris	96.01	0.00e+00	786.00
IUUC-Cpo-021702	Cavia porcellus	78.11	2.00e-180	624.00
IUUC-Csa-024141	Chlorocebus sabaeus	90.07	0.00e+00	681.00
IUUC-Dre-028408	Danio rerio	48.08	6.00e-91	327.00
IUUC-Dno-029180	Dasypus novemcinctus	91.07	0.00e+00	750.00
IUUC-Eca-034357	Equus caballus	93.05	0.00e+00	734.00
IUUC-Gga-040739	Gallus gallus	58.52	7.00e-136	476.00
IUUC-Ggo-045307	Gorilla gorilla	88.59	0.00e+00	714.00
IUUC-Hsa-045690	Homo sapiens	89.33	0.00e+00	715.00
IUUC-Itr-048230	Ictidomys tridecemlineatus	93.55	0.00e+00	776.00
IUUC-Laf-054522	Loxodonta africana	88.31	0.00e+00	731.00
IUUC-Mcc-055145	Macaca mulatta	90.57	0.00e+00	723.00
IUUC-Meu-056214	Macropus eugenii	47.77	1.00e-61	229.00
IUUC-Mmr-061197	Microcebus murinus	94.79	0.00e+00	785.00
IUUC-Mdo-062631	Monodelphis domestica	59.75	1.00e-134	472.00
IUUC-Mmu-064217	Mus musculus	86.82	0.00e+00	691.00
IUUC-Mpu-065691	Mustela putorius furo	97.52	0.00e+00	800.00
IUUC-Mlu-067742	Myotis lucifugus	90.75	0.00e+00	717.00
IUUC-Nle-069722	Nomascus leucogenys	89.83	0.00e+00	747.00
IUUC-Oan-073382	Ornithorhynchus anatinus	60.10	1.00e-136	479.00
IUUC-Olu-087666	Ostreococcus lucimarinus	33.33	2.00e-09	57.00
IUUC-Oar-089206	Ovis aries	92.31	0.00e+00	763.00
IUUC-Pan-092189	Papio anubis	90.82	0.00e+00	725.00
IUUC-Psi-093523	Pelodiscus sinensis	62.56	4.00e-144	504.00
IUUC-Pma-094162	Petromyzon marinus	33.44	2.00e-48	185.00
IUUC-Pfo-096032	Poecilia formosa	46.62	5.00e-89	321.00
IUUC-Pva-103089	Pteropus vampyrus	93.00	0.00e+00	736.00
IUUC-Pgr-103338	Puccinia graminis	38.71	1.00e-06	46.60
IUUC-Rno-105440	Rattus norvegicus	89.05	0.00e+00	708.00
IUUC-Ssc-115809	Sus scrofa	91.32	0.00e+00	726.00
IUUC-Tru-118402	Takifugu rubripes	44.07	3.00e-94	338.00
IUUC-Tni-119737	Tetraodon nigroviridis	45.02	1.00e-85	309.00
IUUC-Ttr-128921	Tursiops truncatus	92.00	0.00e+00	732.00
IUUC-Vpa-130397	Vicugna pacos	93.30	0.00e+00	772.00
IUUC-Xtr-132752	Xenopus tropicalis	44.17	2.00e-86	312.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence