iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ocu-073765

UUCD1 version

UUC-OrC-00427

Ensembl Protein ID

ENSOCUP00000010031.2

UniProt Accession

G1T1Q6; G1T1Q6_RABIT

Protein Name

Uncharacterized protein

Gene Name

KLHL25

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000011669.2	ENSOCUT00000011667.2	ENSOCUP00000010031.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	6.00e-20	71.4	46	114
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	9.10e-09	34.5	146	176

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikd.vqpevfrallkFlYtgkldene 69
           +Dv+l  gg+ f++h++vLaasS++F+a+f+++l+es+  ++v+++d + pev+  ll+F Y++++ +ne
   Q: 46   TDVTLWAGGRAFPCHRAVLAASSRYFEAMFSHGLRESR-DDTVDFQDnLHPEVLALLLDFAYSSRIVINE 114
           7*************************************.*******99*****************99886 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhF 31
           ++Ncl  l +Ad+++c++L+++  +++l hF
   Q: 146  PSNCLRTLLLADAHQCRRLHEFSWRMCLLHF 176
           89*************************9999 PP

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

MSVSVHETRK SRGSTGSMNI TLFHKASHPD CVLAHLNTLR QHRVLTDVTL WAGGRAFPCH 60
RAVLAASSRY FEAMFSHGLR ESRDDTVDFQ DNLHPEVLAL LLDFAYSSRI VINEENAESL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCGGTCA GCGTCCATGA GACCCGGAAG TCGCGGGGCA GCACAGGCTC CATGAACATC 60
ACGCTCTTCC ACAAGGCCTC GCACCCCGAC TGCGTGCTGG CCCACCTCAA CACACTGCGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030565--KLHL25
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0006446--P:regulation of translational initiation

KEGG

ocu:100340873

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002373	Ailuropoda melanoleuca	90.15	0.00e+00	1109.00
IUUC-Apl-003543	Anas platyrhynchos	85.59	0.00e+00	1029.00
IUUC-Aca-004729	Anolis carolinensis	82.51	0.00e+00	1012.00
IUUC-Ame-011020	Astyanax mexicanus	81.66	0.00e+00	974.00
IUUC-Bta-012955	Bos taurus	91.34	0.00e+00	1116.00
IUUC-Cja-018839	Callithrix jacchus	89.98	0.00e+00	1108.00
IUUC-Cfa-020224	Canis familiaris	90.66	0.00e+00	1117.00
IUUC-Cpo-021593	Cavia porcellus	88.46	0.00e+00	1052.00
IUUC-Csa-023276	Chlorocebus sabaeus	90.32	0.00e+00	1111.00
IUUC-Dre-028053	Danio rerio	82.00	0.00e+00	951.00
IUUC-Dno-029287	Dasypus novemcinctus	90.15	0.00e+00	1105.00
IUUC-Dor-030908	Dipodomys ordii	83.53	0.00e+00	1001.00
IUUC-Dse-031490	Dothistroma septosporum	27.08	2.00e-05	42.70
IUUC-Fca-035897	Felis catus	90.66	0.00e+00	1112.00
IUUC-Fal-037036	Ficedula albicollis	85.74	0.00e+00	1034.00
IUUC-Gmo-039345	Gadus morhua	81.66	0.00e+00	957.00
IUUC-Gga-040404	Gallus gallus	85.40	0.00e+00	1033.00
IUUC-Gac-042447	Gasterosteus aculeatus	81.49	0.00e+00	966.00
IUUC-Ggo-045060	Gorilla gorilla	90.15	0.00e+00	1109.00
IUUC-Hsa-046494	Homo sapiens	90.15	0.00e+00	1108.00
IUUC-Itr-047993	Ictidomys tridecemlineatus	90.49	0.00e+00	1115.00
IUUC-Lch-050211	Latimeria chalumnae	82.31	0.00e+00	989.00
IUUC-Loc-052578	Lepisosteus oculatus	81.15	0.00e+00	978.00
IUUC-Laf-053498	Loxodonta africana	89.64	0.00e+00	1071.00
IUUC-Mcc-055033	Macaca mulatta	90.49	0.00e+00	1112.00
IUUC-Meu-056893	Macropus eugenii	86.76	0.00e+00	1067.00
IUUC-Mga-060025	Meleagris gallopavo	85.57	0.00e+00	1033.00
IUUC-Mmr-060658	Microcebus murinus	90.15	0.00e+00	1106.00
IUUC-Mdo-062667	Monodelphis domestica	86.93	0.00e+00	1072.00
IUUC-Mmu-063125	Mus musculus	87.27	0.00e+00	1049.00
IUUC-Mpu-066209	Mustela putorius furo	90.49	0.00e+00	1113.00
IUUC-Mlu-068237	Myotis lucifugus	89.81	0.00e+00	1069.00
IUUC-Nle-069454	Nomascus leucogenys	90.05	0.00e+00	1095.00
IUUC-Ont-072138	Oreochromis niloticus	81.49	0.00e+00	956.00
IUUC-Oan-073320	Ornithorhynchus anatinus	83.53	0.00e+00	1023.00
IUUC-Oga-088002	Otolemur garnettii	89.98	0.00e+00	1103.00
IUUC-Oar-089481	Ovis aries	91.17	0.00e+00	1114.00
IUUC-Ptr-091200	Pan troglodytes	89.98	0.00e+00	1105.00
IUUC-Psi-093884	Pelodiscus sinensis	84.72	0.00e+00	1021.00
IUUC-Pno-095143	Phaeosphaeria nodorum	26.83	1.00e-14	73.90
IUUC-Pab-098588	Pongo abelii	80.17	0.00e+00	954.00
IUUC-Pva-102321	Pteropus vampyrus	90.49	0.00e+00	1112.00
IUUC-Rno-104835	Rattus norvegicus	86.76	0.00e+00	1045.00
IUUC-Sha-107528	Sarcophilus harrisii	86.25	0.00e+00	1066.00
IUUC-Ssc-116161	Sus scrofa	90.83	0.00e+00	1111.00
IUUC-Tgu-116569	Taeniopygia guttata	85.57	0.00e+00	1030.00
IUUC-Tni-120525	Tetraodon nigroviridis	75.63	0.00e+00	855.00
IUUC-Ttr-129297	Tursiops truncatus	90.66	0.00e+00	1113.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence