iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-034221

UUCD1 version

UUC-EqC-00967

Ensembl Protein ID

ENSECAP00000019943.1

UniProt Accession

F7B4D6; F7B4D6_HORSE

Protein Name

Uncharacterized protein

Gene Name

UBE2R2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000022482.1	ENSECAT00000024031.1	ENSECAP00000019943.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	4.40e-32	110.9	1	96

Active Site

Position(s)	Description	Evidence
36	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 47   FkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilk...........eeekWspalsvesvllsiqsllaepnpesplneeaae 124
           F+++i+fp dYP++PP+++fltk++hPn+yenG+vC+sil+           ++e+W+p+++v+++lls++sll+epn+ sp+n++a+ 
   Q: 1    FQAHIKFPIDYPYSPPTFRFLTKMWHPNIYENGDVCISILHppvddpqsgelPSERWNPTQNVRTILLSVISLLNEPNTFSPANVDASV 89
           99**************************************999999999*9*************************************9 PP
   S: 125  llkknre 131
           +++k+r 
   Q: 90   MFRKWRD 96
           9998875 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

FQAHIKFPID YPYSPPTFRF LTKMWHPNIY ENGDVCISIL HPPVDDPQSG ELPSERWNPT 60
QNVRTILLSV ISLLNEPNTF SPANVDASVM FRKWRDSKGK DKEYAEIIRK QVSATKAEAE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTTCAGGCGC ATATTAAATT TCCTATTGAC TACCCATATT CACCACCTAC CTTCAGATTC 60
TTGACCAAAA TGTGGCACCC CAACATTTAT GAGGTAAGAA ACGTCTATCA TGAATTTCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005524--F:ATP binding
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0031625--F:ubiquitin protein ligase binding
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0070936--P:protein K48-linked ubiquitination
GO:0006513--P:protein monoubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001600	Ailuropoda melanoleuca	84.93	5.00e-74	270.00
IUUC-Apl-003563	Anas platyrhynchos	99.32	6.00e-84	302.00
IUUC-Aca-004589	Anolis carolinensis	97.95	7.00e-84	303.00
IUUC-Ani-009262	Aspergillus nidulans	50.78	1.00e-27	116.00
IUUC-Ate-010563	Aspergillus terreus	47.79	4.00e-28	117.00
IUUC-Ame-011300	Astyanax mexicanus	94.37	2.00e-79	288.00
IUUC-Bta-012968	Bos taurus	99.32	4.00e-84	303.00
IUUC-Bci-013915	Botrytis cinerea	58.70	3.00e-29	121.00
IUUC-Cel-018460	Caenorhabditis elegans	69.85	4.00e-56	210.00
IUUC-Cja-018764	Callithrix jacchus	99.32	1.00e-84	305.00
IUUC-Cfa-020955	Canis familiaris	99.32	1.00e-84	305.00
IUUC-Cpo-021451	Cavia porcellus	99.32	1.00e-84	305.00
IUUC-Csa-024239	Chlorocebus sabaeus	99.32	1.00e-84	305.00
IUUC-Cin-025257	Ciona intestinalis	74.66	3.00e-65	241.00
IUUC-Csv-025954	Ciona savignyi	76.71	2.00e-66	245.00
IUUC-Dre-028153	Danio rerio	93.15	3.00e-80	291.00
IUUC-Dno-029368	Dasypus novemcinctus	99.32	4.00e-84	303.00
IUUC-Dor-030686	Dipodomys ordii	99.32	1.00e-84	305.00
IUUC-Dme-032106	Drosophila melanogaster	75.34	2.00e-65	242.00
IUUC-Ete-033001	Echinops telfairi	100.00	2.00e-64	237.00
IUUC-Fca-036381	Felis catus	99.31	2.00e-83	301.00
IUUC-Fal-037135	Ficedula albicollis	98.63	1.00e-83	302.00
IUUC-Gmo-039565	Gadus morhua	93.66	6.00e-79	286.00
IUUC-Gga-040477	Gallus gallus	98.63	8.00e-84	302.00
IUUC-Gac-041909	Gasterosteus aculeatus	92.96	9.00e-79	285.00
IUUC-Ggo-045150	Gorilla gorilla	98.63	8.00e-84	302.00
IUUC-Hsa-046611	Homo sapiens	99.32	1.00e-84	305.00
IUUC-Itr-047928	Ictidomys tridecemlineatus	87.14	7.00e-73	265.00
IUUC-Lch-050173	Latimeria chalumnae	97.95	2.00e-83	301.00
IUUC-Loc-051916	Lepisosteus oculatus	95.83	5.00e-79	287.00
IUUC-Laf-053860	Loxodonta africana	99.32	1.00e-84	305.00
IUUC-Mcc-054820	Macaca mulatta	99.32	1.00e-84	305.00
IUUC-Meu-056681	Macropus eugenii	91.10	1.00e-76	278.00
IUUC-Mga-059396	Meleagris gallopavo	99.26	1.00e-78	284.00
IUUC-Mmr-060666	Microcebus murinus	99.32	1.00e-84	305.00
IUUC-Mdo-062804	Monodelphis domestica	98.63	6.00e-84	303.00
IUUC-Mmu-063472	Mus musculus	99.32	1.00e-84	305.00
IUUC-Mpu-066301	Mustela putorius furo	99.31	1.00e-83	301.00
IUUC-Mlu-067620	Myotis lucifugus	100.00	1.00e-84	305.00
IUUC-Nle-070152	Nomascus leucogenys	100.00	2.00e-63	233.00
IUUC-Opr-070826	Ochotona princeps	82.88	2.00e-70	258.00
IUUC-Ont-071627	Oreochromis niloticus	93.71	1.00e-79	289.00
IUUC-Oan-073287	Ornithorhynchus anatinus	83.56	2.00e-73	268.00
IUUC-Ocu-074229	Oryctolagus cuniculus	99.32	4.00e-84	303.00
IUUC-Ola-086587	Oryzias latipes	92.96	5.00e-79	286.00
IUUC-Oga-089161	Otolemur garnettii	99.32	2.00e-84	304.00
IUUC-Oar-089383	Ovis aries	99.32	1.00e-84	305.00
IUUC-Ptr-091096	Pan troglodytes	99.32	1.00e-84	305.00
IUUC-Pan-092560	Papio anubis	99.32	4.00e-84	303.00
IUUC-Psi-093263	Pelodiscus sinensis	99.32	5.00e-84	302.00
IUUC-Pma-094368	Petromyzon marinus	87.41	2.00e-74	270.00
IUUC-Pfo-096974	Poecilia formosa	93.62	8.00e-79	286.00
IUUC-Pab-098344	Pongo abelii	99.32	1.00e-84	305.00
IUUC-Pca-100169	Procavia capensis	78.52	6.00e-60	222.00
IUUC-Pva-102875	Pteropus vampyrus	85.42	6.00e-73	266.00
IUUC-Rno-105821	Rattus norvegicus	99.32	1.00e-84	305.00
IUUC-Sha-107364	Sarcophilus harrisii	98.63	6.00e-84	303.00
IUUC-Ssl-108409	Sclerotinia sclerotiorum	50.00	2.00e-31	129.00
IUUC-Sar-112992	Sorex araneus	98.63	6.00e-84	303.00
IUUC-Ssc-115699	Sus scrofa	81.51	4.00e-71	259.00
IUUC-Tgu-117074	Taeniopygia guttata	98.63	1.00e-83	302.00
IUUC-Tru-118641	Takifugu rubripes	93.57	2.00e-78	285.00
IUUC-Tsy-118797	Tarsius syrichta	97.10	3.00e-77	280.00
IUUC-Tni-119817	Tetraodon nigroviridis	92.96	7.00e-79	286.00
IUUC-Tme-127042	Tuber melanosporum	53.26	2.00e-26	112.00
IUUC-Tbe-128014	Tupaia belangeri	99.32	1.00e-84	305.00
IUUC-Ttr-129037	Tursiops truncatus	99.32	5.00e-84	303.00
IUUC-Vpa-130680	Vicugna pacos	100.00	2.00e-83	300.00
IUUC-Xtr-131819	Xenopus tropicalis	99.29	4.00e-81	293.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence