iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Nle-068986

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADFV01165511

Gene Name

RNF146

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSNLEG00000014130.2	ENSNLET00000032823.1	ENSNLEP00000024456.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	99.16	3.00e-179	625.00	IUUC-Hsa-045790

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Nomascus leucogenys

Protein Sequence
(Fasta)

MMAGCGEIDH SINMLPTNRK ANESCSNTAP SLTVPECAIC LQTCVHPVSL PCKHVFCYLC 60
VKGASWLGKR CALCRQEIPE DFLDKPTLLS PEELKAASRG NGEYAWYYEG RNGWWQYDER 120

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Nucleotide Sequence
(Fasta)

CACAAAGAAT GAACCAGCAG TGGAAGAGAA AATACTGTAA GCTGGCTGAC TGCTGGTGAA 60
GAAAATGCTT TATTTTTATG GCAGGCATCT GTGGGATCTG TAATAGAAAT GTAAGTGTAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR033509--RNF146
IPR004170--WWE-dom
IPR018123--WWE-dom_subgr
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50918--WWE
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF02825--WWE

SMART

SM00184--RING
SM00678--WWE

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0005886--C:plasma membrane
GO:0072572--F:poly-ADP-D-ribose binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0090263--P:positive regulation of canonical Wnt signaling pathway
GO:0051865--P:protein autoubiquitination
GO:0070936--P:protein K48-linked ubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0016055--P:Wnt signaling pathway

KEGG

nle:100590342

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002237	Ailuropoda melanoleuca	91.09	1.00e-154	538.00
IUUC-Apl-004143	Anas platyrhynchos	84.44	3.00e-134	471.00
IUUC-Aca-004557	Anolis carolinensis	81.16	6.00e-128	450.00
IUUC-Ame-011088	Astyanax mexicanus	61.09	1.00e-83	302.00
IUUC-Bta-012639	Bos taurus	92.48	5.00e-150	523.00
IUUC-Cel-018462	Caenorhabditis elegans	28.35	6.00e-19	87.40
IUUC-Cja-019397	Callithrix jacchus	98.89	8.00e-166	576.00
IUUC-Cfa-021140	Canis familiaris	90.81	2.00e-165	575.00
IUUC-Cpo-021387	Cavia porcellus	89.97	6.00e-166	576.00
IUUC-Csa-023503	Chlorocebus sabaeus	93.59	7.00e-157	546.00
IUUC-Cho-024895	Choloepus hoffmanni	92.76	1.00e-143	502.00
IUUC-Cin-025455	Ciona intestinalis	51.92	4.00e-43	167.00
IUUC-Dre-028824	Danio rerio	45.99	4.00e-83	301.00
IUUC-Dno-029269	Dasypus novemcinctus	94.43	2.00e-160	558.00
IUUC-Dor-030592	Dipodomys ordii	93.61	1.00e-163	568.00
IUUC-Dme-031618	Drosophila melanogaster	57.33	1.00e-55	210.00
IUUC-Ete-032478	Echinops telfairi	92.20	2.00e-162	565.00
IUUC-Eca-033389	Equus caballus	95.81	6.00e-180	622.00
IUUC-Fca-035488	Felis catus	95.53	1.00e-162	565.00
IUUC-Fal-037087	Ficedula albicollis	83.61	4.00e-154	536.00
IUUC-Gga-040401	Gallus gallus	85.56	1.00e-138	485.00
IUUC-Gac-042412	Gasterosteus aculeatus	64.53	1.00e-87	316.00
IUUC-Ggo-045417	Gorilla gorilla	98.76	1.00e-159	555.00
IUUC-Hsa-045790	Homo sapiens	99.16	1.00e-166	578.00
IUUC-Itr-048820	Ictidomys tridecemlineatus	94.41	7.00e-165	572.00
IUUC-Lch-049493	Latimeria chalumnae	69.08	2.00e-110	391.00
IUUC-Loc-052927	Lepisosteus oculatus	66.78	2.00e-101	362.00
IUUC-Laf-053904	Loxodonta africana	93.04	8.00e-159	552.00
IUUC-Mcc-055427	Macaca mulatta	93.61	1.00e-162	565.00
IUUC-Mmr-060580	Microcebus murinus	96.39	2.00e-158	551.00
IUUC-Mdo-062094	Monodelphis domestica	96.97	1.00e-78	284.00
IUUC-Mmu-063363	Mus musculus	92.20	1.00e-164	572.00
IUUC-Mpu-066816	Mustela putorius furo	94.43	1.00e-156	545.00
IUUC-Mlu-067433	Myotis lucifugus	94.43	2.00e-179	621.00
IUUC-Ont-072670	Oreochromis niloticus	58.42	4.00e-81	294.00
IUUC-Oan-073330	Ornithorhynchus anatinus	87.06	3.00e-107	380.00
IUUC-Ocu-074161	Oryctolagus cuniculus	93.33	3.00e-164	570.00
IUUC-Ola-086902	Oryzias latipes	58.91	4.00e-84	304.00
IUUC-Oga-089159	Otolemur garnettii	94.15	0.00e+00	636.00
IUUC-Oar-089586	Ovis aries	93.59	2.00e-145	508.00
IUUC-Ptr-090987	Pan troglodytes	99.16	1.00e-166	578.00
IUUC-Pan-091867	Papio anubis	93.59	1.00e-161	562.00
IUUC-Psi-094024	Pelodiscus sinensis	85.28	1.00e-142	498.00
IUUC-Pma-094453	Petromyzon marinus	63.91	4.00e-65	241.00
IUUC-Pfo-097108	Poecilia formosa	70.73	1.00e-83	303.00
IUUC-Pab-097997	Pongo abelii	97.21	3.00e-172	597.00
IUUC-Pca-100260	Procavia capensis	92.18	7.00e-164	569.00
IUUC-Pva-103140	Pteropus vampyrus	94.17	3.00e-165	573.00
IUUC-Rno-105795	Rattus norvegicus	86.39	2.00e-162	564.00
IUUC-Sha-107033	Sarcophilus harrisii	88.06	5.00e-155	540.00
IUUC-Ssc-116395	Sus scrofa	96.94	0.00e+00	629.00
IUUC-Tgu-116685	Taeniopygia guttata	81.39	8.00e-135	473.00
IUUC-Tru-118014	Takifugu rubripes	74.88	5.00e-84	303.00
IUUC-Tsy-119326	Tarsius syrichta	89.72	4.00e-176	610.00
IUUC-Tni-120322	Tetraodon nigroviridis	69.95	4.00e-82	297.00
IUUC-Tbe-128067	Tupaia belangeri	95.00	3.00e-170	590.00
IUUC-Ttr-128530	Tursiops truncatus	95.83	3.00e-163	567.00
IUUC-Vpa-130322	Vicugna pacos	96.94	2.00e-171	594.00
IUUC-Xtr-132606	Xenopus tropicalis	65.92	8.00e-118	416.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence