iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-033828

UUCD1 version

UUC-EqC-00078

Ensembl Protein ID

ENSECAP00000022872.1

UniProt Accession

F6QSU1; F6QSU1_HORSE

Protein Name

Uncharacterized protein

Gene Name

UBE3C

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000008395.2	ENSECAT00000028892.1	ENSECAP00000022872.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	3.30e-105	352.3	725	1062

Active Site

Position(s)	Description	Evidence
1030	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 3    sdlkkrlevefvg.....EegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqd 84
            dlkkr++v++++     E+g+d gG++refl++l+k  +np+ g+f++++++    +p+ ++ + +    ++++flGr+lgkal++
   Q: 725  PDLKKRIRVHLLNahgldEAGIDGGGIFREFLNELLKSGFNPNQGFFKTTNEGLLYPNPAAQMLVGD-SFARHYYFLGRMLGKALYE 810
           689**********99**9************************************9999999999965.999**************** PP
   S: 85   grlldlplsksfyklllgk..klsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneN 169
           + l++lp++ +f+++llg+  ++++++l+++dpe+yk+l ++k++ e d+eelgl++t+   ++ lge++++eLk gG++ipVt +N
   Q: 811  NMLVELPFAGFFLSKLLGTsaDVDIHHLASLDPEVYKNLLFLKSY-EGDVEELGLNFTVV--NNDLGEAQVVELKFGGKDIPVTSAN 894
           ******************9666889******************99.78999987777765..888********************** PP
   S: 170  keeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGe.eeidvedlkketkykggytedspaiqwFwevlee 255
           + +Y++lv++yrl+++i++++ afr+G+ +v++le+l++F+++e+++li+G    i++edlk++t+y ggy++d+p+i+ Fw+v+e+
   Q: 895  RIAYIHLVADYRLNRQIRQHCLAFRQGLANVVNLEWLRMFDQQEIQVLISGAqVPISLEDLKSFTNYSGGYSADHPVIKVFWRVVEG 981
           ****************************************************899******************************** PP
   S: 256  fsseerkafLqFvTgssrlPlgGfaelkprlfvirkdasd.drlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFels 336
           f++ee++++L+FvT++sr Pl Gf+el p  f+i++ +sd +rlP+++TC+n+LkLPe+  ++ l++kLlyAie ++gFels
   Q: 982  FTDEEKRKLLKFVTSCSRPPLLGFKELYPA-FCIHNGGSDlERLPTASTCMNLLKLPEFYDETLLRSKLLYAIECAAGFELS 1062
           ****************************88.*****99999**************************************985 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

EEKASLLHRT QEERRKREEE RRRLKNAIII QSFIRGYRDR RQQYSIQRSS FDRCANLSQS 60
GGTFSLANGP NLTLLVRQLL FFYKQNEDSK RLIWLYQNLI KHSSLFVQQL DGSERLTCLF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAAGAAAAGG CTTCTCTTTT ACATCGTACT CAGGAAGAAA GAAGAAAGAG AGAGGTAAAA 60
ATAGTTTTGT AATAGTTTCT ATAGACAAGC ATTTTTCCAA AGCCTTTCAA TAAGTCTTGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom
IPR000048--IQ_motif_EF-hand-BS

PROSITE

PS50237--HECT
PS50096--IQ

Pfam

PF00632--HECT

SMART

SM00119--HECTc
SM00015--IQ

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity
GO:0000209--P:protein polyubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001355	Ailuropoda melanoleuca	94.44	0.00e+00	1951.00
IUUC-Apl-003731	Anas platyrhynchos	90.78	0.00e+00	1894.00
IUUC-Aca-005248	Anolis carolinensis	88.89	0.00e+00	1895.00
IUUC-Aly-005768	Arabidopsis lyrata	34.59	4.00e-109	389.00
IUUC-Ath-006576	Arabidopsis thaliana	33.47	3.00e-109	390.00
IUUC-Ago-007748	Ashbya gossypii	41.61	4.00e-77	283.00
IUUC-Acl-008158	Aspergillus clavatus	38.38	8.00e-77	282.00
IUUC-Afl-008398	Aspergillus flavus	37.87	8.00e-77	282.00
IUUC-Afu-008937	Aspergillus fumigatus	38.85	2.00e-79	290.00
IUUC-Ani-009252	Aspergillus nidulans	38.38	7.00e-81	295.00
IUUC-Ang-009773	Aspergillus niger	37.95	3.00e-77	283.00
IUUC-Aor-009940	Aspergillus oryzae	37.87	8.00e-77	282.00
IUUC-Ate-010395	Aspergillus terreus	39.02	3.00e-77	283.00
IUUC-Ame-010769	Astyanax mexicanus	62.95	0.00e+00	1036.00
IUUC-Bgr-012269	Blumeria graminis	37.99	7.00e-76	277.00
IUUC-Bta-012841	Bos taurus	92.00	0.00e+00	1904.00
IUUC-Bci-013743	Botrytis cinerea	29.88	2.00e-86	314.00
IUUC-Bdi-014123	Brachypodium distachyon	46.57	4.00e-102	365.00
IUUC-Bol-015390	Brassica oleracea	46.12	5.00e-101	362.00
IUUC-Bra-016853	Brassica rapa	34.74	6.00e-108	385.00
IUUC-Cel-018638	Caenorhabditis elegans	39.86	2.00e-90	327.00
IUUC-Cja-019743	Callithrix jacchus	93.19	0.00e+00	1934.00
IUUC-Cfa-021031	Canis familiaris	94.84	0.00e+00	1962.00
IUUC-Cpo-022401	Cavia porcellus	91.90	0.00e+00	1910.00
IUUC-Cre-022725	Chlamydomonas reinhardtii	43.99	2.00e-84	305.00
IUUC-Csa-024107	Chlorocebus sabaeus	95.20	0.00e+00	1962.00
IUUC-Cho-024750	Choloepus hoffmanni	83.54	0.00e+00	812.00
IUUC-Cin-025432	Ciona intestinalis	44.66	4.00e-98	351.00
IUUC-Cgl-026559	Colletotrichum gloeosporioides	34.49	3.00e-88	320.00
IUUC-Cne-026841	Cryptococcus neoformans	36.65	1.00e-93	337.00
IUUC-Cme-027265	Cyanidioschyzon merolae	46.86	7.00e-103	368.00
IUUC-Dre-028196	Danio rerio	77.40	0.00e+00	1567.00
IUUC-Dno-029024	Dasypus novemcinctus	95.29	0.00e+00	1982.00
IUUC-Dor-030483	Dipodomys ordii	91.12	0.00e+00	686.00
IUUC-Dse-031416	Dothistroma septosporum	34.08	4.00e-78	286.00
IUUC-Dme-031946	Drosophila melanogaster	36.71	0.00e+00	649.00
IUUC-Ete-032240	Echinops telfairi	85.34	2.00e-178	619.00
IUUC-Eeu-034604	Erinaceus europaeus	85.00	7.00e-126	444.00
IUUC-Fca-035907	Felis catus	93.97	0.00e+00	1966.00
IUUC-Fal-037389	Ficedula albicollis	90.58	0.00e+00	1915.00
IUUC-Fox-037788	Fusarium oxysporum	31.30	9.00e-92	331.00
IUUC-Fso-038088	Fusarium solani	36.38	7.00e-90	325.00
IUUC-Gmo-039254	Gadus morhua	65.71	0.00e+00	1188.00
IUUC-Ggr-039941	Gaeumannomyces graminis	33.80	2.00e-83	304.00
IUUC-Gga-040310	Gallus gallus	90.68	0.00e+00	1914.00
IUUC-Gac-042054	Gasterosteus aculeatus	68.13	0.00e+00	1246.00
IUUC-Gma-042836	Glycine max	33.86	2.00e-104	373.00
IUUC-Ggo-045031	Gorilla gorilla	95.57	0.00e+00	1971.00
IUUC-Hsa-045880	Homo sapiens	95.48	0.00e+00	1969.00
IUUC-Itr-048555	Ictidomys tridecemlineatus	84.83	0.00e+00	693.00
IUUC-Kpa-049307	Komagataella pastoris	36.52	1.00e-64	241.00
IUUC-Lch-050403	Latimeria chalumnae	81.26	0.00e+00	1637.00
IUUC-Loc-052218	Lepisosteus oculatus	80.92	0.00e+00	1668.00
IUUC-Lma-053096	Leptosphaeria maculans	38.58	7.00e-81	295.00
IUUC-Laf-054162	Loxodonta africana	90.90	0.00e+00	1711.00
IUUC-Mcc-055127	Macaca mulatta	95.29	0.00e+00	1966.00
IUUC-Meu-056187	Macropus eugenii	83.04	3.00e-106	379.00
IUUC-Mor-057021	Magnaporthe oryzae	35.02	8.00e-80	292.00
IUUC-Mpo-057570	Magnaporthe poae	36.68	9.00e-77	281.00
IUUC-Mtr-058154	Medicago truncatula	33.42	8.00e-106	378.00
IUUC-Mla-059124	Melampsora laricipopulina	48.28	3.00e-102	365.00
IUUC-Mga-059581	Meleagris gallopavo	90.77	0.00e+00	1916.00
IUUC-Mvi-060445	Microbotryum violaceum	37.58	3.00e-104	373.00
IUUC-Mmr-061360	Microcebus murinus	90.64	0.00e+00	1860.00
IUUC-Mdo-062194	Monodelphis domestica	90.96	0.00e+00	1925.00
IUUC-Mmu-064189	Mus musculus	91.24	0.00e+00	1932.00
IUUC-Mac-065275	Musa acuminata	49.39	7.00e-109	388.00
IUUC-Mpu-066439	Mustela putorius furo	93.41	0.00e+00	1935.00
IUUC-Mlu-068228	Myotis lucifugus	90.69	0.00e+00	1910.00
IUUC-Nfi-068280	Neosartorya fischeri	38.85	1.00e-79	291.00
IUUC-Ncr-068869	Neurospora crassa	35.61	7.00e-82	298.00
IUUC-Nle-069687	Nomascus leucogenys	94.92	0.00e+00	1957.00
IUUC-Opr-070592	Ochotona princeps	76.30	5.00e-123	435.00
IUUC-Ont-071836	Oreochromis niloticus	77.40	0.00e+00	1599.00
IUUC-Oan-072800	Ornithorhynchus anatinus	90.87	0.00e+00	1912.00
IUUC-Ocu-074587	Oryctolagus cuniculus	95.57	0.00e+00	1978.00
IUUC-Ola-087209	Oryzias latipes	76.93	0.00e+00	1570.00
IUUC-Olu-087699	Ostreococcus lucimarinus	42.86	3.00e-87	315.00
IUUC-Oga-088776	Otolemur garnettii	88.98	0.00e+00	1776.00
IUUC-Oar-089441	Ovis aries	90.79	0.00e+00	1877.00
IUUC-Ptr-091273	Pan troglodytes	95.39	0.00e+00	1968.00
IUUC-Pan-091981	Papio anubis	95.20	0.00e+00	1965.00
IUUC-Psi-093203	Pelodiscus sinensis	88.87	0.00e+00	1637.00
IUUC-Pma-094738	Petromyzon marinus	64.99	0.00e+00	1304.00
IUUC-Pno-095132	Phaeosphaeria nodorum	34.67	2.00e-57	217.00
IUUC-Ppa-095682	Physcomitrella patens	35.44	3.00e-113	403.00
IUUC-Pfo-097511	Poecilia formosa	77.44	0.00e+00	1612.00
IUUC-Pab-098634	Pongo abelii	92.29	0.00e+00	1887.00
IUUC-Pop-098928	Populus trichocarpa	34.79	5.00e-99	355.00
IUUC-Pca-100987	Procavia capensis	86.15	0.00e+00	868.00
IUUC-Pva-103034	Pteropus vampyrus	89.55	0.00e+00	1844.00
IUUC-Pgr-103513	Puccinia graminis	38.83	2.00e-106	380.00
IUUC-Ptt-103967	Puccinia triticina	33.42	3.00e-94	340.00
IUUC-Pte-104105	Pyrenophora teres	34.20	9.00e-81	295.00
IUUC-Pyt-104449	Pyrenophora triticirepentis	37.72	1.00e-78	288.00
IUUC-Rno-105380	Rattus norvegicus	90.33	0.00e+00	1664.00
IUUC-Sce-106446	Saccharomyces cerevisiae	40.77	9.00e-68	251.00
IUUC-Sha-107108	Sarcophilus harrisii	84.96	0.00e+00	1771.00
IUUC-Sja-107889	Schizosaccharomyces japonicus	43.19	7.00e-96	345.00
IUUC-Spo-108097	Schizosaccharomyces pombe	44.36	1.00e-94	341.00
IUUC-Ssl-108520	Sclerotinia sclerotiorum	30.03	6.00e-84	305.00
IUUC-Sly-111362	Solanum lycopersicum	35.63	2.00e-100	360.00
IUUC-Sar-113687	Sorex araneus	82.47	0.00e+00	919.00
IUUC-Sre-115038	Sporisorium reilianum	44.96	4.00e-99	356.00
IUUC-Ssc-116168	Sus scrofa	88.13	0.00e+00	775.00
IUUC-Tgu-116729	Taeniopygia guttata	90.50	0.00e+00	1908.00
IUUC-Tru-118068	Takifugu rubripes	75.37	0.00e+00	1565.00
IUUC-Tsy-118942	Tarsius syrichta	92.27	0.00e+00	724.00
IUUC-Tni-120732	Tetraodon nigroviridis	75.31	0.00e+00	1514.00
IUUC-Tre-121892	Trichoderma reesei	37.48	2.00e-89	324.00
IUUC-Tvi-122354	Trichoderma virens	36.06	6.00e-90	325.00
IUUC-Tme-127102	Tuber melanosporum	35.65	9.00e-92	332.00
IUUC-Tbe-127351	Tupaia belangeri	80.77	0.00e+00	1533.00
IUUC-Ttr-129061	Tursiops truncatus	91.53	0.00e+00	1872.00
IUUC-Uma-129343	Ustilago maydis	44.96	6.00e-100	358.00
IUUC-Vda-129748	Verticillium dahliae	34.56	3.00e-82	300.00
IUUC-Vvi-131234	Vitis vinifera	30.05	3.00e-104	373.00
IUUC-Xtr-132094	Xenopus tropicalis	85.24	0.00e+00	1749.00
IUUC-Xma-133923	Xiphophorus maculatus	77.73	0.00e+00	1615.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence