iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Pma-094643

UUCD1 version

UUC-PeM-00427

Ensembl Protein ID

ENSPMAP00000010739.1

UniProt Accession

S4RZU8; S4RZU8_PETMA

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPMAG00000009767.1	ENSPMAT00000010785.1	ENSPMAP00000010739.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	1.30e-103	346.1	540	866

Active Site

Position(s)	Description	Evidence
835	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 2    ksdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldl 90
           ++dlkk+l+vef+gE+g+d gGv++ef++l+++el+npd+g+f+++e+ +  ++ np+s     e++  F+++G++lg+a++++ +ld+
   Q: 540  PADLKKQLYVEFEGEQGVDEGGVSKEFFQLVVEELFNPDIGMFTFDESTRLFWF-NPSSL----ENEGQFTLIGIVLGLAIYNNCILDI 623
           689****************************************99998777766.88887....6899********************* PP
   S: 91   plsksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfs.vseeilgetkeeeLkpgGenipVtneNkeeYvklvv 178
           +++ ++y++l+gk+ +++dl++ +p ly+slk ++++ e ++e+  +  tf     + +g+  +++Lk++Ge+ipVtn+Nk+e+v+l++
   Q: 624  HFPMVVYRKLMGKRGTFHDLADSHPALYQSLKDLLAY-EGSVEDD-IMATFRiSYFDMFGTPITQDLKENGEDIPVTNDNKKEFVDLYA 710
           *************************************.5677775.77777724556699999999*********************** PP
   S: 179  eyrlkegikeqveafreGfneviple.llslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerkafLq 266
           ey+l++++++q++afr+Gf+ v +++ l +lF++ee+ell+cG++ +d+++l++ t+y+gg++++s++i+ Fw+++++f +++++ fLq
   Q: 711  EYILNQSVEKQFKAFRRGFHMVTSESpLKALFRPEEVELLVCGSRVLDFHALEDATEYDGGFNKSSRVIRDFWDTVHDFCEDKKRLFLQ 799
           ***********************99946678********************************************************** PP
   S: 267  FvTgssrlPlgGfaelkprlfvirkdasd.drlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFel 335
           F+Tg++r+P+gG+ +lk   ++i k++ d drlP+++TCfn+L LPeYss e+lke+Ll Ai+++kgF++
   Q: 800  FTTGTDRAPVGGLGKLK---MIIAKNGPDsDRLPTAHTCFNVLLLPEYSSREKLKERLLKAITHAKGFGM 866
           *****************...8888877777**************************************97 PP

Organism

Petromyzon marinus

Protein Sequence
(Fasta)

RRKRAAVKQM IERYYHQLTE GCGNTSCSNE FCASSPAFKP LDNNSAAIRA VELCRNKAKL 60
CDPHPSKRGA SLCHIDYYPE ADLASQFSTV LLYKSDNIHF PDVRFLTEEK LEEIMQTCTS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGCAGGAAGC GTGCAGCTGT GAAGCAGATG ATAGAGCGGT ATTATCACCA GCTGACGGAA 60
GGCTGTGGCA ACACCAGCTG CTCCAACGAA TTCTGTGCCT CCAGTCCAGC GTTCAAGCCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR032353--AZUL
IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF16558--AZUL
PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002214	Ailuropoda melanoleuca	71.87	0.00e+00	1229.00
IUUC-Atr-003144	Amborella trichopoda	45.00	3.00e-96	343.00
IUUC-Apl-003742	Anas platyrhynchos	72.13	0.00e+00	1236.00
IUUC-Aca-004873	Anolis carolinensis	71.33	0.00e+00	1230.00
IUUC-Acl-008288	Aspergillus clavatus	32.56	9.00e-79	287.00
IUUC-Afl-008402	Aspergillus flavus	33.83	2.00e-72	265.00
IUUC-Afu-008762	Aspergillus fumigatus	33.84	2.00e-81	295.00
IUUC-Ani-009176	Aspergillus nidulans	38.95	8.00e-79	287.00
IUUC-Ang-009791	Aspergillus niger	33.67	1.00e-77	283.00
IUUC-Aor-009921	Aspergillus oryzae	33.67	6.00e-72	264.00
IUUC-Ate-010295	Aspergillus terreus	32.07	5.00e-81	294.00
IUUC-Ame-011166	Astyanax mexicanus	72.11	0.00e+00	1227.00
IUUC-Bgr-011981	Blumeria graminis	37.53	3.00e-80	292.00
IUUC-Bta-013286	Bos taurus	72.02	0.00e+00	1213.00
IUUC-Bci-013697	Botrytis cinerea	36.23	4.00e-68	252.00
IUUC-Cja-019707	Callithrix jacchus	71.89	0.00e+00	1234.00
IUUC-Cfa-020154	Canis familiaris	71.56	0.00e+00	1227.00
IUUC-Cpo-021292	Cavia porcellus	71.41	0.00e+00	1221.00
IUUC-Cre-022790	Chlamydomonas reinhardtii	49.69	3.00e-81	293.00
IUUC-Csa-023378	Chlorocebus sabaeus	71.66	0.00e+00	1235.00
IUUC-Cho-025059	Choloepus hoffmanni	68.43	0.00e+00	1156.00
IUUC-Cin-025643	Ciona intestinalis	48.45	0.00e+00	633.00
IUUC-Csv-026282	Ciona savignyi	49.62	4.00e-171	593.00
IUUC-Cgl-026526	Colletotrichum gloeosporioides	37.75	2.00e-79	289.00
IUUC-Cme-027151	Cyanidioschyzon merolae	44.70	2.00e-100	358.00
IUUC-Dre-027901	Danio rerio	71.66	0.00e+00	1222.00
IUUC-Dno-029320	Dasypus novemcinctus	70.99	0.00e+00	1222.00
IUUC-Dor-030756	Dipodomys ordii	83.04	4.00e-168	583.00
IUUC-Dse-031239	Dothistroma septosporum	35.36	4.00e-72	265.00
IUUC-Dme-032035	Drosophila melanogaster	49.42	4.00e-163	567.00
IUUC-Ete-032902	Echinops telfairi	36.67	9.00e-86	310.00
IUUC-Eca-033843	Equus caballus	71.26	0.00e+00	1203.00
IUUC-Eeu-035109	Erinaceus europaeus	70.62	0.00e+00	1193.00
IUUC-Fca-036344	Felis catus	71.79	0.00e+00	1226.00
IUUC-Fal-036747	Ficedula albicollis	72.13	0.00e+00	1236.00
IUUC-Fox-037941	Fusarium oxysporum	40.18	2.00e-87	315.00
IUUC-Fso-038388	Fusarium solani	40.40	4.00e-87	315.00
IUUC-Gmo-038840	Gadus morhua	58.64	0.00e+00	1004.00
IUUC-Gga-040399	Gallus gallus	72.13	0.00e+00	1237.00
IUUC-Gac-041933	Gasterosteus aculeatus	70.79	0.00e+00	1169.00
IUUC-Ggo-044804	Gorilla gorilla	71.77	0.00e+00	1234.00
IUUC-Hsa-045727	Homo sapiens	71.77	0.00e+00	1234.00
IUUC-Itr-048289	Ictidomys tridecemlineatus	68.85	0.00e+00	1163.00
IUUC-Lch-050197	Latimeria chalumnae	79.00	0.00e+00	1092.00
IUUC-Loc-052743	Lepisosteus oculatus	71.33	0.00e+00	1231.00
IUUC-Lma-053245	Leptosphaeria maculans	34.19	4.00e-56	212.00
IUUC-Laf-053615	Loxodonta africana	71.61	0.00e+00	1237.00
IUUC-Mcc-054934	Macaca mulatta	71.66	0.00e+00	1234.00
IUUC-Meu-056061	Macropus eugenii	69.63	0.00e+00	1149.00
IUUC-Mor-057045	Magnaporthe oryzae	37.18	1.00e-79	290.00
IUUC-Mla-059187	Melampsora laricipopulina	37.56	6.00e-66	243.00
IUUC-Mga-059271	Meleagris gallopavo	72.10	0.00e+00	1233.00
IUUC-Mmr-061288	Microcebus murinus	72.00	0.00e+00	1239.00
IUUC-Mdo-062975	Monodelphis domestica	71.67	0.00e+00	1234.00
IUUC-Mmu-063674	Mus musculus	77.16	0.00e+00	1065.00
IUUC-Mpu-066568	Mustela putorius furo	71.67	0.00e+00	1231.00
IUUC-Mlu-067522	Myotis lucifugus	74.89	0.00e+00	995.00
IUUC-Nfi-068439	Neosartorya fischeri	38.14	6.00e-80	291.00
IUUC-Ncr-068903	Neurospora crassa	37.66	3.00e-76	278.00
IUUC-Nle-069505	Nomascus leucogenys	71.77	0.00e+00	1234.00
IUUC-Opr-070570	Ochotona princeps	66.09	0.00e+00	1105.00
IUUC-Ont-071527	Oreochromis niloticus	71.02	0.00e+00	1241.00
IUUC-Oan-073446	Ornithorhynchus anatinus	65.66	0.00e+00	742.00
IUUC-Ocu-074922	Oryctolagus cuniculus	71.67	0.00e+00	1231.00
IUUC-Ola-086996	Oryzias latipes	70.28	0.00e+00	1222.00
IUUC-Oga-088261	Otolemur garnettii	71.94	0.00e+00	1236.00
IUUC-Oar-090024	Ovis aries	72.02	0.00e+00	1213.00
IUUC-Ptr-090455	Pan troglodytes	71.77	0.00e+00	1234.00
IUUC-Pan-092509	Papio anubis	70.26	0.00e+00	1095.00
IUUC-Psi-092974	Pelodiscus sinensis	72.02	0.00e+00	1217.00
IUUC-Pno-094886	Phaeosphaeria nodorum	35.86	1.00e-58	220.00
IUUC-Ppa-095354	Physcomitrella patens	44.26	1.00e-107	383.00
IUUC-Pfo-096905	Poecilia formosa	77.02	0.00e+00	1076.00
IUUC-Pab-097840	Pongo abelii	77.00	0.00e+00	1053.00
IUUC-Pca-100869	Procavia capensis	71.12	0.00e+00	1220.00
IUUC-Pva-103040	Pteropus vampyrus	81.55	2.00e-165	574.00
IUUC-Pgr-103315	Puccinia graminis	39.32	2.00e-77	282.00
IUUC-Ptt-103736	Puccinia triticina	39.57	1.00e-77	283.00
IUUC-Rno-105453	Rattus norvegicus	77.61	0.00e+00	1070.00
IUUC-Sce-106306	Saccharomyces cerevisiae	36.71	5.00e-64	238.00
IUUC-Sha-107651	Sarcophilus harrisii	71.56	0.00e+00	1233.00
IUUC-Ssl-108657	Sclerotinia sclerotiorum	36.66	8.00e-75	274.00
IUUC-Smo-108858	Selaginella moellendorffii	39.70	1.00e-115	408.00
IUUC-Sar-113293	Sorex araneus	71.84	0.00e+00	1234.00
IUUC-Ssc-115979	Sus scrofa	71.49	0.00e+00	1228.00
IUUC-Tgu-116901	Taeniopygia guttata	72.13	0.00e+00	1236.00
IUUC-Tru-118368	Takifugu rubripes	71.00	0.00e+00	1236.00
IUUC-Tsy-119516	Tarsius syrichta	68.94	0.00e+00	1144.00
IUUC-Tni-120143	Tetraodon nigroviridis	71.00	0.00e+00	1238.00
IUUC-Tre-122108	Trichoderma reesei	39.52	1.00e-75	276.00
IUUC-Tvi-122644	Trichoderma virens	38.14	5.00e-77	281.00
IUUC-Tme-127004	Tuber melanosporum	33.72	3.00e-82	299.00
IUUC-Tbe-127484	Tupaia belangeri	64.52	0.00e+00	805.00
IUUC-Ttr-129078	Tursiops truncatus	71.61	0.00e+00	1221.00
IUUC-Vda-129969	Verticillium dahliae	38.85	2.00e-83	303.00
IUUC-Vpa-130312	Vicugna pacos	64.22	0.00e+00	1020.00
IUUC-Xtr-132881	Xenopus tropicalis	77.19	0.00e+00	1081.00
IUUC-Xma-133122	Xiphophorus maculatus	77.17	0.00e+00	1074.00
IUUC-Yli-134470	Yarrowia lipolytica	36.27	1.00e-61	230.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence