iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Pab-097970

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Suppressor of cytokine-signaling 4

Genbank Nucleotide ID

ABGA01012308

Gene Name

SOCS4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPPYG00000005835.2	ENSPPYT00000006892.2	ENSPPYP00000006629.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	98.66	0.00e+00	700.00	IUUC-Hsa-046322

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Pongo abelii

Protein Sequence
(Fasta)

MAENNENISK NVDVRPKTSR SRSADRKDGY VWSGKKLSWS KKSESYSDAE TVNGIEKTEV 60
SLRNQERKHS CSSIELDLDH SCGHRFLGRS LKQKLQDAVG QCFPIKNCSS RHSSGLPSKR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGTGACCGAG CCGCCGCGAC TGAGGATCCA CAAGAGCCGC TTCCCGCGCT TCGGCTCGCT 60
CACCACACTG CGCCTGCGCC GACCCGCCCA CGCCCAGAGC AGGTCCCTAC AGAGGTCGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000980--SH2
IPR028416--SOCS4
IPR022252--SOCS4/SOCS5_dom

PROSITE

PS50001--SH2

Pfam

PF00017--SH2
PF12610--SOCS

SMART

SM00252--SH2

Gene Ontology

GO:0007175--P:negative regulation of epidermal growth factor-activated receptor activity
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001789	Ailuropoda melanoleuca	91.71	0.00e+00	650.00
IUUC-Apl-003839	Anas platyrhynchos	76.41	4.00e-144	504.00
IUUC-Aca-004840	Anolis carolinensis	77.75	5.00e-164	570.00
IUUC-Bta-012503	Bos taurus	91.18	0.00e+00	640.00
IUUC-Cja-019284	Callithrix jacchus	96.51	0.00e+00	684.00
IUUC-Cfa-020890	Canis familiaris	92.23	0.00e+00	660.00
IUUC-Cpo-022081	Cavia porcellus	74.93	1.00e-153	536.00
IUUC-Cre-022608	Chlamydomonas reinhardtii	38.30	1.60e+00	28.90
IUUC-Csa-023076	Chlorocebus sabaeus	97.86	0.00e+00	691.00
IUUC-Cho-024700	Choloepus hoffmanni	91.44	0.00e+00	685.00
IUUC-Dno-029961	Dasypus novemcinctus	92.78	0.00e+00	688.00
IUUC-Dor-030273	Dipodomys ordii	90.91	0.00e+00	653.00
IUUC-Ete-032972	Echinops telfairi	88.98	1.00e-126	446.00
IUUC-Eca-034289	Equus caballus	92.51	0.00e+00	653.00
IUUC-Eeu-035208	Erinaceus europaeus	87.97	2.00e-176	611.00
IUUC-Fal-036829	Ficedula albicollis	76.68	1.00e-143	502.00
IUUC-Gga-040725	Gallus gallus	75.87	2.00e-152	531.00
IUUC-Ggo-044886	Gorilla gorilla	98.93	0.00e+00	702.00
IUUC-Hsa-046322	Homo sapiens	98.66	0.00e+00	700.00
IUUC-Itr-048585	Ictidomys tridecemlineatus	91.87	0.00e+00	651.00
IUUC-Lch-049459	Latimeria chalumnae	54.79	4.00e-110	391.00
IUUC-Laf-053484	Loxodonta africana	92.68	0.00e+00	647.00
IUUC-Mcc-054890	Macaca mulatta	97.86	0.00e+00	691.00
IUUC-Meu-056532	Macropus eugenii	82.89	3.00e-171	594.00
IUUC-Mmr-061714	Microcebus murinus	94.39	0.00e+00	661.00
IUUC-Mmu-063161	Mus musculus	84.99	5.00e-175	607.00
IUUC-Mac-064598	Musa acuminata	27.94	2.00e-02	32.00
IUUC-Mpu-066499	Mustela putorius furo	92.00	0.00e+00	682.00
IUUC-Mlu-066945	Myotis lucifugus	91.18	0.00e+00	642.00
IUUC-Nle-069976	Nomascus leucogenys	98.39	0.00e+00	697.00
IUUC-Opr-070255	Ochotona princeps	85.83	1.00e-177	615.00
IUUC-Ocu-074764	Oryctolagus cuniculus	91.18	0.00e+00	647.00
IUUC-Oga-088910	Otolemur garnettii	85.87	0.00e+00	630.00
IUUC-Oar-090330	Ovis aries	91.18	0.00e+00	637.00
IUUC-Ptr-090709	Pan troglodytes	98.93	0.00e+00	702.00
IUUC-Pan-092540	Papio anubis	97.86	0.00e+00	691.00
IUUC-Psi-093678	Pelodiscus sinensis	79.36	3.00e-170	591.00
IUUC-Pop-098820	Populus trichocarpa	41.18	1.20e-01	30.80
IUUC-Pca-100211	Procavia capensis	78.61	3.00e-149	521.00
IUUC-Rno-106014	Rattus norvegicus	82.84	8.00e-174	602.00
IUUC-Sha-106822	Sarcophilus harrisii	81.82	4.00e-170	590.00
IUUC-Ssc-115821	Sus scrofa	91.44	0.00e+00	645.00
IUUC-Tgu-117117	Taeniopygia guttata	77.21	1.00e-144	506.00
IUUC-Vpa-130626	Vicugna pacos	91.18	0.00e+00	647.00
IUUC-Vvi-131327	Vitis vinifera	43.75	9.80e-02	31.20

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence