iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aml-001789

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ACTA01123185

Gene Name

SOCS4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMEG00000020091.1	ENSAMET00000021914.1	ENSAMEP00000021145.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	4.90e-17	61.6	378	425

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box

   S: 3    klwllrseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlyedyq 53
           +++l+r+ p+SLqh+CR +I++c++++++   d+LP+P+s+k YL++++y+
   Q: 378  STPLIRTFPFSLQHICRTVICNCTTYDGI---DALPIPSSMKLYLKEYHYK 425
           678899***********************...****************985 PP

Organism

Ailuropoda melanoleuca

Protein Sequence
(Fasta)

MAENNESNSK NVDVRPKTSR SRSADRKDGY VWSGKKLSWS KKSESCSDAE AVNAVEKTEV 60
PLRSQERKYS CSSIELDLDH SCGHRFLGRS LKQKLQDAVG QCFPIKNCSG RHSSGLPSKR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCAGAAA ATAATGAAAG TAATAGCAAA AATGTAGATG TAAGGCCCAA AACTAGTCGA 60
AGTAGAAGTG CTGACAGAAA GGACGGTTAT GTGTGGAGTG GAAAGAAATT ATCTTGGTCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000980--SH2
IPR028416--SOCS4
IPR022252--SOCS4/SOCS5_dom
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2
PF12610--SOCS
PF07525--SOCS_box

SMART

SM00252--SH2
SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0005622--C:intracellular
GO:0035556--P:intracellular signal transduction
GO:0007175--P:negative regulation of epidermal growth factor-activated receptor activity
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0016567--P:protein ubiquitination

KEGG

aml:100464791

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003839	Anas platyrhynchos	80.82	0.00e+00	646.00
IUUC-Aca-004840	Anolis carolinensis	79.22	0.00e+00	697.00
IUUC-Ame-010677	Astyanax mexicanus	72.82	4.00e-86	311.00
IUUC-Bta-012503	Bos taurus	94.98	0.00e+00	799.00
IUUC-Bol-016597	Brassica oleracea	29.11	1.70e-01	31.20
IUUC-Cja-019284	Callithrix jacchus	93.85	0.00e+00	786.00
IUUC-Cfa-020890	Canis familiaris	95.43	0.00e+00	805.00
IUUC-Cpo-022081	Cavia porcellus	78.30	0.00e+00	681.00
IUUC-Csa-023076	Chlorocebus sabaeus	92.92	0.00e+00	786.00
IUUC-Cho-024700	Choloepus hoffmanni	94.31	0.00e+00	834.00
IUUC-Dre-028262	Danio rerio	72.82	2.00e-84	306.00
IUUC-Dno-029961	Dasypus novemcinctus	94.31	0.00e+00	828.00
IUUC-Dor-030273	Dipodomys ordii	93.39	0.00e+00	791.00
IUUC-Dme-031965	Drosophila melanogaster	65.88	1.00e-67	251.00
IUUC-Ete-032972	Echinops telfairi	94.19	8.00e-173	599.00
IUUC-Eca-034289	Equus caballus	94.76	0.00e+00	797.00
IUUC-Eeu-035208	Erinaceus europaeus	92.18	0.00e+00	762.00
IUUC-Fca-035806	Felis catus	53.76	3.00e-117	415.00
IUUC-Fal-036829	Ficedula albicollis	81.51	0.00e+00	647.00
IUUC-Gmo-039066	Gadus morhua	72.45	8.00e-84	304.00
IUUC-Gga-040725	Gallus gallus	79.91	0.00e+00	668.00
IUUC-Gac-042149	Gasterosteus aculeatus	50.68	3.00e-104	372.00
IUUC-Ggo-044886	Gorilla gorilla	93.62	0.00e+00	788.00
IUUC-Hsa-046322	Homo sapiens	93.39	0.00e+00	786.00
IUUC-Itr-048585	Ictidomys tridecemlineatus	94.24	0.00e+00	797.00
IUUC-Lch-049459	Latimeria chalumnae	57.53	7.00e-138	483.00
IUUC-Loc-051745	Lepisosteus oculatus	77.44	4.00e-89	322.00
IUUC-Laf-053484	Loxodonta africana	95.16	0.00e+00	793.00
IUUC-Mcc-054890	Macaca mulatta	92.69	0.00e+00	784.00
IUUC-Meu-056532	Macropus eugenii	83.29	0.00e+00	638.00
IUUC-Mga-059214	Meleagris gallopavo	52.91	1.00e-116	413.00
IUUC-Mvi-060418	Microbotryum violaceum	32.10	1.60e-02	32.70
IUUC-Mmr-061714	Microcebus murinus	94.76	0.00e+00	791.00
IUUC-Mdo-062788	Monodelphis domestica	51.97	2.00e-114	405.00
IUUC-Mmu-063161	Mus musculus	88.36	0.00e+00	748.00
IUUC-Mpu-066499	Mustela putorius furo	96.60	0.00e+00	840.00
IUUC-Mlu-066945	Myotis lucifugus	93.17	0.00e+00	781.00
IUUC-Nle-069976	Nomascus leucogenys	93.39	0.00e+00	785.00
IUUC-Opr-070255	Ochotona princeps	89.27	0.00e+00	764.00
IUUC-Ont-072537	Oreochromis niloticus	80.23	5.00e-86	311.00
IUUC-Ocu-074764	Oryctolagus cuniculus	94.31	0.00e+00	793.00
IUUC-Ola-086934	Oryzias latipes	51.29	6.00e-104	371.00
IUUC-Oga-088910	Otolemur garnettii	89.09	0.00e+00	777.00
IUUC-Oar-090330	Ovis aries	94.75	0.00e+00	796.00
IUUC-Ptr-090709	Pan troglodytes	93.62	0.00e+00	788.00
IUUC-Pan-092540	Papio anubis	92.92	0.00e+00	786.00
IUUC-Psi-093678	Pelodiscus sinensis	82.65	0.00e+00	726.00
IUUC-Pma-094222	Petromyzon marinus	79.65	3.00e-85	309.00
IUUC-Pfo-097139	Poecilia formosa	80.81	4.00e-87	315.00
IUUC-Pab-097970	Pongo abelii	91.71	0.00e+00	649.00
IUUC-Pop-098820	Populus trichocarpa	41.18	1.30e-01	30.80
IUUC-Pca-100211	Procavia capensis	82.69	0.00e+00	662.00
IUUC-Pva-102387	Pteropus vampyrus	52.79	4.00e-113	401.00
IUUC-Rno-106014	Rattus norvegicus	86.04	0.00e+00	736.00
IUUC-Sha-106822	Sarcophilus harrisii	83.37	0.00e+00	713.00
IUUC-Sar-113698	Sorex araneus	56.53	1.00e-105	376.00
IUUC-Ssc-115821	Sus scrofa	94.99	0.00e+00	795.00
IUUC-Tgu-117117	Taeniopygia guttata	81.51	0.00e+00	647.00
IUUC-Tru-118441	Takifugu rubripes	56.63	5.00e-60	225.00
IUUC-Tsy-118979	Tarsius syrichta	96.15	8.00e-126	442.00
IUUC-Tni-120436	Tetraodon nigroviridis	50.47	3.00e-106	379.00
IUUC-Tca-121131	Theobroma cacao	30.77	2.00e-03	36.60
IUUC-Tbe-127353	Tupaia belangeri	52.79	4.00e-113	401.00
IUUC-Ttr-128907	Tursiops truncatus	53.02	2.00e-113	402.00
IUUC-Vpa-130626	Vicugna pacos	94.53	0.00e+00	800.00
IUUC-Vvi-131327	Vitis vinifera	43.75	9.70e-02	31.20
IUUC-Xtr-132138	Xenopus tropicalis	72.37	2.00e-176	611.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence