iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-054376

UUCD1 version

UUC-LoA-00459

Ensembl Protein ID

ENSLAFP00000011215.3

UniProt Accession

G3TB84; G3TB84_LOXAF

Protein Name

Uncharacterized protein

Gene Name

TRAF4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000013400.3	ENSLAFT00000013403.3	ENSLAFP00000011215.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	9.50e-06	26.0	15	72
E3 activity/RING/RING	3.00e-06	28.0	18	56

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 5    eflCpIslelMrdPvvlp.sGitydrssIekwlasggktcPvtrqplteedlvPnltl 61
            +lCp+ +++Mr+Pv ++ +G+ +  ++++++l++g  +cP ++ pl+  ++ P  +l
   Q: 15   RLLCPLCGKPMREPVQVStCGHRFCDTCLQEFLSEGVFKCPEDQLPLDYAKIYPDPEL 72
           689*************999*****************99*********99999998776 PP

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPl 44
           C++C  ++++++ v  CgH f+ +Clq +     +s + f+CP 
   Q: 18   CPLCGKPMREPVQVSTCGHRFCDTCLQEF-----LSEGVFKCPE 56
           ********99888888**********999.....89*******6 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MPGFDYKFLE KPKRRLLCPL CGKPMREPVQ VSTCGHRFCD TCLQEFLSEG VFKCPEDQLP 60
LDYAKIYPDP ELEVQVLGLL IRCIHSEEGC RWSGPLRHLQ GHLNTCSFNV VPCPNRCPTK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCCCGGTT TCGACTACAA GTTCCTGGAG AAGCCCAAGC GGCGGCTCCT GTGCCCGCTG 60
TGCGGGAAGC CCATGCGCGA GCCCGTGCAG GTTTCTACCT GCGGCCACCG CTTCTGCGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR002083--MATH/TRAF_dom
IPR012227--TNF_rcpt--assoc_TRAF
IPR008974--TRAF-like
IPR027138--TRAF4
IPR018957--Znf_C3HC4_RING-type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
IPR001293--Znf_TRAF

PROSITE

PS50144--MATH
PS00518--ZF_RING_1
PS50089--ZF_RING_2
PS50145--ZF_TRAF

Pfam

PF00097--zf-C3HC4
PF02176--zf-TRAF

SMART

SM00061--MATH
SM00184--RING

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0007250--P:activation of NF-kappaB-inducing kinase activity
GO:0046330--P:positive regulation of JNK cascade
GO:0090073--P:positive regulation of protein homodimerization activity
GO:0042981--P:regulation of apoptotic process
GO:0007585--P:respiratory gaseous exchange
GO:0030323--P:respiratory tube development

KEGG

lav:100660891

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000797	Aegilops tauschii	42.25	3.00e-08	53.10
IUUC-Aml-001287	Ailuropoda melanoleuca	97.23	0.00e+00	905.00
IUUC-Ame-011530	Astyanax mexicanus	77.45	0.00e+00	773.00
IUUC-Bta-013582	Bos taurus	98.72	0.00e+00	924.00
IUUC-Cja-019883	Callithrix jacchus	93.75	3.00e-51	193.00
IUUC-Cfa-020133	Canis familiaris	92.34	0.00e+00	854.00
IUUC-Cpo-022021	Cavia porcellus	98.72	0.00e+00	926.00
IUUC-Csa-023199	Chlorocebus sabaeus	98.72	0.00e+00	926.00
IUUC-Cgl-026455	Colletotrichum gloeosporioides	23.15	6.00e-16	78.60
IUUC-Dre-028193	Danio rerio	76.60	0.00e+00	768.00
IUUC-Dno-028917	Dasypus novemcinctus	99.15	0.00e+00	928.00
IUUC-Ete-032433	Echinops telfairi	97.87	0.00e+00	915.00
IUUC-Fca-036155	Felis catus	98.51	0.00e+00	924.00
IUUC-Gmo-038860	Gadus morhua	77.45	0.00e+00	770.00
IUUC-Ggr-040084	Gaeumannomyces graminis	27.16	2.00e-10	60.50
IUUC-Gga-041052	Gallus gallus	81.49	0.00e+00	832.00
IUUC-Gac-041489	Gasterosteus aculeatus	77.45	0.00e+00	769.00
IUUC-Ggo-044996	Gorilla gorilla	98.09	0.00e+00	921.00
IUUC-Hsa-046252	Homo sapiens	98.30	0.00e+00	924.00
IUUC-Hvu-047127	Hordeum vulgare	38.03	2.00e-07	49.70
IUUC-Itr-048232	Ictidomys tridecemlineatus	98.94	0.00e+00	926.00
IUUC-Kpa-049340	Komagataella pastoris	26.46	1.00e-15	77.80
IUUC-Loc-052312	Lepisosteus oculatus	77.28	0.00e+00	769.00
IUUC-Lma-053014	Leptosphaeria maculans	22.64	8.00e-14	72.00
IUUC-Mcc-055684	Macaca mulatta	98.72	0.00e+00	926.00
IUUC-Mpo-057517	Magnaporthe poae	24.91	5.00e-11	62.80
IUUC-Mmr-061198	Microcebus murinus	98.94	0.00e+00	926.00
IUUC-Mdo-062585	Monodelphis domestica	87.45	0.00e+00	832.00
IUUC-Mmu-064303	Mus musculus	97.66	0.00e+00	920.00
IUUC-Mac-064529	Musa acuminata	30.40	1.00e-10	60.50
IUUC-Mpu-066854	Mustela putorius furo	98.09	0.00e+00	922.00
IUUC-Nle-070098	Nomascus leucogenys	97.02	0.00e+00	910.00
IUUC-Ont-071518	Oreochromis niloticus	77.61	0.00e+00	771.00
IUUC-Ocu-073841	Oryctolagus cuniculus	98.72	0.00e+00	925.00
IUUC-Ola-086674	Oryzias latipes	77.40	0.00e+00	768.00
IUUC-Oga-088510	Otolemur garnettii	98.72	0.00e+00	925.00
IUUC-Oar-089225	Ovis aries	94.89	0.00e+00	880.00
IUUC-Pan-092725	Papio anubis	98.72	0.00e+00	926.00
IUUC-Pfo-096341	Poecilia formosa	77.40	0.00e+00	771.00
IUUC-Pop-099898	Populus trichocarpa	27.07	5.00e-08	52.00
IUUC-Pva-103131	Pteropus vampyrus	99.62	5.00e-144	504.00
IUUC-Pte-104279	Pyrenophora teres	21.98	5.00e-13	69.70
IUUC-Pyt-104429	Pyrenophora triticirepentis	21.98	7.00e-13	68.60
IUUC-Rno-105996	Rattus norvegicus	97.87	0.00e+00	920.00
IUUC-Sly-111800	Solanum lycopersicum	30.00	8.00e-06	46.60
IUUC-Tru-117602	Takifugu rubripes	78.09	0.00e+00	778.00
IUUC-Tur-126067	Triticum urartu	42.25	2.00e-08	53.50

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence